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Akademický článek

Sex-dependent temporal changes in astrocyte-vessel interactions following diffuse traumatic brain injury in rats

Autor: Zackary Sabetta, Gokul Krishna, Tala Curry-Koski, Mackenzie Lopez, P. David Adelson, Theresa Currier Thomas

Publikováno v: Frontiers in Physiology, Vol 15 (2024)

Traumatic brain injury (TBI) is associated with diffuse axonal injury (DAI), a primary pathology linked to progressive neurodegeneration and neuroinflammation, including chronic astrogliosis, which influences long-term post-TBI recovery and morbidity

Externí odkaz: https://doaj.org/article/8e47ba1387954ab9aed29ec5e6c2b72d

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Akademický článek

Neurotrauma Prevention Review: Improving Helmet Design and Implementation

Autor: Michael Goutnik, Joel Goeckeritz, Zackary Sabetta, Tala Curry, Matthew Willman, Jonathan Willman, Theresa Currier Thomas, Brandon Lucke-Wold

Publikováno v: Biomechanics, Vol 2, Iss 4, Pp 500-512 (2022)

Neurotrauma continues to contribute to significant mortality and disability. The need for better protective equipment is apparent. This review focuses on improved helmet design and the necessity for continued research. We start by highlighting curren

Externí odkaz: https://doaj.org/article/7c4f10dfcc39443e8205d029b5581684

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Sex-dependent Cerebrovascular Aging and Vulnerability to Traumatic Brain Injury in a Transgenic Mouse Model of a Fibrillin-1 Associated Connective Tissue Disorder

Autor: Tala Curry, Mary-Eunice Barrameda, Liam Curtin, Caitlin Hair, Gokul Krishna, Zackary Sabetta, Theresa Thomas, Mitra Esfandiarei

Publikováno v: Physiology. 38

Marfan syndrome (MFS) is a connective tissue disorder (CTD) associated with mutations in fibrillin-1 (Fbn1), leading to systemic increases in transforming growth factor-β (TGF-β) availability and signaling that induces an accelerated vascular aging

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::88d1c894e8f3ebc3f7375e939e99fa7b
https://doi.org/10.1152/physiol.2023.38.s1.5731438

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Transforming growth factor-beta elicits extracellular glutamate overflow in the lateral hippocampus in mice; a novel mechanism for TGF-beta to mediate neurological deficits

Autor: Liam Curtin, Caitlin Bromberg, Gokul Krishna, Zackary Sabetta, Tala Curry, Theresa Currier Thomas

Publikováno v: Physiology. 38

Transforming Growth Factor-β (TGF-β) is a multifunctional cytokine expressed in virtually every cell type of the human body. It has various roles throughout the body and is heavily reliant on cellular and environmental context, with major roles in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ae9639265554f6893a21916568490e9
https://doi.org/10.1152/physiol.2023.38.s1.5735184

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Aging with TBI vs. Aging: 6-month temporal profiles for neuropathology and astrocyte activation converge in behaviorally relevant thalamocortical circuitry of male and female rats

Autor: Zackary Sabetta, Gokul Krishna, Tala Curry, P. David Adelson, Theresa Currier Thomas

Publikováno v: bioRxiv

Traumatic brain injury (TBI) manifests late-onset and persisting clinical symptoms with implications for sex differences and increased risk for the development of age-related neurodegenerative diseases. Few studies have evaluated chronic temporal pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df2e9cb14d4dceeb97f01d309a64bcaf
https://europepmc.org/articles/PMC9934568/

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Measurement of Endothelium-dependent Vasorelaxation in the Mouse Thoracic Aorta using Tensometric Small Volume Chamber Myography

Autor: Mitra Esfandiarei, Tala Curry, Robert Folk, Brikena Gusek

Publikováno v: Journal of visualized experiments : JoVE. (186)

Small volume chamber tensometric myography is a commonly used technique to evaluate the vascular contractility of small and large blood vessels in laboratory animals and small arteries isolated from human tissue. The technique allows researchers to m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc99203e95a9bd5053cf6ec3ee6e7b8
https://pubmed.ncbi.nlm.nih.gov/36036616

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