Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Takuya Urushihata"'
Autor:
Takuya Urushihata, Mio Goto, Keiko Kabetani, Mai Kiyozuka, Shiho Maruyama, Shogo Tsuji, Hirobumi Tada, Akiko Satoh
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Sleep deprivation (SD) causes several adverse functional outcomes, and understanding the associated processes can improve quality of life. Although the effects of SD on neuronal activity in several brain regions have been identified, a comprehensive
Externí odkaz:
https://doaj.org/article/9b0e0baae00f493b859e0b98af416a7b
Autor:
Takehiro Kudo, Hiroyuki Takuwa, Manami Takahashi, Takuya Urushihata, Masafumi Shimojo, Kazuaki Sampei, Mitsugu Yamanaka, Yutaka Tomita, Naruhiko Sahara, Tetsuya Suhara, Makoto Higuchi
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106342- (2023)
Summary: In Alzheimer’s disease (AD), network hyperexcitability is frequently observed and associated with subsequent cognitive impairment. Dysfunction of inhibitory interneurons (INs) is thought to be one of the key biological mechanisms of hypere
Externí odkaz:
https://doaj.org/article/5f7c5b6f3d714688a91843c1e22d0942
Autor:
Takuya Urushihata, Hiroyuki Takuwa, Manami Takahashi, Jeff Kershaw, Sayaka Shibata, Nobuhiro Nitta, Yasuhiko Tachibana, Masato Yasui, Makoto Higuchi, Takayuki Obata
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2023)
IntroductionAs the movement of water in the brain is known to be involved in neural activity and various brain pathologies, the ability to assess water dynamics in the brain will be important for the understanding of brain function and the diagnosis
Externí odkaz:
https://doaj.org/article/85484b1c0b864adba6c3676ce780e62b
Autor:
Takuya Urushihata, Hiroyuki Takuwa, Manami Takahashi, Jeff Kershaw, Yasuhiko Tachibana, Nobuhiro Nitta, Sayaka Shibata, Masato Yasui, Makoto Higuchi, Takayuki Obata
Publikováno v:
European Radiology Experimental, Vol 5, Iss 1, Pp 1-11 (2021)
Abstract Background Aquaporin-4 is a membrane channel protein that is highly expressed in brain astrocytes and facilitates the transport of water molecules. It has been suggested that suppression of aquaporin-4 function may be an effective treatment
Externí odkaz:
https://doaj.org/article/c3b18bbf5d3648a0a1b769ba99fa3d7c
Autor:
Manami Takahashi, Takuya Urushihata, Hiroyuki Takuwa, Kazumi Sakata, Yuhei Takado, Eiji Shimizu, Tetsuya Suhara, Makoto Higuchi, Hiroshi Ito
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2018)
Green fluorescence imaging (e.g., flavoprotein autofluorescence imaging, FAI) can be used to measure neuronal activity and oxygen metabolism in living brains without expressing fluorescence proteins. It is useful for understanding the mechanism of va
Externí odkaz:
https://doaj.org/article/609f603f73984bfab7b8e50652c88d68
Autor:
Keisuke Nagashima, Jun Maeda, Ichio Aoki, Shoko Uchida, Hiroyuki Takuwa, Masafumi Shimojo, Maiko Ono, Kazuhisa Shibata, Sayaka Shibata, Nobuhiro Nitta, Takuya Urushihata, Yuhei Takado, Manami Takahashi, Yoshihiro Ochi, Yutaka Tomita, Jamie Near, Makoto Higuchi, Kazuaki Sampei, Naruhiko Sahara
Publikováno v:
J Cereb Blood Flow Metab
To assess if magnetic resonance spectroscopy (MRS)-measured Glutamate (Glu) and GABA reflect excitatory and inhibitory neural activities, respectively, we conducted MRS measurements along with two-photon mesoscopic imaging of calcium signals in excit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272ecf2ed0a2811f8ab1e4241d074223
https://doi.org/10.1177/0271678x211045449
https://doi.org/10.1177/0271678x211045449
Autor:
Yuhei, Takado, Hiroyuki, Takuwa, Sampei, Kazuaki, Takuya, Urushihata, Takahashi, Manami, Masafumi, Shimojo, Shoko, Uchida, Nobuhiro, Nitta, Sayaka, Shibata, Keisuke, Nagashima, Yoshihiro, Ochi, Maiko, Ono, Jun, Maeda, Yutaka, Tomita, Naruhiko, Sahara, Near, Jamie, Ichio, Aoki, Kazuhisa, Shibata, Makoto, Higuchi
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 42(1):197-212
To assess if magnetic resonance spectroscopy (MRS)-measured Glutamate (Glu) and GABA reflect excitatory and inhibitory neural activities, respectively, we conducted MRS measurements along with two-photon mesoscopic imaging of calcium signals in excit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::fab4de792e6e88a694c3ce752481ff02
https://repo.qst.go.jp/records/84651
https://repo.qst.go.jp/records/84651
Autor:
Takuya Urushihata, Hiroyuki Takuwa, Manami Takahashi, Je◻ Kershaw, Sayaka Shibata, Nobuhiro Nitta, Yasuhiko Tachibana, Masato Yasui, Makoto Higuchi, Obata Takayuki
As the movement of water in the brain is known to be involved in neural activity and various brain pathologies, the ability to assess water dynamics in the brain will be important for the understanding of brain function and the diagnosis and treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::998edced7474181f4e80b377b87c3f73
https://doi.org/10.1101/2022.10.02.510567
https://doi.org/10.1101/2022.10.02.510567
Autor:
Justin G. English, Toshiyuki Hirabayashi, Jing Liu, Koki Mimura, Masahiko Takada, Jin Nakahara, Tetsuya Suhara, Jian Jin, Naohisa Miyakawa, Bin Ji, Yukiko Hori, Maiko Ono, Manami Takahashi, Yan Xiong, Jeffrey F. DiBerto, Ken-ichi Inoue, Bryan L. Roth, Masafumi Shimojo, Chie Seki, Atsushi Fujimoto, Kei Oyama, Samuel T. Slocum, Yuji Nagai, Xi Ping Huang, Yutaka Tomita, Takafumi Minamimoto, Katsushi Kumata, Makoto Higuchi, Hiroyuki Takuwa, Ming-Rong Zhang, Takuya Urushihata
Publikováno v:
Nature Neuroscience. 23:1157-1167
The chemogenetic technology designer receptors exclusively activated by designer drugs (DREADDs) afford remotely reversible control of cellular signaling, neuronal activity and behavior. Although the combination of muscarinic-based DREADDs with cloza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f969bef8a60a645242632bbca53a4820
https://doi.org/10.1038/s41593-020-0661-3
https://doi.org/10.1038/s41593-020-0661-3
Autor:
Muneki Isokawa, Mai Nishimura, Sakiko Toyoda, Masafumi Shimojo, Hiroyuki Takuwa, Maiko Ono, Keiichiro Minatohara, Masako Tsukamoto-Yasui, Kenji Nagao, Manami Takahashi, Satoko Ueno, Hideaki Sato, Akira Mitsui, Takuya Urushihata, Naruhiko Sahara, Katsuya Suzuki, Sachise Karakawa, Akihiko Kitamura, Noriko Kawasaki, Yuhei Takado, Asumi Orihara, Makoto Higuchi, Mayuka Kanda, Jun Maeda, Ichio Aoki, Mika Kawasaki
Publikováno v:
Science Advances
Description
Intake of specific seven essential amino acids affects the pathology of the brain.
Protein malnutrition is epidemiologically suggested as a potential risk factor for senile dementia, although molecular mechanisms linking dietary
Intake of specific seven essential amino acids affects the pathology of the brain.
Protein malnutrition is epidemiologically suggested as a potential risk factor for senile dementia, although molecular mechanisms linking dietary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445f7124932f9d43d421c52d99c6e205
https://pubmed.ncbi.nlm.nih.gov/34678069
https://pubmed.ncbi.nlm.nih.gov/34678069