LOX-1 mediates inflammatory activation of microglial cells through the p38-MAPK/NF-κB pathways under hypoxic-ischemic conditions

Autor: Yoshinori Aoki, Hongmei Dai, Fumika Furuta, Tomohisa Akamatsu, Takuya Oshima, Naoto Takahashi, Yu-ichi Goto, Akira Oka, Masayuki Itoh

Publikováno v: Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-13 (2023)

Abstract Background Microglial cells play an important role in the immune system in the brain. Activated microglial cells are not only injurious but also neuroprotective. We confirmed marked lectin-like oxidized low-density lipoprotein receptor-1 (LO

Externí odkaz: https://doaj.org/article/c601080a670f43a59035a34ea080107a

Numerical Study on the Intrinsic Instability of High-Temperature Premixed Flames under the Conditions of Constant Density and Constant Pressure in the Unburned Gas

Autor: Satoshi KADOWAKI, Takuya OSHIMA, Hideaki KOBAYASHI

Publikováno v: Journal of Fluid Science and Technology, Vol 8, Iss 3, Pp 233-246 (2013)

We studied numerically the intrinsic instability of high-temperature premixed flames, where the burned-gas temperature was constant, under the conditions of constant density and constant pressure in the unburned gas. A sinusoidal disturbance with suf

Externí odkaz: https://doaj.org/article/96f6835d93104fe3953b1bb7d9b2ddf8

Prevention of microgliosis halts early memory loss in a mouse model of Alzheimer's disease

Autor: Mandy S.J. Kater, Christiaan F.M. Huffels, Takuya Oshima, Niek S. Renckens, Jinte Middeldorp, Erik W.G.M. Boddeke, August B. Smit, Bart J.L. Eggen, Elly M. Hol, Mark H.G. Verheijen

Publikováno v: Kater, M S J, Huffels, C F M, Oshima, T, Renckens, N S, Middeldorp, J, Boddeke, E W G M, Smit, A B, Eggen, B J L, Hol, E M & Verheijen, M H G 2023, ' Prevention of microgliosis halts early memory loss in a mouse model of Alzheimer's disease ', Brain, Behavior, and Immunity, vol. 107, pp. 225-241 . https://doi.org/10.1016/j.bbi.2022.10.009
Brain, Behavior, and Immunity, 107, 225-241. Academic Press Inc.
Brain, Behavior, and Immunity, 107, 225-241. ACADEMIC PRESS INC ELSEVIER SCIENCE

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline, the neuropathological formation of amyloid-beta (Aβ) plaques and neurofibrillary tangles. The best cellular correlates of the early cognitive deficits in AD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef7f012a683b584dc42584643bd653e
https://hdl.handle.net/1871.1/27713396-05ac-485a-8689-5dd0566972f6

Influence of vehicle source directivity in Japanese and European outdoor sound prediction models under a semi-finite thick barrier configuration

Autor: Fumiya Takeda, Takuya Oshima, Yumi Kurosaka

Publikováno v: INTER-NOISE and NOISE-CON Congress and Conference Proceedings. 263:5147-5153

The Japanese ASJ RTN-Model 2018, European Harmonoise and CNOSSOS-EU outdoor sound prediction models are respectively known to have symmetric, asymmetric and omnidirectional sound emission directivities along front-back direction of the source vehicle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b618dd07edf959aa6e8d88f33c70817d
https://doi.org/10.3397/in-2021-2980

Extensive study of receiver point interpolation methods for drawing estimated road traffic noise maps in Japanese city blocks

Autor: Yasuhiro Hiraguri, Kazunori Harada, Akiko Sugahara, Satoshi Atobe, Yudai Yamashiro, Yoshinori Saito, Takuya Oshima

Publikováno v: INTER-NOISE and NOISE-CON Congress and Conference Proceedings. 263:4329-4335

There are various issues need to be addressed when drawing estimated road traffic noise maps in Japan. One of them is there is a trade-off between computational load and estimation accuracy due to the number of sound receiver points on the building f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7299965f1f2696a33582d6b16938944c
https://doi.org/10.3397/in-2021-2663