Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Takuya Noguchi"'
Autor:
Shuhei Hamano, Takuya Noguchi, Yukino Asai, Ryo Ito, Ryuto Komatsu, Tetsu Sato, Aya Inoue, Tomoe Maruyama, Tada-aki Kudo, Yusuke Hirata, Sawako Shindo, Yasuo Uchida, Gi-Wook Hwang, Atsushi Matsuzawa
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Overactivation of poly (ADP-ribose) polymerase-1 (PARP-1) triggers a noncanonical form of programmed cell death (PCD) called parthanatos, yet the mechanisms of its induction are not fully understood. We have recently demonstrated that the ag
Externí odkaz:
https://doaj.org/article/b7f5edef378747cea8f183b47365b8da
Autor:
Yusuke Hirata, Naoki Kashiwabara, Yuki Nada, Aya Inoue, Emiko Sato, Takuya Noguchi, Atsushi Matsuzawa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract trans-Fatty acids (TFAs) are unsaturated fatty acids containing at least one carbon–carbon double bond in trans configuration, which are classified into two groups according to their food source: industrial TFAs (iTFAs) and ruminant TFAs (
Externí odkaz:
https://doaj.org/article/ca2bdae0ca8944b59ea43e486db866cc
Autor:
Takumi Yokosawa, Sayoko Miyagawa, Wakana Suzuki, Yuki Nada, Yusuke Hirata, Takuya Noguchi, Atsushi Matsuzawa
Publikováno v:
Cells, Vol 13, Iss 8, p 687 (2024)
Toll-like receptors (TLRs) induce innate immune responses through activation of intracellular signaling pathways, such as MAP kinase and NF-κB signaling pathways, and play an important role in host defense against bacterial or viral infections. Mean
Externí odkaz:
https://doaj.org/article/daadd732fe4540948f36ff0e765d687e
Autor:
Kanako Tominami, Tada-aki Kudo, Takuya Noguchi, Yohei Hayashi, You-Ran Luo, Takakuni Tanaka, Ayumu Matsushita, Satoshi Izumi, Hajime Sato, Keiko Gengyo-Ando, Atsushi Matsuzawa, Guang Hong, Junichi Nakai
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 772 (2024)
PC12 cells, which are derived from rat adrenal pheochromocytoma cells, are widely used for the study of neuronal differentiation. NGF induces neuronal differentiation in PC12 cells by activating intracellular pathways via the TrkA receptor, which res
Externí odkaz:
https://doaj.org/article/b80f29a8f6b54c52b558af5d7c7543ee
Autor:
Takashi Toyama, Takayuki Hoshi, Takuya Noguchi, Yoshiro Saito, Atsushi Matsuzawa, Akira Naganuma, Gi-Wook Hwang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract We recently found that tumor necrosis factor-α (TNF-α) may be involved in neuronal cell death induced by methylmercury in the mouse brain. Here, we examined the cells involved in the induction of TNF-α expression by methylmercury in the m
Externí odkaz:
https://doaj.org/article/aca787f298bc4591813bd5c3c424b4f7
Autor:
Yusuke Hirata, Miki Takahashi, Yuto Yamada, Ryosuke Matsui, Aya Inoue, Ryo Ashida, Takuya Noguchi, Atsushi Matsuzawa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract trans-Fatty acids (TFAs) are food-derived fatty acids associated with various diseases including cardiovascular diseases. However, the underlying etiology is poorly understood. Here, we show a pro-apoptotic mechanism of TFAs such as elaidic
Externí odkaz:
https://doaj.org/article/10e32ffef03445fa95dcd28b136361ce
Autor:
Takuya Noguchi, Yuto Sekiguchi, Yuki Kudoh, Rio Naganuma, Tomohiro Kagi, Akiko Nishidate, Kazuhiro Maeda, Chizuru Ishii, Takashi Toyama, Yusuke Hirata, Gi-Wook Hwang, Atsushi Matsuzawa
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-17 (2021)
Abstract Anticancer drug gefitinib causes inflammation-based side effects, such as interstitial pneumonitis. However, its mechanisms remain unknown. Here, we provide evidence that gefitinib elicits pro-inflammatory responses by promoting mature-inter
Externí odkaz:
https://doaj.org/article/8caaaf62bd0b45138093e5fa58c4ec7a
Autor:
You-Ran Luo, Tada-aki Kudo, Kanako Tominami, Satoshi Izumi, Takakuni Tanaka, Yohei Hayashi, Takuya Noguchi, Atsushi Matsuzawa, Junichi Nakai, Guang Hong, Hang Wang
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15602 (2022)
This study evaluated the mechanism of temperature-controlled repeated thermal stimulation (TRTS)-mediated neuronal differentiation. We assessed the effect of SP600125, a c-Jun N-terminal kinase (JNK) inhibitor, on neuronal differentiation of rat PC12
Externí odkaz:
https://doaj.org/article/e44097990eea4e08965ad6297b7851b3
Autor:
Tatsuya Shimada, Yohsuke Yabuki, Takuya Noguchi, Mei Tsuchida, Ryuto Komatsu, Shuhei Hamano, Mayuka Yamada, Yusuke Ezaki, Yusuke Hirata, Atsushi Matsuzawa
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 10064 (2022)
Liver kinase B1 (LKB1) is a serine/threonine protein kinase that acts as a key tumor suppressor protein by activating its downstream kinases, such as AMP-activated protein kinase (AMPK). However, the regulatory actions of LKB1 and AMPK on DNA damage
Externí odkaz:
https://doaj.org/article/a3f3212c68684a388efabc831a2ccaf2
Autor:
Takuya Noguchi, Makoto Kyougoku
Publikováno v:
Hong Kong Journal of Occupational Therapy, Vol 34 (2021)
Aims This study was to test the reliability and validity of the Assessment of Positive Occupational 15 (APO-15) for individuals experiencing mental illness. Methods A sample of 408 people experiencing mental illness living in communities or admitted
Externí odkaz:
https://doaj.org/article/1da6ca3cb0754e96903670c8031b3960