Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Takuya Imamura"'
Autor:
Mai Takehara, Mitsuki Kyakuno, Kazuko Okamoto, Ichiro Tazawa, Nobuaki Furuno, Megumi Furumitsu, Kazuyoshi Ukena, Takuya Imamura, Takashi Takeuchi, Toshinori Hayashi
Publikováno v:
Endocrine Journal, Vol 71, Iss 2, Pp 181-191 (2024)
Vertebrate animals often exhibit sexual dimorphism in body shape. In mammals, decreases in sex hormones caused by testicular castration can affect body shape and occasionally lead to pathologies such as obesity. Post-castration obesity can also be pr
Externí odkaz:
https://doaj.org/article/7df556db8bac492dbe31f92ecb4426f9
Autor:
Keitaro YAMANOUCHI, Shizuka KATO, Yukie TANAKA, Masanari IKEDA, Yukina OSHIMO, Takanori SHIGA, Kei HATAMOTO, James CHAMBERS, Takuya IMAMURA, Ryuji HIRAMATSU, Kazuyuki UCHIDA, Fuko MATSUDA, Takashi MATSUWAKI, Tetsuya KOHSAKA
Publikováno v:
The Journal of Reproduction and Development, Vol 70, Iss 2, Pp 55-64 (2024)
The mammalian X chromosome exhibits enrichment in genes associated with germ cell development. Previously, we generated a rat model of Becker muscular dystrophy (BMD) characterized by an in-frame mutation in the dystrophin gene, situated on the X chr
Externí odkaz:
https://doaj.org/article/ecc08a81b4cf491cb44a10573b2b3d4f
Autor:
Mayuri Tokunaga, Takuya Imamura
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Microcephaly is characterized as a small head circumference, and is often accompanied by developmental disorders. Several candidate risk genes for this disease have been described, and mutations in non-coding regions are occasionally found in patient
Externí odkaz:
https://doaj.org/article/48acc31dafc44f23bccc1d801677de4c
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Consecutive sexual maturation (CSM), an abnormal reproductive phenomenon of a marine snail, Reishia clavigera, has occurred since 2017 in the vicinity of the Fukushima Daiichi Nuclear Power Plant after the nuclear disaster there. We hypothesized that
Externí odkaz:
https://doaj.org/article/7680c058a12d423594d5a00ee1038a5e
Autor:
Tomonori KAMEDA, Hideyuki NAKASHIMA, Takumi TAKIZAWA, Fumihito MIURA, Takashi ITO, Kinichi NAKASHIMA, Takuya IMAMURA
Publikováno v:
The Journal of Reproduction and Development, Vol 67, Iss 6, Pp 369-379 (2021)
Post-mitotic neurons do exhibit DNA methylation changes, contrary to the longstanding belief that the epigenetic pattern in terminally differentiated cells is essentially unchanged. While the mechanism and physiological significance of DNA demethylat
Externí odkaz:
https://doaj.org/article/05bf0e296b3d45e495e3c006aa04c7f3
Autor:
Shiori MINABE, Sho NAKAMURA, Eri FUKUSHIMA, Marimo SATO, Kana IKEGAMI, Teppei GOTO, Makoto SANBO, Masumi HIRABAYASHI, Junko TOMIKAWA, Takuya IMAMURA, Naoko INOUE, Yoshihisa UENOYAMA, Hiroko TSUKAMURA, Kei-Ichiro MAEDA, Fuko MATSUDA
Publikováno v:
The Journal of Reproduction and Development, Vol 66, Iss 4, Pp 369-375 (2020)
Accumulating evidence suggests that kisspeptin-GPR54 signaling is indispensable for gonadotropin-releasing hormone (GnRH)/gonadotropin secretion and consequent reproductive functions in mammals. Conventional Kiss1 knockout (KO) mice and rats are repo
Externí odkaz:
https://doaj.org/article/0e9ff334730b491cb8b0553ce5c4f9ae
Autor:
Kana IKEGAMI, Teppei GOTO, Sho NAKAMURA, Youki WATANABE, Arisa SUGIMOTO, Sutisa MAJARUNE, Kei HORIHATA, Mayuko NAGAE, Junko TOMIKAWA, Takuya IMAMURA, Makoto SANBO, Masumi HIRABAYASHI, Naoko INOUE, Kei-ichiro MAEDA, Hiroko TSUKAMURA, Yoshihisa UENOYAMA
Publikováno v:
The Journal of Reproduction and Development, Vol 66, Iss 4, Pp 359-367 (2020)
The present study aimed to evaluate whether novel conditional kisspeptin neuron-specific Kiss1 knockout (KO) mice utilizing the Cre-loxP system could recapitulate the infertility of global Kiss1 KO models, thereby providing further evidence for the f
Externí odkaz:
https://doaj.org/article/c186e5926f0a4370bf0d6cf650553e0b
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 6, Pp n/a-n/a (2021)
Abstract The brain consists of three major cell types: neurons and two glial cell types (astrocytes and oligodendrocytes). Although they are generated from common multipotent neural stem/precursor cells (NS/PCs), embryonic NS/PCs cannot generate all
Externí odkaz:
https://doaj.org/article/df802f33d6454cdd93e209a95c654f5c
Autor:
Hideyuki Nakashima, Keita Tsujimura, Koichiro Irie, Takuya Imamura, Cleber A. Trujillo, Masataka Ishizu, Masahiro Uesaka, Miao Pan, Hirofumi Noguchi, Kanako Okada, Kei Aoyagi, Tomoko Andoh-Noda, Hideyuki Okano, Alysson R. Muotri, Kinichi Nakashima
Publikováno v:
Cell Reports, Vol 35, Iss 7, Pp 109124- (2021)
Summary: Rett syndrome (RTT) is a severe neurological disorder, with impaired brain development caused by mutations in MECP2; however, the underlying mechanism remains elusive. We know from previous work that MeCP2 facilitates the processing of a spe
Externí odkaz:
https://doaj.org/article/0fed81b11b5247d3a98746060e307b29
Autor:
Ryunosuke Kitajima, Risako Nakai, Takuya Imamura, Tomonori Kameda, Daiki Kozuka, Hirohisa Hirai, Haruka Ito, Hiroo Imai, Masanori Imamura
Publikováno v:
Stem Cell Research, Vol 44, Iss , Pp - (2020)
Evolutionary developmental biology of our closest living relative, the chimpanzee (Pan troglodytes), is essential for understanding the origin of human traits. However, it is difficult to access developmental events in the chimpanzee in vivo because
Externí odkaz:
https://doaj.org/article/0b04fb96a3be4f948fbcb8dc82fc0986