Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Takuya Iino"'
Autor:
Takuya Iino, Manabu Nagao, Hidekazu Tanaka, Sachiko Yoshikawa, Junko Asakura, Makoto Nishimori, Masakazu Shinohara, Amane Harada, Shunsuke Watanabe, Tatsuro Ishida, Ken-ichi Hirata, Ryuji Toh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The pathophysiology of variant transthyretin (TTR) amyloidosis (ATTRv) is associated with destabilizing mutations in the TTR tetramer. However, why TTR with a wild-type genetic sequence misfolds and aggregates in wild-type transthyretin amyl
Externí odkaz:
https://doaj.org/article/0649b95f344746439c3c1bbcebaf3940
Autor:
Katsuhiro Murakami, Amane Harada, Ryuji Toh, Takuya Kubo, Keiko Miwa, Jeeeun Kim, Maria Kiriyama, Takuya Iino, Youichi Nishikawa, Shin-Nosuke Uno, Kohei Akatsuchi, Manabu Nagao, Tatsuro Ishida, Ken-ichi Hirata
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract High-density lipoprotein (HDL) cholesterol efflux capacity (CEC), which is a conventional metric of HDL function, has been associated with coronary heart disease risk. However, the CEC assay requires cultured cells and takes several days to
Externí odkaz:
https://doaj.org/article/1de9aa4def1445c6b15847a2a21ee1b1
Autor:
Yutaro Seto, Manabu Nagao, Takuya Iino, Amane Harada, Katsuhiro Murakami, Keiko Miwa, Masakazu Shinohara, Makoto Nishimori, Sachiko Yoshikawa, Junko Asakura, Tomoo Fujioka, Tatsuro Ishida, Ken-ichi Hirata, Ryuji Toh
Publikováno v:
Journal of Applied Laboratory Medicine; Jul2024, Vol. 9 Issue 4, p728-740, 13p
Autor:
Hayato, Tada, Hirofumi, Okada, Atsushi, Nohara, Ryuji, Toh, Amane, Harada, Katsuhiro, Murakami, Takuya, Iino, Manabu, Nagao, Tatsuro, Ishida, Ken-Ichi, Hirata, Masayuki, Takamura, Masa-Aki, Kawashiri
Publikováno v:
Circulation Journal. 87:806-812
Recently, the function of high-density lipoprotein (HDL), rather than the HDL cholesterol (HDL-C) level, has been attracting more attention in risk prediction for coronary artery disease (CAD).Methods and Results: Patients with clinically diagnosed f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe718bb8f59598b8c4b81851930bc86
https://doi.org/10.1253/circj.cj-22-0560
https://doi.org/10.1253/circj.cj-22-0560
Autor:
Sachiko Yoshikawa, Manabu Nagao, Ryuji Toh, Masakazu Shinohara, Takuya Iino, Yasuhiro Irino, Makoto Nishimori, Hidekazu Tanaka, Seimi Satomi-Kobayashi, Tatsuro Ishida, Ken-Ichi Hirata
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 322:H749-H761
To our knowledge, this study is the first to demonstrate that increased GLS1 expression and subsequent activation of glutaminolysis are associated with exacerbation of cardiac hypertrophy and fibrosis. Inhibiting GLS1 antagonized the adverse cardiac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4900b319442eb3aa2afa2e1c1224b0
https://doi.org/10.1152/ajpheart.00692.2021
https://doi.org/10.1152/ajpheart.00692.2021
Autor:
Daichi Fujimoto, Hiromasa Otake, Hiroyuki Kawamori, Takayoshi Toba, Manabu Nagao, Shinsuke Nakano, Kosuke Tanimura, Yu Takahashi, Yusuke Fukuyama, Shunsuke Kakizaki, Koichi Nakamura, Amane Harada, Katsuhiro Murakami, Takuya Iino, Ryuji Toh, Ken-ichi Hirata
Publikováno v:
Atherosclerosis. 345:44-50
Background and aims High-density lipoprotein (HDL) functionality is an important determinant of coronary artery disease (CAD) development. We recently developed cholesterol-uptake capacity (CUC), a rapid cell-free assay system that directly evaluates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392dfe6674696400c0e6fed57d507695
https://hdl.handle.net/20.500.14094/0100481893
https://hdl.handle.net/20.500.14094/0100481893
Autor:
Eriko, Hisamatsu, Manabu, Nagao, Ryuji, Toh, Yasuhiro, Irino, Takuya, Iino, Tetsuya, Hara, Hidekazu, Tanaka, Seimi, Satomi-Kobayashi, Tatsuro, Ishida, Ken-Ichi, Hirata
Publikováno v:
Kobe J Med Sci
A large amount of evidence suggests that high-density lipoprotein (HDL) has anti-atherosclerotic properties. HDL-cholesterol (HDL-C) has also been widely used as a marker of cardiovascular disease. Recently, it was reported that plasma HDL-C levels a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f376d269be766bf7275500c5317047e6
https://pubmed.ncbi.nlm.nih.gov/32814756
https://pubmed.ncbi.nlm.nih.gov/32814756
Autor:
Takuya Iino, Shunsuke Watanabe, Kazuto Yamashita, Eiya Tamada, Takehiro Hasegawa, Yasuhiro Irino, Shigeki Iwanaga, Amane Harada, Kenta Noda, Kouzou Suto, Tomokazu Yoshida
Publikováno v:
Journal of Applied Laboratory Medicine; Jul2021, Vol. 6 Issue 4, p834-845, 12p
Autor:
Jun-ichi Seike, Minoru Kiyota, Hideo Nishitani, Hitoshi Yagisawa, Yui Iwamae, Takuya Iino, Katsuhisa Kawai
Publikováno v:
Biochemical and Biophysical Research Communications. 380:736-741
START-GAP2, also termed as DLC2, is a START domain-containing RhoGAP and a negative regulator of RhoA and Cdc42. Although it was reported as a tumor suppresser gene product, the molecular basis for function of START-GAP2 remains to be clarified. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549a58cb462568b6381a700e0f587202
https://doi.org/10.1016/j.bbrc.2009.01.095
https://doi.org/10.1016/j.bbrc.2009.01.095
Publikováno v:
Molecular and cellular biology. 29(24)
The upregulation of Src family kinases (SFKs) has been implicated in cancer progression, but the molecular mechanisms regulating their transforming potentials remain unclear. Here we show that the transforming ability of all SFK members is suppressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86eddc4ac15a364a8e3dfaab8e87d325
https://pubmed.ncbi.nlm.nih.gov/19822664
https://pubmed.ncbi.nlm.nih.gov/19822664