Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Takuya Fukunaga"'
Autor:
Madoka Kawamura, Yohei Kobashi, Hiroaki Tanaka, Ayako Bohno-Mikami, Makoto Hamada, Yuji Ito, Takashi Hirata, Hiroki Ohara, Naoki Kojima, Hiroko Koretsune, Emi Gunji, Takuya Fukunaga, Shoko Inatani, Yoshitaka Hasegawa, Akinori Suzuki, Teisuke Takahashi, Hiroyuki Kakinuma
Publikováno v:
Journal of Medicinal Chemistry. 65:14599-14613
20-Hydroxyeicosatetraenoic acid (20-HETE) is one of the major oxidized arachidonic acid (AA) metabolites produced by cytochrome P450 (CYP) 4A11 and CYP4F2 isozymes in the human liver and kidney. Numerous studies have suggested the involvement of 20-H
Autor:
Yudai, Imai, Daisuke, Wakasugi, Ryo, Suzuki, Sota, Kato, Mami, Sugisaki, Masashi, Mima, Hiroh, Miyagawa, Mayumi, Endo, Natsuko, Fujimoto, Takuya, Fukunaga, Sayaka, Kato, Shoichi, Kuroda, Teisuke, Takahashi, Hiroyuki, Kakinuma
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 79:129050
Heparanase-1 (HPSE1) is an endo-β-d-glucuronidase that cleaves heparan sulfate proteoglycans into short-chain heparan sulfates (HS). The inhibition of HPSE1 has therapeutic potential for proteinuric diseases such as nephrotic syndrome because increa
Autor:
Tsutomu Ando, Yoshihisa Toda, Takuya Fukunaga, Chu Yiwen, Takeshi Aoki, Osamu Nozawa, Li Jun-ying, Akira Kawashima, Yuichi Terui
Publikováno v:
Tetrahedron Letters. 49:3067-3070
In the course of our screening program for novel glycine transporter inhibitors, we obtained a novel cyclic tetrapeptide (WSS2220) from the culture broth of Nonomuraea sp. The structure of WSS2220 was elucidated based on physicochemical data. WSS2220
Autor:
Akitsugu Yamamoto, Mitsuo Tagaya, Kiyotaka Hatsuzawa, Takuya Fukunaga, Masami Nagahama, Katsuko Tani
Publikováno v:
Journal of Cell Science. 113:3299-3307
We examined the effects of short chain and long chain ceramides on the stability of the Golgi apparatus. Short chain ceramides, C(2)- and C(6)-ceramides, blocked brefeldin A-induced Golgi disassembly without affecting the rapid release of Golgi coat
New cyclic tetrapeptides from Nonomuraea sp. TA-0426 that inhibit glycine transporter type 1 (GlyT1)
Autor:
Tsutomu Ando, Yuichi Terui, Yoshihisa Toda, Takuya Fukunaga, Yi‐wen Chu, Jun-ying Li, Takeshi Aoki
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:6321-6323
In the course of our search for natural antipsychotic agents, we isolated five new cyclic tetrapeptides from the fermentation broth of Nonomuraea sp. TA-0426. These compounds turned out to be analogues of WSS2220, which had been produced by the same
Autor:
Yuichi Terui, Yi‐wen Chu, Jun-ying Li, Tsutomu Ando, Yoshihisa Toda, Takuya Fukunaga, Takeshi Aoki
Publikováno v:
ChemInform. 40
In the course of our search for natural antipsychotic agents, we isolated five new cyclic tetrapeptides from the fermentation broth of Nonomuraea sp. TA-0426. These compounds turned out to be analogues of WSS2220, which had been produced by the same
Autor:
Yuichi Terui, Osamu Nozawa, Akira Kawashima, Takuya Fukunaga, Takeshi Aoki, Jun-ying Li, Tsutomu Ando, Yoshihisa Toda, Yi‐wen Chu
Publikováno v:
ChemInform. 39
Autor:
Mitsuo Tagaya, Akitsugu Yamamoto, Katsuko Tani, Takuya Fukunaga, Akiko Furuno, Kiyotaka Hatsuzawa
Publikováno v:
FEBS letters. 435(2-3)
N-Ethylmaleimide-sensitive factor (NSF) is required for multiple pathways of vesicle-mediated protein transport. Microinjection of a monoclonal anti-NSF antibody almost completely blocked brefeldin A-promoted Golgi disassembly without affecting the r