Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Takuya, Kuroda"'
Autor:
Takeshi Watanabe, Satoshi Yasuda, Shinji Kusakawa, Takuya Kuroda, Hatsue Furukawa, Mayumi Futamura, Shigekazu Shimizu, Akihiko Morishita, Shinko Hata, Akiko Koeda, Kana Komatsu, Yoji Sato
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 315-323 (2024)
Introduction: MEASURE2 (Multisite Evaluation Study on Analytical Methods for Non-clinical Safety Assessment of HUman-derived REgenerative Medical Products 2) is a Japanese experimental public–private partnership initiative that aims to standardize
Externí odkaz:
https://doaj.org/article/912fe7017d9e4325ae16d6184b69c4af
Autor:
Takuya Kuroda, Satoshi Yasuda, Satoko Matsuyama, Takumi Miura, Rumi Sawada, Akifumi Matsuyama, Yumiko Yamamoto, Masaki Suimye Morioka, Hideya Kawaji, Takeya Kasukawa, Masayoshi Itoh, Hidenori Akutsu, Jun Kawai, Yoji Sato
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Despite the development of various in vitro differentiation protocols for the efficient derivation of specific cell types, human induced pluripotent stem cell (hiPSC) lines have varing ability to differentiate into specific lineages. Therefo
Externí odkaz:
https://doaj.org/article/c183765f9ed7404eb3feb29ff62eda86
Autor:
Yoshitaka Shirasago, Hidesuke Fukazawa, Shotaro Nagase, Yoshimi Shimizu, Tomoharu Mizukami, Takaji Wakita, Tetsuro Suzuki, Hideki Tani, Masuo Kondoh, Takuya Kuroda, Satoshi Yasuda, Yoji Sato, Kentaro Hanada, Masayoshi Fukasawa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Entry of the hepatitis C virus (HCV) into host cells is a multistep process mediated by several host factors, including a tight junction protein claudin-1 (CLDN1). We repeatedly passaged HCV-JFH1-tau, an HCV substrain with higher infectivity
Externí odkaz:
https://doaj.org/article/6ab2437809074c90b54dbaa6bfc1c9e2
Autor:
Sayaka Oda, Kazuhiro Nishiyama, Yuka Furumoto, Yohei Yamaguchi, Akiyuki Nishimura, Xiaokang Tang, Yuri Kato, Takuro Numaga-Tomita, Toshiyuki Kaneko, Supachoke Mangmool, Takuya Kuroda, Reishin Okubo, Makoto Sanbo, Masumi Hirabayashi, Yoji Sato, Yasuaki Nakagawa, Koichiro Kuwahara, Ryu Nagata, Gentaro Iribe, Yasuo Mori, Motohiro Nishida
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Baroreflex control of cardiac contractility is essential to maintain cardiocirculatory homeostasis. Here, Oda et al show that α1 adrenoceptor-stimulated Zn2+ entry through TRPC6 channels boosts β adrenoceptor-dependent myocardial positive inotropy.
Externí odkaz:
https://doaj.org/article/e32d11cf533d41b3a910892e7315812a
Autor:
Takamasa Hirai, Ken Kono, Rumi Sawada, Takuya Kuroda, Satoshi Yasuda, Satoko Matsuyama, Akifumi Matsuyama, Naoya Koizumi, Naoki Utoguchi, Hiroyuki Mizuguchi, Yoji Sato
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Highly sensitive detection of residual undifferentiated pluripotent stem cells is essential for the quality and safety of cell-processed therapeutic products derived from human induced pluripotent stem cells (hiPSCs). We previously reported
Externí odkaz:
https://doaj.org/article/2735b6808bb54562a53b506bb3e6702e
Autor:
Takuya Kuroda, Satoshi Yasuda, Shiori Tachi, Satoko Matsuyama, Shinji Kusakawa, Keiko Tano, Takumi Miura, Akifumi Matsuyama, Yoji Sato
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Human induced pluripotent stem cells (hiPSCs) generate all cell types in the body, but different lines can differ in their potential. Here, the authors determine that higher endogenous levels of SALL3 in hiPSCs lead to ectoderm differentiation bias a
Externí odkaz:
https://doaj.org/article/46ec5862781d440890248a463ec73ca6
Autor:
Takuya Kuroda, Satoshi Yasuda, Hiroyuki Nakashima, Nozomi Takada, Satoko Matsuyama, Shinji Kusakawa, Akihiro Umezawa, Akifumi Matsuyama, Shin Kawamata, Yoji Sato
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Human pluripotent stem cells (hPSCs) are leading candidate raw materials for cell-based therapeutic products (CTPs). In the development of hPSC-derived CTPs, it is imperative to ensure that they do not form tumors after transplantation for s
Externí odkaz:
https://doaj.org/article/0840e66561c64d6fbe8d79444de7b309
Autor:
Satoshi Yasuda, Shinji Kusakawa, Takuya Kuroda, Takumi Miura, Keiko Tano, Nozomi Takada, Satoko Matsuyama, Akifumi Matsuyama, Michiyo Nasu, Akihiro Umezawa, Takao Hayakawa, Hideki Tsutsumi, Yoji Sato
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205022 (2018)
Human induced pluripotent stem cells (hiPSCs) represent promising raw materials of human cell-based therapeutic products (hCTPs). As undifferentiated hiPSCs exhibit intrinsic tumorigenicity properties that enable them to form teratomas, hCTPs contain
Externí odkaz:
https://doaj.org/article/e05fc1f3ac01447fbc2ef9c5fa9e15af
Autor:
Shinji Kusakawa, Kazuhiko Machida, Satoshi Yasuda, Nozomi Takada, Takuya Kuroda, Rumi Sawada, Hanayuki Okura, Hideki Tsutsumi, Shin Kawamata, Yoji Sato
Publikováno v:
Regenerative Therapy, Vol 1, Iss C, Pp 30-37 (2015)
The contamination of human cell-processed therapeutic products (hCTPs) with tumorigenic cells is one of the major concerns in the manufacturing and quality control of hCTPs. However, no quantitative method for detecting the tumorigenic cellular impur
Externí odkaz:
https://doaj.org/article/c476e3b89b7a4be5b39447e6839d167d
Autor:
Ken Kono, Hiroyuki Mizuguchi, Naoki Utoguchi, Akifumi Matsuyama, Satoko Matsuyama, Yoji Sato, Naoya Koizumi, Takamasa Hirai, Rumi Sawada, Satoshi Yasuda, Takuya Kuroda
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Highly sensitive detection of residual undifferentiated pluripotent stem cells is essential for the quality and safety of cell-processed therapeutic products derived from human induced pluripotent stem cells (hiPSCs). We previously reported the gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119e1234bdebad21db81306db02e624c
https://doaj.org/article/2735b6808bb54562a53b506bb3e6702e
https://doaj.org/article/2735b6808bb54562a53b506bb3e6702e