Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Takuto Kumano"'
Autor:
Takahiro Mori, Takuto Kumano, Haibing He, Satomi Watanabe, Miki Senda, Toshio Moriya, Naruhiko Adachi, Sanae Hori, Yuzu Terashita, Masato Kawasaki, Yoshiteru Hashimoto, Takayoshi Awakawa, Toshiya Senda, Ikuro Abe, Michihiko Kobayashi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
In C-glycosides the sugar moiety is linked through a carbon-carbon bond to the non-sugar moiety, which can be cleaved by intestinal microbes. Here, the authors use bioinformatics analysis to identify C-glycoside deglycosidase enzymes in intestinal an
Externí odkaz:
https://doaj.org/article/be2834e7f7604e8f81be75ba24bda5b8
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Little is known about the degradation pathway of cyclic imines that are frequently found in bioactive secondary metabolites. Here, the authors found and characterised a copper amine oxidase, HarA that catalyses a ring-opening reaction of cyclic imine
Externí odkaz:
https://doaj.org/article/765881ec59a145a2b90cd6c617ec662b
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178974 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0175846.].
Externí odkaz:
https://doaj.org/article/de27afbd1c464efead0dfabbb5dc71a1
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175846 (2017)
In general, hemoproteins are capable of catalyzing redox reactions. Aldoxime dehydratase (OxdA), which is a unique heme-containing enzyme, catalyzes the dehydration of aldoximes to the corresponding nitriles. Its reaction is a rare example of heme di
Externí odkaz:
https://doaj.org/article/ba4d7fbeb2984b5fbb2005b8516cd710
Autor:
Pu Jian1, Takuto Kumano1,2 kumano.takuto.fu@u.tsukuba.ac.jp, Mio Kimura1, Makoto Kurisaki1, Yoshiteru Hashimoto1,2, Michihiko Kobayashi1,2,3 kobayashi.m.fe@u.tsukuba.ac.jp
Publikováno v:
Applied & Environmental Microbiology. Nov2023, Vol. 89 Issue 11, p1-12. 12p.
Autor:
Masato Kawasaki, Haibing He, Yuzu Terashita, Michihiko Kobayashi, Takayoshi Awakawa, Yoshiteru Hashimoto, Naruhiko Adachi, Takahiro Mori, Toshio Moriya, Toshiya Senda, Takuto Kumano, Miki Senda, Sanae Hori, Satomi Watanabe, Ikuro Abe
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
C-Glycosides, in which a sugar moiety is linked via a carbon-carbon (C-C) bond to a non-sugar moiety (aglycone), are found in our food and medicine. The C-C bond is cleaved by intestinal microbes and the resulting aglycones exert various bioactivitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6efdd353691dbd38c09795d70b37f293
https://doaj.org/article/be2834e7f7604e8f81be75ba24bda5b8
https://doaj.org/article/be2834e7f7604e8f81be75ba24bda5b8
Publikováno v:
The Journal of General and Applied Microbiology. 67:24-32
Pseudomonas chlororaphis B23 yields nitrile hydratase (NHase) used for the production of 5-cyanovaleramide at the industrial level. Although the nhpC gene (known as P47K) located just downstream of the NHase structural genes (nhpAB) has been importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f15804829461976a3934f853955a254
https://doi.org/10.2323/jgam.2020.03.003
https://doi.org/10.2323/jgam.2020.03.003
Autor:
Satomi Watanabe, Toshiya Senda, Sanae Hori, Miki Senda, Hong Yang Yu, Yuzu Terashita, Takuto Kumano, Yoshiteru Hashimoto, Michihiko Kobayashi
Publikováno v:
Proceedings of the National Academy of Sciences. 118
Significance Microbial degradation of C -glycosides is only reported from human intestinal bacteria. This study isolated a C -glycoside–catabolizing bacteria, Microbacterium sp. 5-2b, from soil and identified a C -glycoside–metabolizing enzyme. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d001e701c40ee9141037b24aaa76868
https://doi.org/10.1073/pnas.2106580118
https://doi.org/10.1073/pnas.2106580118
Autor:
Takuto, Kumano, Sanae, Hori, Satomi, Watanabe, Yuzu, Terashita, Hong Yang, Yu, Yoshiteru, Hashimoto, Toshiya, Senda, Miki, Senda, Michihiko, Kobayashi
Publikováno v:
Proc Natl Acad Sci U S A
C-glycosides have a unique structure, in which an anomeric carbon of a sugar is directly bonded to the carbon of an aglycone skeleton. One of the natural C-glycosides, carminic acid, is utilized by the food, cosmetic, and pharmaceutical industries, f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2d7efc0edb0d937b75a546e9df625ae
https://pubmed.ncbi.nlm.nih.gov/34583991
https://pubmed.ncbi.nlm.nih.gov/34583991
Autor:
Tomoko Abe, Yoshiteru Hashimoto, Sayaka Sugimoto, Michihiko Kobayashi, Takuto Kumano, Kenta Kobayashi
Publikováno v:
The Journal of Antibiotics. 70:435-442
The adenylation domain of nonribosomal peptide synthetase (NRPS) is responsible for the selective substrate recognition and its activation (as an acyl-O-AMP intermediate) during ATP consumption. DhbE, a stand-alone adenylation domain, acts on an arom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e53fc4d0be3d321ca5601ad28df55c23
https://doi.org/10.1038/ja.2016.117
https://doi.org/10.1038/ja.2016.117