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Akademický článek

Biphasic Tracheal Relaxation Induced by Higenamine and Nantenine From Nandina domestica THUNBERG

Autor: Takuro Ueki, Tatsuhiro Akaishi, Hidenobu Okumura, Tsuneo Morioka, Kazuho Abe

Publikováno v: Journal of Pharmacological Sciences, Vol 115, Iss 2, Pp 254-257 (2011)

We compared the effects of the extract from fruits of Nandina domestica THUNBERG (NDE) and its constituents, higenamine and nantenine, on contractile responses in isolated guineapig trachea. NDE (1 mg/ml) caused biphasic relaxation of the trachea pre

Externí odkaz: https://doaj.org/article/a392e5d036a34399a5b71c277d2fce78

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Predicting the results of a 24-hr human patch test for surfactants: utility of margin-setting in a reconstructed human epidermis model

Autor: Shinichi Ogata, Hiroshi Itagaki, Takuro Ueki, Mariko Sugiyama

Publikováno v: The Journal of toxicological sciences. 44(6)

To predict the results of a 24-hr closed human patch test, we previously recommended the use of in vitro test with a reconstructed human epidermis (RhE) model adopted in OECD TG 439, and proposed the margin method, which includes evaluation of twice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67cee86b47113fc6eac1775efd84cf9
https://pubmed.ncbi.nlm.nih.gov/31167989

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Acute oral toxicity test of chemical compounds in silkworms

Autor: Yasuhiko Matsumoto, Satoshi Nishida, Takuro Ueki, Takuya Sugita, Kimihito Usui, Kazuhisa Sekimizu, Hidenobu Okumura

Publikováno v: Drug Discoveries & Therapeutics. 10:57-61

This study performed an acute oral toxicity test of 59 compounds in silkworms. These compounds are listed in OECD guidelines as standard substances for a cytotoxicity test, and median lethal dose (LD(50)) werecalculated for each compound. Acute oral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af3dfac9ee334831a7d032b07b31d17
https://doi.org/10.5582/ddt.2016.01025

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Extract from Nandina domestica Inhibits Lipopolysaccharide-Induced Cyclooxygenase-2 Expression in Human Pulmonary Epithelial A549 Cells

Autor: Takuro Ueki, Kazuho Abe, Hidenobu Okumura, Tatsuhiro Akaishi

Publikováno v: Biological and Pharmaceutical Bulletin. 35:1041-1047

Extract from fruits of Nandina domestica THUNBERG (NDE) has been used to improve cough and breathing difficulty in Japan for many years. To explore whether NDE may alleviate respiratory inflammation, we investigated its effect on expression of cycloo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72e3aba943d20764b07cf26a912f9c54
https://doi.org/10.1248/bpb.b110709

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Biphasic Tracheal Relaxation Induced by Higenamine and Nantenine From Nandina domestica THUNBERG

Autor: Tsuneo Morioka, Kazuho Abe, Takuro Ueki, Tatsuhiro Akaishi, Hidenobu Okumura

Publikováno v: Journal of Pharmacological Sciences, Vol 115, Iss 2, Pp 254-257 (2011)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b65862ea98dffb37dc3abbc9bbf3a4
https://doi.org/10.1254/jphs.10251sc

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β2-Adrenoceptor-Mediated Tracheal Relaxation Induced by Higenamine fromNandina domesticaThunberg

Autor: Kazuho Abe, Tatsuhiro Akaishi, Hiroko Kikuchi, Hidenobu Okumura, Takuro Ueki, Yoichi Yasuda, Muneo Tsukiyama

Publikováno v: Planta Medica. 75:1393-1399

The fruit of Nandina domestica Thunberg (ND, Berberidaceae) has been used to improve cough and breathing difficulties in Japan for many years, but very little is known about the constituent of ND responsible for this effect. We have recently reported

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc788aaa1f321c02081355fafae94da
https://doi.org/10.1055/s-0029-1185743

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Multiplicative mononuclear small hepatocytes in adult rat liver: Their isolation as a homogeneous population and localization to periportal zone

Autor: Katsutoshi Yoshizato, Chihiro Yamasaki, Akiko Aratani, Kinji Asahina, Miho Shiokawa, Chise Tateno, Takuro Ueki

Publikováno v: Biochemical and Biophysical Research Communications. 342:1160-1167

Adult rat liver contains a minor population of hepatocytes called small hepatocytes (SHs) that are smaller in size and show a higher replicative potential than conventional parenchymal hepatocytes (PHs). However, SHs have been hitherto characterized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886e61d64d993a2c2cd9fa8835726917
https://doi.org/10.1016/j.bbrc.2006.02.076

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The extract from Nandina domestica THUNBERG inhibits histamine- and serotonin-induced contraction in isolated guinea pig trachea

Autor: Muneo Tsukiyama, Takuro Ueki, Kazuho Abe, Tatsuhiro Akaishi, Hidenobu Okumura

Publikováno v: Biologicalpharmaceutical bulletin. 30(11)

Although the fruit of Nandina domestica THUNBERG (ND) has been used to treat respiratory disorders such as coughing and breathing difficulty in Japan for many years, very little is known about mechanisms underlying its action. In the present study, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8891caa8e054887f3f560ac5057bc1b
https://pubmed.ncbi.nlm.nih.gov/17978476

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