Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Takuro Tojima"'
Autor:
Hirokazu Yagi, Seigo Tateo, Taiki Saito, Yusaku Ohta, Emiko Nishi, Saemi Obitsu, Tatsuya Suzuki, Supaphorn Seetaha, Charles Hellec, Akihiko Nakano, Takuro Tojima, Koichi Kato
Publikováno v:
Cell Structure and Function, Vol 49, Iss 2, Pp 47-55 (2024)
The Golgi apparatus, a crucial organelle involved in protein processing, including glycosylation, exhibits complex sub-structures, i.e., cis-, medial, and trans-cisternae. This study investigated the distribution of glycosyltransferases within the Go
Externí odkaz:
https://doaj.org/article/773bbe37ee2c4458984c2ab5ac35d2e1
Autor:
Akihiro Harada, Masataka Kunii, Kazuo Kurokawa, Takuya Sumi, Satoshi Kanda, Yu Zhang, Satomi Nadanaka, Koichiro M. Hirosawa, Kazuaki Tokunaga, Takuro Tojima, Manabu Taniguchi, Kenta Moriwaki, Shin-ichiro Yoshimura, Miki Yamamoto-Hino, Satoshi Goto, Toyomasa Katagiri, Satoshi Kume, Mitsuko Hayashi-Nishino, Miyako Nakano, Eiji Miyoshi, Kenichi G. N. Suzuki, Hiroshi Kitagawa, Akihiko Nakano
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Knowledge on the distribution and dynamics of glycosylation enzymes in the Golgi is essential for better understanding this modification. Here, using a combination of CRISPR/Cas9 knockin technology and super-resolution microscopy, we show th
Externí odkaz:
https://doaj.org/article/fd8fce91b1f74602a6b152cacc39ff8a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Optical microscopy is essential for direct observation of dynamic phenomena in living cells. According to the classic optical theories, the images obtained through light microscopes are blurred for about half the wavelength of light, and therefore sm
Externí odkaz:
https://doaj.org/article/70fba4960b9f41238eef33ef4ed55d75
Publikováno v:
eLife, Vol 13 (2024)
Cargo traffic through the Golgi apparatus is mediated by cisternal maturation, but it remains largely unclear how the cis-cisternae, the earliest Golgi sub-compartment, is generated and how the Golgi matures into the trans-Golgi network (TGN). Here,
Externí odkaz:
https://doaj.org/article/04911ad0d3ce43839b254203620eb876
Autor:
Yuuki Obata, Kazuo Kurokawa, Takuro Tojima, Miyuki Natsume, Isamu Shiina, Tsuyoshi Takahashi, Ryo Abe, Akihiko Nakano, Toshirou Nishida
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113035- (2023)
Summary: Most gastrointestinal stromal tumors (GISTs) develop due to gain-of-function mutations in the tyrosine kinase gene, KIT. We recently showed that mutant KIT mislocalizes to the Golgi area and initiates uncontrolled signaling. However, the mol
Externí odkaz:
https://doaj.org/article/42d0f84a4a38424993fb2a24722927da
Autor:
Junko Y Toshima, Ayana Tsukahara, Makoto Nagano, Takuro Tojima, Daria E Siekhaus, Akihiko Nakano, Jiro Toshima
Publikováno v:
eLife, Vol 12 (2023)
Although budding yeast has been extensively used as a model organism for studying organelle functions and intracellular vesicle trafficking, whether it possesses an independent endocytic early/sorting compartment that sorts endocytic cargos to the en
Externí odkaz:
https://doaj.org/article/6989e2957cc74299ad5841c5d4c7ec1d
Autor:
Yuuki Obata, Kazuo Kurokawa, Takuro Tojima, Miyuki Natsume, Isamu Shiina, Tsuyoshi Takahashi, Ryo Abe, Akihiko Nakano, Toshirou Nishida
SUMMARYMost gastrointestinal stromal tumors (GISTs) develop due to gain-of-function mutations in the tyrosine kinase,KIT. We recently showed that mutant KIT mislocalizes to the Golgi area and initiates uncontrolled signaling. However, the molecular m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4740be7d1acd61743b02c808ad4b8dfc
https://doi.org/10.1101/2022.12.19.520889
https://doi.org/10.1101/2022.12.19.520889
Publikováno v:
Methods in Molecular Biology ISBN: 9781071626382
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3a5189a872562a1402c2df184ea3ae8
https://doi.org/10.1007/978-1-0716-2639-9_10
https://doi.org/10.1007/978-1-0716-2639-9_10
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2557
Super-resolution confocal live imaging microscopy (SCLIM) we developed provides high-speed, high-resolution, three- and four-dimensional, and multicolor simultaneous imaging. Using this technology, we are now able to observe the fine details of vario
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76e523d83945fa60d39b9bdc5d3a2da1
https://pubmed.ncbi.nlm.nih.gov/36512214
https://pubmed.ncbi.nlm.nih.gov/36512214
Autor:
Junko Y. Toshima, Ayana Tsukahara, Makoto Nagano, Takuro Tojima, Daria E. Siekhaus, Akihiko Nakano, Jiro Toshima
Although budding yeast has been extensively used as a model organism for studying organelle functions and intracellular vesicle trafficking, whether it possesses an independent endocytic early/sorting compartment that sorts endocytic cargos to the en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c862a9a3882e3a571d33fd641ebeeeb
https://doi.org/10.1101/2022.11.21.517324
https://doi.org/10.1101/2022.11.21.517324