Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Takunori Nagashima"'
Autor:
Muhammad Irfanur Rashid, Takuji Ito, Fuyuki Miya, Daisuke Shimojo, Kanae Arimoto, Kazunari Onodera, Rina Okada, Takunori Nagashima, Kazuki Yamamoto, Zohora Khatun, Rayhanul Islam Shimul, Jun-ichi Niwa, Masahisa Katsuno, Gen Sobue, Hideyuki Okano, Hidetoshi Sakurai, Kazunori Shimizu, Manabu Doyu, Yohei Okada
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-22 (2023)
Abstract Pathophysiological analysis and drug discovery targeting human diseases require disease models that suitably recapitulate patient pathology. Disease-specific human induced pluripotent stem cells (hiPSCs) differentiated into affected cell typ
Externí odkaz:
https://doaj.org/article/b86903a1ae624984930cf68c5276e193
Autor:
Kazunori Shimizu, Haruo Kassai, Yuhei Kamei, Kazuki Yamamoto, Takunori Nagashima, Tadayoshi Maekawa, Hirokazu Akiyama, Hiroyuki Honda
Publikováno v:
Cells, Vol 11, Iss 23, p 3760 (2022)
In vitro neuromuscular junction (NMJ) models are powerful tools for studying neuromuscular disorders. Although linearly patterned culture surfaces have been reported to be useful for the formation of in vitro NMJ models using mouse motor neuron (MNs)
Externí odkaz:
https://doaj.org/article/595b911200954f4f8d677397e47a57d0
Autor:
Kazuki Yamamoto, Saki Ohsumi, Takunori Nagashima, Hirokazu Akiyama, Hiroyuki Honda, Kazunori Shimizu
Publikováno v:
Biotechnology and Bioengineering. 119:2196-2205
Skeletal muscle atrophy is characterized by decreases in protein content, myofiber diameter, and contractile force generation. As muscle atrophy worsens the quality of life, the development of anti-atrophic substances is desirable. In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed629e437f9cd8d91a10e72e3c1e55f
https://doi.org/10.1002/bit.28125
https://doi.org/10.1002/bit.28125
Autor:
Takuji Ito, Yohei Okada, Yu Imaizumi, Kazunori Shimizu, Nao Yamaoka, Kazuki Yamamoto, Taiki Furutani, Takunori Nagashima, Hiroyuki Honda
Publikováno v:
Lab on a Chip. 21(10):1897-1907
Engineered three-dimensional models of neuromuscular tissues are promising for use in mimicking their disorder states in vitro. Although several models have been developed, it is still challenging to mimic the physically separated structures of motor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f794ee991ce816e508beb35bcf735217
https://nagoya.repo.nii.ac.jp/records/2001615
https://nagoya.repo.nii.ac.jp/records/2001615
Autor:
Muhammad Irfanur Rashid, Takuji Ito, Daisuke Shimojo, Kanae Arimoto, Kazunari Onodera, Rina Okada, Takunori Nagashima, Kazuki Yamamoto, Zohora Khatun, Hideyuki Okano, Hidetoshi Sakurai, Kazunori Shimizu, Manabu Doyu, Yohei Okada
Pathophysiological analysis and drug discovery targeting human diseases require disease models that suitably recapitulate patients’ pathology. Disease-specific human induced pluripotent stem cells (hiPSCs) can potentially recapitulate disease patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8335c9a47adf1332c5632f79a2787120
https://doi.org/10.1101/2021.11.22.468571
https://doi.org/10.1101/2021.11.22.468571
Autor:
Kazuki Yamamoto, Takuji Ito, Yohei Okada, Taiki Furutani, Nao Yamaoka, Takunori Nagashima, Yu Imaizumi, Hiroyuki Honda, Kazunori Shimizu
Engineered three-dimensional models of neuromuscular tissues are promising for use in mimicking their disorder states in vitro. Although several models have been developed, it is still challenging to mimic the physically separated structures of motor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f571c39e94b4ffc831348a7e7014fe7e
https://doi.org/10.1101/2021.01.07.424253
https://doi.org/10.1101/2021.01.07.424253
Autor:
Hiroyuki Honda, Saki Ohsumi, Yohei Okada, Takumi Hisada, Stacy Hadiwidjaja, Ryuji Kato, Kazunori Shimizu, Takunori Nagashima, Akari Murata
Publikováno v:
Advanced Biosystems. 4:2000121
In the development process for drugs used to treat skeletal muscle, cell-based contractile force assays have been considered as a useful in vitro test. Immortalized human myogenic cells are promising as cell sources for reproducible and well-characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579196eefa85869b9fa32c95ed0880e7
https://doi.org/10.1002/adbi.202000121
https://doi.org/10.1002/adbi.202000121
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Human pluripotent stem cells, including human induced pluripotent stem cells (hiPSCs), serve as highly valuable sources for both cell-based therapies and basic research, owing to their abilities to self-renew and differentiate into any cell type of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938c7806a23e15104314e831a8c189a3
https://pubmed.ncbi.nlm.nih.gov/30127448
https://pubmed.ncbi.nlm.nih.gov/30127448