Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Takumichi Sugihara"'
Autor:
Ryouji Mizumachi, Yuuya Ono, Tomoyuki Hisa, Yoshitaka Furuya, Novriana Dewi, Hiroyuki Takahashi, Jun Nakajima, Tadao Nakashima, Masashi Nagata, Minoru Ono, Yasumasa Nonaka, Toshimitsu Terao, Yasuyuki Morishita, Takashi Fujino, Masashi Yanagawa, Koji Seguchi, Mitsuteru Fujihara, Masazumi Eriguchi, Kazuhiko Arimori, Kazuhiro Kakimi, Takeshi Nagasaki, Takumichi Sugihara, Hironobu Yanagie, Shushi Higashi, Yuuji Murata, Ichiro Ikushima, Takashi Imagawa
Publikováno v:
In Vivo
Background/aim A mixture of anticancer agents and iodized poppy seed oil (IPSO) has been widely used for intra-arterial chemotherapy of hepatocellular carcinoma. However, the anticancer agents can easily separate from IPSO, so the therapeutic potenti
Autor:
Masayuki Nashimoto, Atsuko Shinohara, Minoru Suzuki, Yoshitaka Furuya, Minoru Ono, Ryouji Mizumachi, Novriana Dewi, Koji Ono, Shin-ichiro Masunaga, Yuuji Murata, Hiroyuki Takahashi, Hiroki Tanaka, Takumichi Sugihara, Haruo Yamauchi, Hironobu Yanagie, Yoshinori Sakurai, Hiroyuki Nakamura, Yasumasa Nonaka, Masashi Yanagawa, Yasuyuki Morishita, Jun Nakajima
Publikováno v:
In Vivo
Background/Aim: Tumor cell destruction by boron neutron capture therapy (BNCT) is attributed to the nuclear reaction between (10)B and thermal neutrons. The accumulation of (10)B atoms in tumor cells without affecting adjacent healthy cells is crucia
Autor:
HIRONOBU YANAGIE, MASASHI YANAGAWA, YASUYUKI MORISHITA, ATSUKO SHINOHARA, NOVRIANA DEWI, YASUMASA NONAKA, YOSHITAKA FURUYA, RYOUJI MIZUMACHI, YUUJI MURATA, HIROYUKI NAKAMURA, MINORU SUZUKI, YOSHINORI SAKURAI, HIROKI TANAKA, SHINICHIRO MASUNAGA, KOJI ONO, TAKUMICHI SUGIHARA, MASAYUKI NASHIMOTO, HARUO YAMAUCHI, MINORU ONO, JUN NAKAJIMA
Publikováno v:
In Vivo; Nov/Dec2021, Vol. 35 Issue 6, p3125-3135, 11p
Publikováno v:
Natural product communications. 11(7)
Piceatannol (3,3′,4,5′-tetrahydroxy- trans-stilbene, 2), an oxygenated analog of resveratrol (1), was synthesized. It is one of the naturally occurring polyphenolic stilbenoids contained in red wine, and possesses many kinds of beneficial effects
Autor:
Takumichi Sugihara
Publikováno v:
YAKUGAKU ZASSHI. 135:89-92
Education in university is commonly based on active learning by the students themselves. Lectures, exercises, and training are major learning strategies in a university. Self-study is one of the methods of active learning and is considered to be a ma
Autor:
Takumichi Sugihara, Takafumi Nagatomo, Mohiuddin Ahmed Bhuiyan, Habib Abul Muntasir, Murad Hossain, Mamunur Rashid, Masaji Ishiguro
Publikováno v:
Biological & Pharmaceutical Bulletin. 35:1553-1559
We previously reported that sarpogrelate, a selective 5-HT2A antagonist, showed a potent inverse agonist activity to constitutively active mutant (C322K) of human 5-HT2A receptor (5-HT2AR). However, it remains to be unknown about the actual mechanism
Autor:
Takumichi Sugihara, Hiroshi Imagawa, Mugio Nishizawa, Hiroko Takao, Akihito Wakabayashi, Kazuya Takahashi
Publikováno v:
Tetrahedron Letters. 45:1079-1082
Course of cyclization of dienols, polyenes, and dienyne mediated by mercuric salts were controlled by stability of cationic intermediates and source of mercuric salts. Reaction of (E)-5,9-dimethyl-4,8-decadiene-1-ol with mercuric acetate gave the int
Publikováno v:
Tetrahedron Letters. 44:3867-3870
The first calculations of a C-ring model cation of sterol biosynthesis in the presence of selected counteranions have been performed. [TiCl4OH]− ion significantly stabilizes the perpendicular cation conformer that leads to carboncarbon bond migr
Publikováno v:
ChemInform. 45
Publikováno v:
Tetrahedron. 55:9469-9480
In the course of our study on neurotoxic C 17 -polyacetylenic alcohols of the toxic plant, Cicuta virosa , virols A ( 1 ), B ( 2 ), and C ( 3 ) were synthesized by stereoselective routes to confirm their stereochemistry and to obtain supply of these