Zobrazeno 1 - 10
of 301
pro vyhledávání: '"Takumi, Nishiuchi"'
Autor:
Hiroshi Kotani, Tomoyoshi Yamano, Justin C. Boucher, Shigeki Sato, Hiroyuki Sakaguchi, Koji Fukuda, Akihiro Nishiyama, Kaname Yamashita, Koushiro Ohtsubo, Shinji Takeuchi, Takumi Nishiuchi, Hiroko Oshima, Masanobu Oshima, Marco L. Davila, Seiji Yano
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-6 (2024)
Abstract Precision medicine has drastically changed cancer treatment strategies including KRAS-mutant cancers which have been undruggable for decades. While intrinsic or acquired treatment resistance remains unresolved in many cases, epigenome-target
Externí odkaz:
https://doaj.org/article/b9b2e0380ce9438081e69ef411f40371
Autor:
Hiroshi Kotani, Hiroko Oshima, Justin C. Boucher, Tomoyoshi Yamano, Hiroyuki Sakaguchi, Shigeki Sato, Koji Fukuda, Akihiro Nishiyama, Kaname Yamashita, Koushiro Ohtsubo, Shinji Takeuchi, Takumi Nishiuchi, Masanobu Oshima, Marco L. Davila, Seiji Yano
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-13 (2024)
Abstract Background KRAS mutations frequently occur in cancers, particularly pancreatic ductal adenocarcinoma, colorectal cancer, and non-small cell lung cancer. Although KRAS G12C inhibitors have recently been approved, effective precision therapies
Externí odkaz:
https://doaj.org/article/e76a3f8454924a68ab32ec86f27f0f26
Autor:
Yoko Uchida-Fukuhara, Shigeru Shimamura, Rikai Sawafuji, Takumi Nishiuchi, Minoru Yoneda, Hajime Ishida, Hirofumi Matsumura, Takumi Tsutaya
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Detailed investigation of extremely severe pathological conditions in ancient human skeletons is important as it could shed light on the breadth of potential interactions between humans and disease etiologies in the past. Here, we applied pa
Externí odkaz:
https://doaj.org/article/b82f840e52d54c6694f27bbb21d6d330
Autor:
Takahiro Ikari, Yukihiro Furusawa, Yoshiaki Tabuchi, Yusuke Maruyama, Atsuhiko Hattori, Yoichiro Kitani, Kenji Toyota, Arata Nagami, Jun Hirayama, Kazuki Watanabe, Atsushi Shigematsu, Muhammad Ahya Rafiuddin, Shouzo Ogiso, Keisuke Fukushi, Kohei Kuroda, Kaito Hatano, Toshio Sekiguchi, Ryotaro Kawashima, Ajai K. Srivastav, Takumi Nishiuchi, Akihiro Sakatoku, Masa-aki Yoshida, Hajime Matsubara, Nobuo Suzuki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Deep ocean water (DOW) exerts positive effects on the growth of marine organisms, suggesting the presence of unknown component(s) that facilitate their aquaculture. We observed that DOW suppressed plasma cortisol (i.e., a stress marker) conc
Externí odkaz:
https://doaj.org/article/38fb3aaf0f874f8d8bc913ee83bdbb63
An agroecological structure model of compost—soil—plant interactions for sustainable organic farming
Autor:
Hirokuni Miyamoto, Katsumi Shigeta, Wataru Suda, Yasunori Ichihashi, Naoto Nihei, Makiko Matsuura, Arisa Tsuboi, Naoki Tominaga, Masahiko Aono, Muneo Sato, Shunya Taguchi, Teruno Nakaguma, Naoko Tsuji, Chitose Ishii, Teruo Matsushita, Chie Shindo, Toshiaki Ito, Tamotsu Kato, Atsushi Kurotani, Hideaki Shima, Shigeharu Moriya, Satoshi Wada, Sankichi Horiuchi, Takashi Satoh, Kenichi Mori, Takumi Nishiuchi, Hisashi Miyamoto, Hiroaki Kodama, Masahira Hattori, Hiroshi Ohno, Jun Kikuchi, Masami Yokota Hirai
Publikováno v:
ISME Communications, Vol 3, Iss 1, Pp 1-12 (2023)
Abstract Compost is used worldwide as a soil conditioner for crops, but its functions have still been explored. Here, the omics profiles of carrots were investigated, as a root vegetable plant model, in a field amended with compost fermented with the
Externí odkaz:
https://doaj.org/article/fd3139ec8ab345c192e5871a8bea7717
Autor:
Marie Shinohara, Hiroshi Arakawa, Yuuichi Oda, Nobuaki Shiraki, Shinji Sugiura, Takumi Nishiuchi, Taku Satoh, Keita Iino, Sylvia Leo, Yusuke Kato, Karin Araya, Takumi Kawanishi, Tomoki Nakatsuji, Manami Mitsuta, Kosuke Inamura, Tomomi Goto, Kenta Shinha, Wataru Nihei, Kikuo Komori, Masaki Nishikawa, Shoen Kume, Yukio Kato, Toshiyuki Kanamori, Yasuyuki Sakai, Hiroshi Kimura
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Examining intestine–liver interactions is important for achieving the desired physiological drug absorption and metabolism response in in vitro drug tests. Multi-organ microphysiological systems (MPSs) constitute promising tools for evalua
Externí odkaz:
https://doaj.org/article/f3d6e51115fc431c979b3b6a3eb9921c
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 9014 (2023)
Millimeter-wave irradiation of wheat seeds enhances the growth of roots under flooding stress, but its mechanism is not clearly understood. To understand the role of millimeter-wave irradiation on root-growth enhancement, membrane proteomics was perf
Externí odkaz:
https://doaj.org/article/ea300c14d40142a6a2a842eb55432bcd
Autor:
Ayumi Kosaka, Marta Pastorczyk, Mariola Piślewska-Bednarek, Takumi Nishiuchi, Erika Ono, Haruka Suemoto, Atsushi Ishikawa, Henning Frerigmann, Masanori Kaido, Kazuyuki Mise, Paweł Bednarek, Yoshitaka Takano
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Nonhost resistance of Arabidopsis thaliana against the hemibiotrophic fungus Colletotrichum tropicale requires PEN2-dependent preinvasive resistance and CYP71A12 and CYP71A13-dependent postinvasive resistance, which both rely on tryptophan (
Externí odkaz:
https://doaj.org/article/7185c909e24c436b889b20840639238c
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12171 (2022)
The plant epidermis is the first line of plant defense against pathogen invasion, and likely contains important regulatory proteins related to the plant–pathogen interaction. This study aims to identify the candidates of these regulatory proteins e
Externí odkaz:
https://doaj.org/article/b108cbe8e0bd42db96f4061978d4240d
Autor:
Tamburrini, Ketty C., Sayo Kodama, Grisel, Sacha, Haon, Mireille, Takumi Nishiuchi, Bissaro, Bastien, Yasuyuki Kubo, Longhi, Sonia, Berrin, Jean-Guy
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 3/26/2024, Vol. 121 Issue 13, p1-12, 37p