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Akademický článek

Propensity-matched analysis of the efficacy of olanexidine gluconate versus chlorhexidine-alcohol as an antiseptic agent in thoracic esophagectomy

Autor: Takeo Fujita, Naoya Okada, Takuji Sato, Kazuma Sato, Hisashi Fujiwara, Takashi Kojima, Hiroyuki Daiko

Publikováno v: BMC Surgery, Vol 22, Iss 1, Pp 1-7 (2022)

Abstract Background In the present matched-cohort study, we investigated the efficacy of olanexidine gluconate in comparison with chlorhexidine-alcohol as an antiseptic agent in thoracic esophagectomy. Methods A total of 372 patients with esophageal

Externí odkaz: https://doaj.org/article/4d3ea0d529d742c5a9c8dc73665f6a22

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Akademický článek

Thoracoscopic esophagectomy with three-field lymphadenectomy for thoracic esophageal cancer in a patient with a double aortic arch: a report of a case

Autor: Hisashi Fujiwara, Takuji Sato, Naoya Okada, Takeo Fujita, Takashi Kojima, Hiroyuki Daiko

Publikováno v: Surgical Case Reports, Vol 5, Iss 1, Pp 1-7 (2019)

Abstract Background We encountered an esophageal cancer patient with a double aortic arch (DAA) who underwent radical thoracoscopic esophagectomy with three-field lymph node dissection. A DAA generally makes it difficult to perform upper mediastinal

Externí odkaz: https://doaj.org/article/426c61d5f6d64c6eb3182ab9830e21de

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Akademický článek

Non-occlusive mesenteric ischemia associated with enteral feeding after esophagectomy for esophageal cancer: report of two cases and review of the literature

Autor: Daisuke Kurita, Takeo Fujita, Yasumasa Horikiri, Takuji Sato, Hisashi Fujiwara, Hiroyuki Daiko

Publikováno v: Surgical Case Reports, Vol 5, Iss 1, Pp 1-9 (2019)

Abstract Background Non-occlusive mesenteric ischemia (NOMI) is a rare but life-threatening complication of early postoperative enteral feeding. We herein report two patients who developed NOMI during enteral feeding after esophagectomy. Case present

Externí odkaz: https://doaj.org/article/b5c9e17c1929473faccf1d2502279ae6

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Akademický článek

Internal hernia to the retrosternal space is a rare complication after minimally invasive esophagectomy: three case reports

Autor: Takuji Sato, Takeo Fujita, Hisashi Fujiwara, Hiroyuki Daiko

Publikováno v: Surgical Case Reports, Vol 5, Iss 1, Pp 1-4 (2019)

Abstract Background Minimally invasive esophagectomy is considered a beneficial approach to esophageal cancer, although a hiatal hernia occurs more frequently in this approach than in open esophagectomy with reconstruction via the mediastinal route.

Externí odkaz: https://doaj.org/article/bfbbe406bc034a14b6f155d7c338c9a4

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Supplementary Figure 8 from CBS9106-Induced CRM1 Degradation Is Mediated by Cullin Ring Ligase Activity and the Neddylation Pathway

Autor: Takumi Kawabe, Daniel D. VonHoff, Donald W. Kufe, Jonathan M. Friedman, Takuji Sato, Keiichi Sakakibara, Naoya Saito

Supplementary Figure 8: MLN4924 attenuates tumor growth inhibition by CBS9106 in human xenograft model. (A) SCID mice bearing HCT116 tumor xenografts are treated with vehicle (5% GA, p.o. + 10% HBC, s.c.), CBS9106 (250 mg/kg p.o. once per week), MLN4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9e48038b36b2f6bd252c9bd54185c9
https://doi.org/10.1158/1535-7163.22499652.v1

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Supplementary Figure 2 from CBS9106-Induced CRM1 Degradation Is Mediated by Cullin Ring Ligase Activity and the Neddylation Pathway

Autor: Takumi Kawabe, Daniel D. VonHoff, Donald W. Kufe, Jonathan M. Friedman, Takuji Sato, Keiichi Sakakibara, Naoya Saito

Supplementary Figure 2: MLN4924 (50 nM) increases subG1 and DNA content. HCT116 cells are treated with increasing concentrations of MLN4924 (0, 1, 10, or 50 nM) for 72 hours. The population is measured by flow cytometry after staining with propidium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0edb3814a383b57738d98b140c3658f0
https://doi.org/10.1158/1535-7163.22499670

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Supplementary Figure 1 from CBS9106-Induced CRM1 Degradation Is Mediated by Cullin Ring Ligase Activity and the Neddylation Pathway

Autor: Takumi Kawabe, Daniel D. VonHoff, Donald W. Kufe, Jonathan M. Friedman, Takuji Sato, Keiichi Sakakibara, Naoya Saito

Supplementary Figure 1: CBS9106 reduces CRM1 protein levels through neddylation -mediated degradation in MM.1S cells. (A) MM.1S cells are treated with CBS9106 (50 nM) and/or MLN4924 (100 nM) for indicated period (0-8 hours). (B) Cells are treated wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1dac22335be4ababc4fd71cffe4c02
https://doi.org/10.1158/1535-7163.22499673

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Supplementary Figure 6 from CBS9106-Induced CRM1 Degradation Is Mediated by Cullin Ring Ligase Activity and the Neddylation Pathway

Autor: Takumi Kawabe, Daniel D. VonHoff, Donald W. Kufe, Jonathan M. Friedman, Takuji Sato, Keiichi Sakakibara, Naoya Saito

Supplementary Figure 6: Inhibitors of autophagy do not interfere with the efficacy of low dose MLN4924. HCT116 cells are treated with CBS9106 (100 nM), MLN4924 (50 nM or 1 microM) or 3-MA (5 mM) alone or in combination for 24 hours. Protein levels of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a8e928ca7b4deccfebb2571b0bc4b5
https://doi.org/10.1158/1535-7163.22499658

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Supplementary Figure 3 from CBS9106-Induced CRM1 Degradation Is Mediated by Cullin Ring Ligase Activity and the Neddylation Pathway

Autor: Takumi Kawabe, Daniel D. VonHoff, Donald W. Kufe, Jonathan M. Friedman, Takuji Sato, Keiichi Sakakibara, Naoya Saito

Supplementary Figure 3: The cell growth inhibition and apoptosis by CBS9106 is suppressed by MLN4924 in MM.1S cells. (A) MM.1S cells are treated with the indicated concentration of CBS9106 and/or MLN4924 for 72 hours (n = 6). Cell viability is determ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7511f730693f2044f6d4f116f8115835
https://doi.org/10.1158/1535-7163.22499667

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