Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Takuji Nakatani"'
Publikováno v:
Angewandte Chemie International Edition. 43:6496-6500
Autor:
G.‐J. Shen, Chi-Huey Wong, Shirley Wacowich-Sgarbi, Takuji Nakatani, Masayuki Izumi, and Oliver Plettenburg
Publikováno v:
Journal of the American Chemical Society. 123:10909-10918
The alpha-2,3-sialyltransferase from Neisseria gonorrheae was overproduced in E. coli for exploitation of its substrate specificity and synthetic utility. Several potential acceptor substrates were synthesized in this study, including mono- and oligo
Autor:
Takuji Nakatani, Tadafumi Komurasaki, Mitsuaki Ohtani, Yoshinori Tamura, Kenji Kawada, Masanao Inagaki, Tatsuo Tsuri, Nobuhiro Haga, Masahiro Fuji, Shuji Yonezawa, Shozo Takechi, Akira Kugimiya, Teruhiko Taishi, Susumu Mitsumori
Publikováno v:
The Journal of Organic Chemistry. 63:5831-5837
We achieved a total synthesis of terprenin, a novel potent immunoglobulin E antibody suppressant which was obtained from the fermentation broth of Aspergillus candidus RF-5672 and has a highly oxygenated p-terphenyl skeleton with a prenyloxy side cha
Autor:
Yozo Hori, Kenji Kawada, Yoshitsugu Kokuryo, Akira Kugimiya, Yoshinori Tamura, Takuji Nakatani, Ryuji Suzuki, Kyozo Kawata, Mitsuaki Ohtani, Kenji Kuwabara, Mitsunobu Matsumoto
Publikováno v:
Journal of Medicinal Chemistry. 40:3280-3291
An ongoing search for new antifolate drugs useful against rheumatoid arthritis (RA) led us to prepare new methotrexate (MTX) derivatives containing enantiomerically pure L-erythro- or L-threo-gamma-fluoroglutamic acid. The derivatives in which the ph
Autor:
Takuji Nakatani, Mitsuaki Ohtani, Yoshinori Tamura, Kobee Kobayashi, Yoshitsugu Kokuryo, Kenji Kawada
Publikováno v:
Tetrahedron: Asymmetry. 7:3545-3551
Enantiomerically pure L- erythro - and L- threo -4-fluoroglutamic acids 1a and 1b were conveniently prepared. The key steps in this synthesis relied upon separation of diastereomers of N -chloroacetyl-4-fluoroglutamic acid 5-methyl ester 7 by recryst
Autor:
Kenji Kawada, Takuji Nakatani, Ryuji Suzuki, Ken Yasui, Mitsuaki Ohtani, Yoshinori Tamura, Kenzo Koizumi, Isao Horibe
Publikováno v:
The Journal of Antibiotics. 49:173-180
5beta-Methoxy (20), 14-methyl (24), 14,14-dibromo-15-nor (25), 8-O-acyl (26-45), 8-O-alkyl (46), 8-O-alkoxycarbonyl (47, 48), and 8-O-carbamoyl (49) derivatives of PA-48153C, a novel immunosuppressant isolated from fermentation products of Streptomyc
Publikováno v:
The Journal of Organic Chemistry. 60:7567-7574
Autor:
Jun Hiratake, Suzuki Tadao, Jun'ichi Oda, Akihiro Shinzaki, Hiroshi Nakajima, Takuji Nakatani, Ritsuko Umeshita, Takaaki Nishioka
Publikováno v:
Tetrahedron Letters. 34:4945-4948
A catalytic antibody capable of stereoselective ester hydrolysis was obtained. Chemical modification revealed that an Arg residue in the antibody combining site was responsible not only for the catalytic activity. but also for product inhibition by c
Publikováno v:
ChemInform. 27
Autor:
Yoshinori Tamura, K. Kobayashi, Takuji Nakatani, Kenji Kawada, Yoshitsugu Kokuryo, Mitsuaki Ohtani
Publikováno v:
ChemInform. 28