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Efficacy of Pseudo-Ceramide-Containing Steroid Lamellar Cream in Patients with Mild to Moderate Atopic Dermatitis: A Randomized, Double-Blind Study

Autor: Keita, Okoshi, Yoshinori, Kinugasa, Shotaro, Ito, Takuji, Kume, Tsuyoshi, Seki, Takahiro, Nishizaka, Joji, Okada, Hiromitsu, Kawada, Azumi, Nagasawa, Makoto, Iijima, Masatoshi, Abe, Osamu, Nemoto

Publikováno v: Dermatology and Therapy. 12:1823-1834

Atopic dermatitis (AD) is a chronic inflammatory skin disorder involving decreased barrier function of the stratum corneum. This decrease, caused by a reduction in ceramide, the primary component of intercellular lipids in the stratum corneum, leads

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0336f6da84855ce3e1bbf0ff661c8e1
https://doi.org/10.1007/s13555-022-00766-2

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Self-Assembled Structure of α-Isostearyl Glyceryl Ether Affects Skin Permeability—a Lamellar with 70-nm Spaces and L3 Phase Enhanced the Transdermal Delivery of a Hydrophilic Model Drug

Autor: Tomohiko Sano, Akie Okada, Kazunori Kawasaki, Takuji Kume, Minoru Fukui, Hiroaki Todo, Kenji Sugibayashi

Publikováno v: AAPS PharmSciTech. 23

Self-assembled surfactant structures, such as liquid crystals, have the potential to enhance transdermal drug delivery. In the present study, the pseudo-ternary system of GET (composed of α-Isostearyl glyceryl ether (GEIS) and polysorbate 60)/1,3 bu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685e83e83dcc560382b2b7c1334a97f7
https://doi.org/10.1208/s12249-022-02452-0

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A rheo-optical study on the linear viscoelasticity and molecular dynamics of block copolymer solutions forming hexagonal close-packed cylindrical domains

Autor: Takuji Kume, Eiko Tamura, Tadashi Inoue, Shigeru Okamoto

Publikováno v: Polymer Journal. 52:1085-1091

The linear viscoelastic properties of block copolymer solutions forming hexagonal close-packed cylindrical domains and their relaxation dynamics were investigated by using a rheo-optical method based on simultaneous measurements of stress and strain-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ad2571bb2cf3fe631d86953a814d6bb
https://doi.org/10.1038/s41428-020-0346-5

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Time Evolution of Structures under Shear-Induced Phase Separation and Crystallization in Semidilute Solution of Ultrahigh Molecular Weight Polyethylene

Autor: Takeji Hashimoto, Yasuo Ohta, Hiroki Murase, Takuji Kume

Publikováno v: Macromolecules. 38:8719-8728

We investigated shear-induced structures for a semidilute solution of ultrahigh molecular weight polyethylene (UHMWPE) with a paraffin wax as a solvent by means of shear small-angle light scattering, shear microscopy, birefringence, and rheology. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0ee18bed3b014ac7ad4ba2ef298de59
https://doi.org/10.1021/ma050092i

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Shear-Induced Structures in Semidilute Solution of Ultrahigh Molecular Weight Polyethylene at Temperature Close to Equilibrium Dissolution Temperature

Autor: Hiroki Murase, Yasuo Ohta, Takuji Kume, Takeji Hashimoto

Publikováno v: Macromolecules. 38:6656-6665

The shear-induced structure of a semidimute solution of ultrahigh molecular weight polyethylene (UHMWPE) with a paraffin wax as a solvent was investigated with shear small-angle light scattering (shear SALS) and shear microscopy. At a temperature of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b027cc98a52f31c879a2a2f765d3e1c
https://doi.org/10.1021/ma0476339

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