Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Taku Ozaki"'
Autor:
Lanlan Bai, Tetsuya Tani, Takeshi Kobayashi, Ryotaro Nouda, Yuta Kanai, Yusuke Sano, Kazutoshi Takami, Hiroshi Tomita, Eriko Sugano, Taku Ozaki, Tohru Kiyono, Tomokazu Fukuda
Publikováno v:
FEBS Open Bio, Vol 14, Iss 4, Pp 598-612 (2024)
The Egyptian Rousettus bat (Rousettus aegyptiacus) is a common fruit bat species that is distributed mainly in Africa and the Middle East. Bats serve as reservoir hosts for numerous pathogens. Human activities, such as hunting bats for food, managing
Externí odkaz:
https://doaj.org/article/ccc11fd0665e4e15bafae6e4a6104984
Publikováno v:
Biochemistry and Biophysics Reports, Vol 39, Iss , Pp 101768- (2024)
Calpains are calcium-dependent cysteine proteases activated by intracellular Ca2+. Although calpains mainly exist in the cytosol, calpain-13 is present in the mitochondria in mouse brains; however, the enzymatic properties and physiological functions
Externí odkaz:
https://doaj.org/article/cb4e0189b01a440aa8d0588b56e8c5da
Autor:
Himari Matsusaka, Tao Wu, Kai Furuya, Tomoe Yamada-Kato, Lanlan Bai, Hiroshi Tomita, Eriko Sugano, Taku Ozaki, Tohru Kiyono, Isao Okunishi, Tomokazu Fukuda
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-7 (2022)
Measurement(s) androgen receptor signaling pathway Technology Type(s) Next Generation Sequencing Sample Characteristic - Organism Homo
Externí odkaz:
https://doaj.org/article/34e969c7942542768be873cb876acca7
Autor:
Yuya Takita, Eriko Sugano, Kazuya Kitabayashi, Kitako Tabata, Akito Saito, Takanori Yokoyama, Reina Onoguchi, Tomokazu Fukuda, Taku Ozaki, Lanlan Bai, Hiroshi Tomita
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16433 (2023)
Electroretinograms (ERGs) are often used to evaluate retinal function. However, assessing local retinal function can be challenging; therefore, photopic and scotopic ERGs are used to record whole-retinal function. This study evaluated focal retinal f
Externí odkaz:
https://doaj.org/article/4adf324a0a7b431588a207e45986ab0f
Autor:
Ginga Ito, Yota Tatara, Ken Itoh, Miwa Yamada, Tetsuro Yamashita, Kimitoshi Sakamoto, Takayuki Nozaki, Kinji Ishida, Yui Wake, Takehito Kaneko, Tomokazu Fukuda, Eriko Sugano, Hiroshi Tomita, Taku Ozaki
Publikováno v:
BBA Advances, Vol 3, Iss , Pp 100092- (2023)
Glycation, caused by reactive dicarbonyls, plays a role in various diseases by forming advanced glycation end products. In live cells, reactive dicarbonyls such as glyoxal (GO) and methylglyoxal (MGO) are produced during cell metabolism, and these sh
Externí odkaz:
https://doaj.org/article/38dd74381caa491fa5a7caaa4eb4330e
Autor:
Yoshito Watanabe, Eriko Sugano, Kitako Tabata, Akito Hatakeyama, Tetsuya Sakajiri, Tomokazu Fukuda, Taku Ozaki, Tomoya Suzuki, Tatsuki Sayama, Hiroshi Tomita
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract Optogenetic gene-mediated therapy for restoring vision is thought to be a useful treatment for blind patients. However, light sensitivity achieved using this gene therapy is inferior to that of daylight vision. To increase light sensitivity,
Externí odkaz:
https://doaj.org/article/3eded4829cbb45888bc6743b0a9ac6ec
Autor:
Akito Hatakeyama, Eriko Sugano, Tatsuki Sayama, Yoshito Watanabe, Tomoya Suzuki, Kitako Tabata, Yuka Endo, Tetsuya Sakajiri, Tomokazu Fukuda, Taku Ozaki, Hiroshi Tomita
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 5054 (2023)
Channelrhodopsins have been utilized in gene therapy to restore vision in patients with retinitis pigmentosa and their channel kinetics are an important factor to consider in such applications. We investigated the channel kinetics of ComV1 variants w
Externí odkaz:
https://doaj.org/article/5c45715e7ae54aad80de880fd88bafe8
Publikováno v:
Biochemistry and Biophysics Reports, Vol 27, Iss , Pp 101101- (2021)
Calpains are Ca2+-dependent cysteine proteases; their aberrant activation is associated with several neurodegenerative diseases. The μ-calpain catalytic subunit, calpain-1, is located in the cytoplasm as well as in the mitochondria. Mitochondrial ca
Externí odkaz:
https://doaj.org/article/c77f68871d3f4cae8ec1e0a917ae6f2f
Autor:
Yuki Kikuchi, Eriko Sugano, Shiori Yuki, Kitako Tabata, Yuka Endo, Yuya Takita, Reina Onoguchi, Taku Ozaki, Tomokazu Fukuda, Yoshihiro Takai, Takahiro Kurose, Koichi Tanaka, Yoichi Honma, Eduardo Perez, Maxwell Stock, José R. Fernández, Masanori Tamura, Michael Voronkov, Jeffry B. Stock, Hiroshi Tomita
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8802 (2022)
Age-related macular degeneration is a progressive retinal disease that is associated with factors such as oxidative stress and inflammation. In this study, we evaluated the protective effects of SIG-1451, a non-steroidal anti-inflammatory compound de
Externí odkaz:
https://doaj.org/article/ab3e2b4ec5064c70809809faf75448a0
Autor:
Jun Liu, Shuya Kasai, Yota Tatara, Hiromi Yamazaki, Junsei Mimura, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Tsubasa Sato, Taku Ozaki, Kunikazu Tanji, Koichi Wakabayashi, Hayato Maeda, Hiroki Mizukami, Yasuhiro Shinkai, Yoshito Kumagai, Hirofumi Tomita, Ken Itoh
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3201 (2022)
GCN1 is an evolutionarily-conserved ribosome-binding protein that mediates the amino acid starvation response as well as the ribotoxic stress response. We previously demonstrated that Gcn1 mutant mice lacking the GCN2-binding domain suffer from growt
Externí odkaz:
https://doaj.org/article/8e518720faf048c0ba956cdf00949372