Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Taku Murata"'
Autor:
Gaku Koizumi DDS, Akinobu Hayashi MD, PhD, Akira Takigawa DDS, Rina Yamada DDS, Taku Murata DDS, PhD, Kasumi Shimizu DDS, PhD, Masatoshi Watanabe MD, PhD, Naoya Arai DDS, PhD
Publikováno v:
Journal of Investigative Medicine High Impact Case Reports, Vol 12 (2024)
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) occurs in the jawbone and interfacing oral mucosa of patients treated with bisphosphonates. Herein, we report novel histopathological findings in the oral mucosa of a surgical specimen obtained
Externí odkaz:
https://doaj.org/article/acf4b50e41404b92bf84eba742df5150
Autor:
Kazuto Kurohara, Kasumi Shimizu, Taku Murata, Gaku Koizumi, Akira Takigawa, Kokoro Nagata, Kenya Okumura, Naoya Arai
Publikováno v:
Diagnostics, Vol 12, Iss 8, p 1836 (2022)
Antiresorptive agent-related osteonecrosis of the jaw (ARONJ), a multifactorial disease, can drastically affect a patient’s quality of life. Moreover, disease progression to severe acute inflammation can hinder treatment. Therefore, we aimed to inv
Externí odkaz:
https://doaj.org/article/d0e0f867188642bdbf10deef37a55489
Publikováno v:
Anticancer Research. 39:6057-6062
Background/aim The prognosis of patients with osteosarcoma is poor; therefore, new treatment strategies are urgently needed. Phosphodiesterase 2 (PDE2) is one of the 11 families (PDE1-PDE11) of the phosphodiesterase superfamily that regulates the int
Publikováno v:
Anticancer Research. 38:6715-6720
Background/aim Due to its abilities of substance adsorption and intracellular transportation, hydroxyapatite is a potential carrier in drug delivery systems (DDS). This in vitro study investigated whether newly-developed, highly-dispersive calcined h
Autor:
Naoya Arai, Hiroshi Morita, Taku Murata, Kenichi Hiramoto, Kasumi Shimizu, Toshiro Tagawa, Madoka Inui, Vincent C. Manganiello
Publikováno v:
Cellular Signalling. 26:1807-1817
Cyclic nucleotide phosphodiesterases (PDEs) regulate the intracellular concentrations and effects of adenosine 3′,5′-cyclic monophosphate (cAMP) and guanosine 3′,5′-cyclic monophosphate (cGMP). The role of PDEs in malignant tumor cells is sti
Publikováno v:
Asian Journal of Oral and Maxillofacial Surgery. 19:222-225
Xeroderma pigmentosum is a rare, autosomal recessive genetic disease accompanied by abnormal DNA function due to damage by ultraviolet radiation. Xeroderma pigmentosum typically has general features of high light sensitivity and a high incidence of s
Autor:
C Sato, K Mine, Taku Murata, Toshiyuki Nakagawa, Takeo Sugiyama, Kasumi Shimizu, T. Tagawa, T Fujii
Publikováno v:
Oral Diseases. 13:228-233
Objective: To evaluate the effects of various 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) on ectopic osteoinduction by recombinant human bone morphogenetic protein-2 (rhBMP-2) using different administration methods. Materials
Autor:
Takeo Sugiyama, Kenichi Hiramoto, Toshiyuki Nakagawa, Toshiro Tagawa, Taku Murata, Kasumi Shimizu, Vincent C. Manganiello
Publikováno v:
Archives of Oral Biology. 51:83-88
Phosphodiesterase (PDE) 3 has been characterized in isolated rat submandibular acini. PDE3 activity was detected in homogenates of isolated rat submandibular acini; little or no PDE3 activity was found in ducts. About 62% of PDE3 activity in the acin
Autor:
Kasumi Shimizu, T. Tagawa, M Narita, Takeo Sugiyama, Toshiyuki Nakagawa, Taku Murata, Shinnosuke Nakamura
Publikováno v:
Oral Diseases. 9:255-263
Objective: To investigate the characteristics of ectopic chondroid/bone matrix and chondrogenic/osteogenic cells induced by recombinant human bone morphogenetic protein-2 (rhBMP-2). Materials and methods: rhBMP-2 (5 μg) combined with atelocollagen w
Autor:
Takeo Sugiyama, Vincent C. Manganiello, Kasumi Shimizu, Taku Murata, Motoshi Narita, Toshiro Tagawa, Toshiyuki Nakagawa
Publikováno v:
Anti-Cancer Drugs. 14:377-381
Reverse transcription-polymerase chain reaction (RT-PCR) analysis revealed that HOSM-1 cells, an osteosarcoma cell line established from human mandible, expressed mRNA for osteoblastic markers, such as alkaline phosphatase, osteonectin, osteocalcin a