Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Taku Kaitsuka"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2021)
Several variant proteins are produced from EEF1D, including two representative proteins produced via alternative splicing machinery. One protein is the canonical translation eukaryotic elongation factor eEF1Bδ1, and the other is the heat shock-respo
Externí odkaz:
https://doaj.org/article/5428aadfb5fc4109af4e5c42e56df1ed
Autor:
Md Fakruddin, Fan-Yan Wei, Takeo Suzuki, Kana Asano, Takashi Kaieda, Akiko Omori, Ryoma Izumi, Atsushi Fujimura, Taku Kaitsuka, Keishi Miyata, Kimi Araki, Yuichi Oike, Luca Scorrano, Tsutomu Suzuki, Kazuhito Tomizawa
Publikováno v:
Cell Reports, Vol 22, Iss 2, Pp 482-496 (2018)
Summary: A subset of mitochondrial tRNAs (mt-tRNAs) contains taurine-derived modifications at 34U of the anticodon. Loss of taurine modification has been linked to the development of mitochondrial diseases, but the molecular mechanism is still unclea
Externí odkaz:
https://doaj.org/article/3ea53816cd4e483b935a075495344241
Publikováno v:
Cells, Vol 10, Iss 12, p 3316 (2021)
The sirtuin family of nicotinamide adenine dinucleotide-dependent deacetylase and ADP-ribosyl transferases plays key roles in aging, metabolism, stress response, and aging-related diseases. SIRT2 is a unique sirtuin that is expressed in the cytosol a
Externí odkaz:
https://doaj.org/article/4e2f4a1a343549b6ba8f333f3ff51c93
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Alternative splicing enables a gene to give rise to diverse protein products. The Eef1d gene produces two isoforms: a short isoform that encodes translation elongation factor 1Bδ (eEF1Bδ1), and a long isoform that encodes the heat shock-responsive
Externí odkaz:
https://doaj.org/article/58be8c016c014c90b9b51b2bf81cbda3
Autor:
Taku Kaitsuka, Farzana Hakim
Publikováno v:
Biology, Vol 10, Iss 2, p 84 (2021)
Pluripotent stem cells have unique characteristics compared to somatic cells. In this review, we summarize the response to environmental stresses (hypoxic, oxidative, thermal, and mechanical stresses) in embryonic stem cells (ESCs) and their applicat
Externí odkaz:
https://doaj.org/article/0857e7d4a7c34c318b7c80400546eb89
Autor:
Taku Kaitsuka, Kazuhito Tomizawa
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 11, Pp 26667-26676 (2015)
Protein transduction using cell-penetrating peptides (CPPs) is useful for the delivery of large protein molecules, including some transcription factors. This method is safer than gene transfection methods with a viral vector because there is no risk
Externí odkaz:
https://doaj.org/article/11af14102b034af0b1df9aa02df16102
Publikováno v:
Cells, Vol 9, Iss 3, p 620 (2020)
Regenerative medicine and disease modeling are expanding rapidly, through the development of human-induced pluripotent stem cells (hiPSCs). Many exogeneous supplements are often used for the directed differentiation of hiPSCs to specific lineages, su
Externí odkaz:
https://doaj.org/article/b9481ad1f6654ce7b97c9c8365bcd5ae
Autor:
Taku Kaitsuka, Masayuki Matsushita
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 2, Pp 3970-3979 (2015)
Alternative splicing is an exquisite mechanism that allows one coding gene to have multiple functions. The alternative splicing machinery is necessary for proper development, differentiation and stress responses in a variety of organisms, and disrupt
Externí odkaz:
https://doaj.org/article/5fd1dc6e768042e2864b78458ff311aa
Autor:
Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006355 (2016)
Reversible infantile liver failure (RILF) is a unique heritable liver disease characterized by acute liver failure followed by spontaneous recovery at an early stage of life. Genetic mutations in MTU1 have been identified in RILF patients. MTU1 is a
Externí odkaz:
https://doaj.org/article/93f732f5c91e411a9053a7be405206e9
Autor:
Hiroki Takeda, Takaomi Kurioka, Taku Kaitsuka, Kazuhito Tomizawa, Takeshi Matsunobu, Farzana Hakim, Kunio Mizutari, Toru Miwa, Takao Yamada, Momoko Ise, Akihiro Shiotani, Eiji Yumoto, Ryosei Minoda
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Cell-penetrating peptides (CPPs) are short sequences of amino acids that facilitate the penetration of conjugated cargoes across mammalian cell membranes, and as such, they may provide a safe and effective method for drug delivery to the inner ear. S
Externí odkaz:
https://doaj.org/article/25b6b285174a4456bf9226eba0c78491