Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Taku Kaitsuka"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2021)
Several variant proteins are produced from EEF1D, including two representative proteins produced via alternative splicing machinery. One protein is the canonical translation eukaryotic elongation factor eEF1Bδ1, and the other is the heat shock-respo
Externí odkaz:
https://doaj.org/article/5428aadfb5fc4109af4e5c42e56df1ed
Autor:
Md Fakruddin, Fan-Yan Wei, Takeo Suzuki, Kana Asano, Takashi Kaieda, Akiko Omori, Ryoma Izumi, Atsushi Fujimura, Taku Kaitsuka, Keishi Miyata, Kimi Araki, Yuichi Oike, Luca Scorrano, Tsutomu Suzuki, Kazuhito Tomizawa
Publikováno v:
Cell Reports, Vol 22, Iss 2, Pp 482-496 (2018)
Summary: A subset of mitochondrial tRNAs (mt-tRNAs) contains taurine-derived modifications at 34U of the anticodon. Loss of taurine modification has been linked to the development of mitochondrial diseases, but the molecular mechanism is still unclea
Externí odkaz:
https://doaj.org/article/3ea53816cd4e483b935a075495344241
Publikováno v:
Cells, Vol 10, Iss 12, p 3316 (2021)
The sirtuin family of nicotinamide adenine dinucleotide-dependent deacetylase and ADP-ribosyl transferases plays key roles in aging, metabolism, stress response, and aging-related diseases. SIRT2 is a unique sirtuin that is expressed in the cytosol a
Externí odkaz:
https://doaj.org/article/4e2f4a1a343549b6ba8f333f3ff51c93
Autor:
Taku Kaitsuka, Farzana Hakim
Publikováno v:
Biology, Vol 10, Iss 2, p 84 (2021)
Pluripotent stem cells have unique characteristics compared to somatic cells. In this review, we summarize the response to environmental stresses (hypoxic, oxidative, thermal, and mechanical stresses) in embryonic stem cells (ESCs) and their applicat
Externí odkaz:
https://doaj.org/article/0857e7d4a7c34c318b7c80400546eb89
Publikováno v:
Cells, Vol 9, Iss 3, p 620 (2020)
Regenerative medicine and disease modeling are expanding rapidly, through the development of human-induced pluripotent stem cells (hiPSCs). Many exogeneous supplements are often used for the directed differentiation of hiPSCs to specific lineages, su
Externí odkaz:
https://doaj.org/article/b9481ad1f6654ce7b97c9c8365bcd5ae
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Alternative splicing enables a gene to give rise to diverse protein products. The Eef1d gene produces two isoforms: a short isoform that encodes translation elongation factor 1Bδ (eEF1Bδ1), and a long isoform that encodes the heat shock-responsive
Externí odkaz:
https://doaj.org/article/58be8c016c014c90b9b51b2bf81cbda3
Autor:
Sheng-Lan Shi, Hiroyuki Fukuda, Mayumi Hirayama, Kazuhito Tomizawa, Hiroyuki Oshiumi, Fan-Yan Wei, Takahiro Yamamoto, Takeshi Chujo, Taku Kaitsuka
Publikováno v:
Nucleic Acids Research
Retroviral infection requires reverse transcription, and the reverse transcriptase (RT) uses cellular tRNA as its primer. In humans, the TRMT6-TRMT61A methyltransferase complex incorporates N1-methyladenosine modification at tRNA position 58 (m1A58);
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52054e2351b7e972f44783004b184e50
https://doi.org/10.1093/nar/gkab879
https://doi.org/10.1093/nar/gkab879
Autor:
Tetyana Zhelay, J. Ashot Kozak, Jananie Rockwood, Pavani Beesetty, Siham Hourani, Masayuki Matsushita, Taku Kaitsuka
Publikováno v:
FEBS J
Transient receptor potential melastatin 7 (TRPM7) is a unique protein functioning as a cation channel as well as a serine/threonine kinase and is highly expressed in immune cells such as lymphocytes and macrophages. TRPM7 kinase-dead (KD) mouse model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca4d89b061b82f6a2b4c3a531447454
https://doi.org/10.1111/febs.15683
https://doi.org/10.1111/febs.15683
Autor:
Mizuki Goto, Takumi Era, Yorifumi Satou, Taku Kaitsuka, Tomoya Matsusako, Yoshikazu Uchiyama, Kazuhito Tomizawa, Tomohiro Sawa, Kazuaki Monde, Yosuke Maeda, Fan Yan Wei, Shinya Yamaga, Jumpei Ito, Hiromi Terasawa, Akira Ono, Ituro Inoue
Publikováno v:
Journal of Virology. 96
SummaryHuman endogenous retroviruses (HERVs) occupy approximately 8% of human genome. HERVs, which are transcribed in early embryos, are epigenetically silenced in somatic cells, except in pathological contexts. HERV-K is thought to protect the embry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1c786dfd782d6dc5dfc4eddb4bc6b7
https://doi.org/10.1128/jvi.00356-22
https://doi.org/10.1128/jvi.00356-22
Autor:
Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006355 (2016)
Reversible infantile liver failure (RILF) is a unique heritable liver disease characterized by acute liver failure followed by spontaneous recovery at an early stage of life. Genetic mutations in MTU1 have been identified in RILF patients. MTU1 is a
Externí odkaz:
https://doaj.org/article/93f732f5c91e411a9053a7be405206e9