Transcript-specific enrichment enables profiling rare cell states via scRNA-seq.

Autor: Abay T; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA.; Department of Pathology, Stanford University, Stanford CA, USA.; Program in Biological and Biomedical Sciences, Harvard University, Boston, MA, USA., Stickels RR; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA.; Department of Pathology, Stanford University, Stanford CA, USA., Takizawa MT; Single-cell Analytics Innovation Lab, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Nalbant BN; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hsieh YH; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Charité Universitätsmedizin Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany., Hwang S; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA.; Department of Pathology, Stanford University, Stanford CA, USA., Snopkowski C; Single-cell Analytics Innovation Lab, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Yu KKH; Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Abou-Mrad Z; Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Tabar V; Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ludwig LS; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany., Chaligné R; Single-cell Analytics Innovation Lab, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Satpathy AT; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA.; Department of Pathology, Stanford University, Stanford CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA., Lareau CA; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Mar 27. Date of Electronic Publication: 2024 Mar 27.