The Role of the Placental Enzyme Indoleamine 2,3-Dioxygenase in Normal and Abnormal Human Pregnancy.

Autor: Kudo, Yoshiki¹ (AUTHOR) juns@hiroshima-u.ac.jp, Sugimoto, Jun¹ (AUTHOR)

Publikováno v: International Journal of Molecular Sciences. Apr2024, Vol. 25 Issue 8, p4577. 12p.

Identification and Characterization of a Novel Dual Inhibitor of Indoleamine 2,3-dioxygenase 1 and Tryptophan 2,3-dioxygenase.

Autor: Yoshioka S; Center for Drug Discovery, Graduate School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan., Ikeda T; Center for Drug Discovery, Graduate School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan., Fukuchi S; Center for Drug Discovery, Graduate School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan., Kawai Y; Center for Drug Discovery, Graduate School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan., Ohta K; Center for Drug Discovery, Graduate School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan., Murakami H; Center for Drug Discovery, Graduate School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan., Ogo N; Center for Drug Discovery, Graduate School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan., Muraoka D; Department of Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Takikawa O; National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Aichi, Japan., Asai A; Center for Drug Discovery, Graduate School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.

Publikováno v: International journal of tryptophan research : IJTR [Int J Tryptophan Res] 2022 Nov 30; Vol. 15, pp. 11786469221138456. Date of Electronic Publication: 2022 Nov 30 (Print Publication: 2022).

Redefining Roles: A Paradigm Shift in Tryptophan–Kynurenine Metabolism for Innovative Clinical Applications.

Autor: Tanaka, Masaru¹ (AUTHOR) tanaka.masaru.1@med.u-szeged.hu, Szabó, Ágnes^2,3 (AUTHOR) szabo.agnes.4@med.u-szeged.hu, Vécsei, László^1,2 (AUTHOR) tanaka.masaru.1@med.u-szeged.hu

Publikováno v: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 23, p12767. 45p.

Alzheimer's disease-specific transcriptomic and epigenomic changes in the tryptophan catabolic pathway.

Autor: Choe, Kyonghwan¹ (AUTHOR), Ali, Muhammad^1,2,3 (AUTHOR), Lardenoije, Roy^1,4 (AUTHOR), Riemens, Renzo J.M.¹ (AUTHOR), Pishva, Ehsan^1,5 (AUTHOR), Bickel, Horst⁶ (AUTHOR), Weyerer, Siegfried⁷ (AUTHOR), Hoffmann, Per^8,9,10 (AUTHOR), Pentzek, Michael¹¹ (AUTHOR), Riedel-Heller, Steffi¹² (AUTHOR), Wiese, Birgitt¹³ (AUTHOR), Scherer, Martin¹⁴ (AUTHOR), Wagner, Michael^15,16 (AUTHOR), Mastroeni, Diego^1,17,18 (AUTHOR), Coleman, Paul D.¹⁸ (AUTHOR), Ramirez, Alfredo^{15,16,19,20,21} (AUTHOR), Ramakers, Inez H.G.B.^1,22 (AUTHOR), Verhey, Frans R.J.^1,22 (AUTHOR), Rutten, Bart P.F.¹ (AUTHOR), Kenis, Gunter¹ (AUTHOR)

Publikováno v: Alzheimer's Research & Therapy. 11/30/2024, Vol. 16 Issue 1, p1-16. 16p.

From Microcirculation to Aging-Related Diseases: A Focus on Endothelial SIRT1.

Autor: Law, Martin¹ (AUTHOR) martinlaw9770@gmail.com, Wang, Pei-Chun^1,2 (AUTHOR), Zhou, Zhong-Yan^1,2,3 (AUTHOR) biozzy@126.com, Wang, Yu^1,2 (AUTHOR) biozzy@126.com

Publikováno v: Pharmaceuticals (14248247). Nov2024, Vol. 17 Issue 11, p1495. 26p.