Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Taketoshi Saijo"'
Autor:
Takao Ando, Shuzo Sato, Kenichi Kanamaru, Satoshi Sasaki, Takayasu Ito, Shinji Sugimoto, Taketoshi Saijo, Ryoetsu Imai, Miho Imawaka
Publikováno v:
The Journal of Toxicological Sciences. 22:315-325
A procedure for recording the electroretinogram (ERG) in pigmented mice, C57BL, based on the ERG recording technique reported previously in albino mice, ICR, and giving careful consideration to the influence of anesthetics and dark-adaptation, was de
Autor:
Taketoshi Saijo, Hiroaki Miyajima
Publikováno v:
Journal of Toxicologic Pathology. 8:245-256
Immunotoxicology has become a very important field because of the immunological adverse effects of various cytokines (IL-2 and IFNα, etc.) and biological response modifiers in addition to the immunosuppression caused by steroid hormones and anticanc
Autor:
Shuzo Sato, Takayasu Ito, Shinji Sugimoto, Taketoshi Saijo, Kenichi Kanamaru, Kazuyuki Kurata, Takao Ando, Satoshi Sasaki, Miho Imawaka
Publikováno v:
The Journal of toxicological sciences. 21
A procedure for recording the electroretinogram (ERG) in mice with a coiled stainless steel-type electrode was developed in order to examine retinal toxicity. Mice received a single i.v. of sodium iodate (SI), a retinotoxic compound, via the tail vei
Publikováno v:
Immunopharmacology. 19(3)
By flow cytometric analysis, we identified the subclass of lymphocytes that proliferates in response to islet-activating protein (IAP), both in vitro (human peripheral blood mononuclear cells, MNC, cultured with IAP) and in vivo (peripheral blood MNC
Publikováno v:
Annals of the New York Academy of Sciences. 629:394-395
Autor:
Taketoshi Saijo, Hisashi Kuriki, Yasushi Sanno, Kiyoshi Ukawa, Toshihiro Ishiguro, Akira Nohara, Yoshitaka Maki
Publikováno v:
Journal of Medicinal Chemistry. 22:290-295
The metabolites of 6-ethyl-3-(1H-tetrazol-5-yl)chromone (AA-344) (1), an orally effective antiallergic agent, and their analogues were synthesized to confirm the proposed structures and to determine their activity in the rat passive cutaneous anaphyl
Publikováno v:
Agents and Actions. 28:248-255
AA-2379 (methyl 7-butyl-4,5,6,7-tetrahydro-3-methylamino-4,6-dioxo-5-propyl- 2H-pyrazolo [3,4-d]pyrimidine-2-carboxylate) has antiinflammatory, analgesic, and antipyretic activities, and inhibits the type III allergic (Arthus) reaction. In the studie
Publikováno v:
International Archives of Allergy and Immunology. 79:38-44
In studies of the role of leukotrienes in inflammatory reactions, the induction of rat reversed passive Arthus pleurisy (a type III allergic reaction) was employed. Increases of exudate volume, vascular permeability, and migration of inflammatory cel
Autor:
Taketoshi Saijo, S. Terao, Yasuko Ashida, Haruhiko Makino, S. Tamura, Hisashi Kuriki, Yoshitaka Maki
Publikováno v:
International Archives of Allergy and Immunology. 79:231-237
Amoxanox has potent antiallergic activity because it inhibits the release of chemical mediators such as histamine and leukotrienes. We studied the in vitro effect of amoxanox on arachidonic acid metabolism, including the lipoxygenase and cyclooxygena
Publikováno v:
Japanese Journal of Pharmacology. 29:531-540
The antiallergic action of 6-ethyl-3-(1H-tetrazol-5-yl)chromone (AA-344) was studied on isolated rat peritoneal mast cells. AA-344 clearly inhibited the IgE-mediated release of histamine caused by various concentrations of antigen and the 50% inhibit