Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Taketoshi Ishii"'
Autor:
Yumi Watanabe, Masahito Okamoto, Taketoshi Ishii, Satomi Takatsuka, Hiroyuki Taniguchi, Masaaki Nagasaki, Akira Saito
Publikováno v:
Journal of Pharmacological Sciences, Vol 107, Iss 2, Pp 151-158 (2008)
The effect of T-2328 {2-fluoro-4’-methoxy-3’-[[[(2S,3S)-2-phenyl-3-piperidinyl] amino]methyl]-[1,1’-biphenyl]-4-carbonitrile dihydrochloride}, a novel tachykinin NK1–receptor antagonist, was examined on cisplatin-induced emesis in ferrets. Ci
Externí odkaz:
https://doaj.org/article/ec753531074f40da839cd737a8890aaf
Autor:
Yumi Watanabe, Hidetoshi Asai, Taketoshi Ishii, Satoko Kiuchi, Masahito Okamoto, Hiroyuki Taniguchi, Masaaki Nagasaki, Akira Saito
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 1, Pp 121-127 (2008)
The pharmacological properties of T-2328 were evaluated as an antagonist of the tachykinin neurokinin 1 (NK1) receptor. T-2328 inhibited the specific binding of [3H][Sar9,Met(O2)11]substance P to tachykinin NK1receptors in human lymphoblastic IM9 cel
Externí odkaz:
https://doaj.org/article/f30a930dcd534001a2fd08e71107e8a3
Autor:
Hiroyuki Taniguchi, Taketoshi Ishii, Yumi Watanabe, Jun Kotera, Misae Takakuwa, Kiichi Tanaka, Kenji Hashimoto, Kenta Kagaya
Publikováno v:
Pharmacology Biochemistry and Behavior. 185:172757
Phosphodiesterase (PDE) 10A is an attractive therapeutic target for schizophrenia. Here, we investigated the antipsychotic-like effects of a novel PDE10A inhibitor, 1-({2-(7-fluoro-3-methylquinoxalin-2-yl)-5-[(3R)-3-fluoropyrrolidin-1-yl]pyrazolo[1,5
Publikováno v:
Japanese Journal of Pharmacology. 83:119-124
Autor:
Satomi Takatsuka, Hiroyuki Taniguchi, Masaaki Nagasaki, Akira Saito, Yumi Watanabe, Taketoshi Ishii, Masahito Okamoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 107, Iss 2, Pp 151-158 (2008)
The effect of T-2328 {2-fluoro-4’-methoxy-3’-[[[(2S,3S)-2-phenyl-3-piperidinyl] amino]methyl]-[1,1’-biphenyl]-4-carbonitrile dihydrochloride}, a novel tachykinin NK1–receptor antagonist, was examined on cisplatin-induced emesis in ferrets. Ci
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 131(3)
片頭痛は頭痛発作を繰り返す疾患であり,本邦では人口の8.4%に存在する.男性に比べて女性での発症率のほうが高く,症状は悪心および嘔吐を伴うことが多い.痛みは激烈で,日常生活
Autor:
Masaaki Nagasaki, Taketoshi Ishii, Masahito Okamoto, Satoko Kiuchi, Akira Saito, Hiroyuki Taniguchi, Yumi Watanabe, Hidetoshi Asai
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 1, Pp 121-127 (2008)
The pharmacological properties of T-2328 were evaluated as an antagonist of the tachykinin neurokinin 1 (NK1) receptor. T-2328 inhibited the specific binding of [3H][Sar9,Met(O2)11]substance P to tachykinin NK1receptors in human lymphoblastic IM9 cel
Publikováno v:
Biologicalpharmaceutical bulletin. 23(4)
The present investigation was conducted to examine whether a reversible inhibitor of monoamine oxidase (MAO)-A, T-794, affects the shuttle-box escape deficit induced by transient middle cerebral artery (MCA) occlusion (MCAO). MCA-occluded and sham-op
Publikováno v:
Japanese Journal of Pharmacology. 76:98
Publikováno v:
Japanese Journal of Pharmacology. 61:286