Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Taketoshi, Kajimoto"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract The insulin-like growth factor II/mannose 6-phosphate (IGF-II/M6P) receptor is a multifunctional glycoprotein not only play roles in IGF-II degradation and pro-TGFβ activation but binding to and transport M6P-bearing lysosomal enzymes from
Externí odkaz:
https://doaj.org/article/ffdd742922a049158cafb4656a97caee
Autor:
Soma Noguchi, Taketoshi Kajimoto, Takuya Kumamoto, Masashi Shingai, Soshi Narasaki, Tomoaki Urabe, Serika Imamura, Kana Harada, Izumi Hide, Sigeru Tanaka, Yuhki Yanase, Shun-Ichi Nakamura, Yasuo M. Tsutsumi, Norio Sakai
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background and purpose: In this study, we aimed to elucidate the action mechanisms of propofol, particularly those underlying propofol-induced protein kinase C (PKC) translocation.Experimental approach: Various PKCs fused with green fluorescent prote
Externí odkaz:
https://doaj.org/article/6905b40dd76244c5a441fae6f3e08a09
Autor:
Taro Okada, Susumu Nishida, Lifang Zhang, Nesma Nabil Ibrahim Mohamed, Tianyou Wang, Takeshi Ijuin, Taketoshi Kajimoto, Shun-Ichi Nakamura
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103351- (2021)
Summary: The importance of the G-protein βγ subunits in the regulation of cargo transport from the trans-Golgi network (TGN) to the plasma membrane (PM) is well accepted; however, the molecular mechanism underlying the G-protein activation at the T
Externí odkaz:
https://doaj.org/article/75eaec608d4b498a8de513a8224e8905
Autor:
Taketoshi Kajimoto, Shun-ichi Nakamura
Publikováno v:
Bio-Protocol, Vol 8, Iss 24 (2018)
Function of extracellular vesicles such as exosomes and microvesicles is determined by their wide ranges of cargoes inside them. Even in the pure exosomes or microvesicles the cargo contents are very heterogeneous. To understand this heterogeneous na
Externí odkaz:
https://doaj.org/article/3e62c1aaf0e14c30862ed60f977fdd39
Autor:
Soshi Narasaki, Soma Noguchi, Tomoaki Urabe, Kana Harada, Izumi Hide, Shigeru Tanaka, Yuki Yanase, Taketoshi Kajimoto, Kazue Uchida, Yasuo M. Tsutsumi, Norio Sakai
Publikováno v:
European Journal of Pharmacology. :175806
Autor:
Qiang Chang, Jing Yang, Jeff H. Tsai, Alexandra C. Newton, Hae-Yun Jung, Laurent Fattet, Taketoshi Kajimoto
Publikováno v:
Nature cell biology
Loss of apical-basal polarity and activation of epithelial-mesenchymal transition (EMT) both contribute to carcinoma progression and metastasis. Here, we report that apical-basal polarity inhibits EMT to suppress metastatic dissemination. Using mouse
Autor:
Shubi Ambwene, Matovelo, Lifang, Zhang, Nesma Nabil Ibrahim, Mohamed, Taketoshi, Kajimoto, Takeshi, Ijuin, Taro, Okada, Shun-Ichi, Nakamura
Publikováno v:
Kobe J Med Sci
Macropinocytosis is a highly conserved cellular process of endocytosis by which extracellular fluid and nutrients are taken up into cells through large, heterogeneous vesicles known as macropinosomes. Growth factors such as epidermal growth factor (E
Autor:
Soma Noguchi, Taketoshi Kajimoto, Tomoaki Urabe, Yuki Yanase, Soshi Narasaki, Kana Harada, Shigeru Tanaka, Izumi Hide, Norio Sakai
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:3
Autor:
Soshi Narasnarasaki, Soma Noguchi, Tomoaki Urabe, Kana Harada, Izumi Hide, Sigeru Tanaka, Yuki Yanase, Taketoshi Kajimoto, Norio Sakai
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:3
Autor:
Taro Okada, Shaymaa Mohamed Mohamed Badawy, Taketoshi Kajimoto, Shun-ichi Nakamura, Shunsuke Nakamura, Shubi Ambwene Matovelo, Mitsuhiro Hirase, Takeshi Ijuin, Daisuke Yoshida
Publikováno v:
Journal of Biological Chemistry. 293(21):8208-8216
α-Synuclein (α-Syn)-positive intracytoplasmic inclusions, known as Lewy bodies, are thought to be involved in the pathogenesis of Lewy body diseases, such as Parkinson's disease (PD). Although growing evidence suggests that cell-to-cell transmissio