Výsledky vyhledávání - "Takeshita, Tamotsu"

Akademický článek

Lysozyme M deficiency leads to an increased susceptibility to Streptococcus pneumoniae-induced otitis media

Autor: Woo Jeong-Im, Pan Huiqi, Takeshita Tamotsu, Lee Haa-Yung, Moon Sung K, Shimada Jun, Gellibolian Robert, Yamanaka Noboru, Lim David J

Publikováno v: BMC Infectious Diseases, Vol 8, Iss 1, p 134 (2008)

Abstract Background Lysozyme is an antimicrobial innate immune molecule degrading peptidoglycan of the bacterial cell wall. Lysozyme shows the ubiquitous expression in wide varieties of species and tissues including the tubotympanum of mammals. We ai

Externí odkaz: https://doaj.org/article/45be79018a82453bb4cc5cf4c654ca96

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Akademický článek

Induction of beta defensin 2 by NTHi requires TLR2 mediated MyD88 and IRAK-TRAF6-p38MAPK signaling pathway in human middle ear epithelial cells

Autor: Park Rae-Kil, Andalibi Ali, Moon Sung K, Pan Huiqi, Woo Jeong-Im, Akopyan Arsen, Shimada Jun, Takeshita Tamotsu, Lee Haa-Yung, Kang Sung-Ho, Kang Shin-Seok, Gellibolian Robert, Lim David J

Publikováno v: BMC Infectious Diseases, Vol 8, Iss 1, p 87 (2008)

Abstract Background All mucosal epithelia, including those of the tubotympanium, are secreting a variety of antimicrobial innate immune molecules (AIIMs). In our previous study, we showed the bactericidal/bacteriostatic functions of AIIMs against var

Externí odkaz: https://doaj.org/article/f103186ef3644db9b7d1b4e7ac8c73eb

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Akademický článek

Synergistic effect of interleukin 1 alpha on nontypeable Haemophilus influenzae-induced up-regulation of human beta-defensin 2 in middle ear epithelial cells

Autor: Park Raekil, Takeshita Tamotsu, Pan Huiqi, Lee Haa-Yung, Moon Sung-Kyun, Cha Kiweon, Andalibi Ali, Lim David J

Publikováno v: BMC Infectious Diseases, Vol 6, Iss 1, p 12 (2006)

Abstract Background We recently showed that beta-defensins have antimicrobial activity against nontypeable Haemophilus influenzae (NTHi) and that interleukin 1 alpha (IL-1 alpha) up-regulates the transcription of beta-defensin 2 (DEFB4 according to n

Externí odkaz: https://doaj.org/article/095baa43a8794f679a9d442be742a67f

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Akademický článek

Induction of beta defensin 2 by NTHi requires TLR2 mediated MyD88 and IRAK-TRAF6-p38MAPK signaling pathway in human middle ear epithelial cells.

Autor: Haa-Yung Lee¹ hlee@hei.org, Takeshita, Tamotsu^1,2 ttake@hama-med.ac.jp, Shimada, Jun^1,3 Jasmd513@aol.com, Akopyan, Arsen¹ aakopyan@hei.org, Jeong-Im Woo¹ jwoo@hei.org, Pan, Huiqi¹ hpan@hei.org, Sung K. Moon¹ smoon@hei.org, Andalibi, Ali¹ aandalibi@hei.org, Rae-Kil Park^1,4 rkpark@wonkwang.ac.kr, Sung-Ho Kang⁵ kkdin@kku.ac.kr, Shin-Seok Kang¹ skang@hei.org, Gellibolian, Robert¹ rgellibolian@hei.org, Lim, David J.^1,6,7 dlim@hei.org

Publikováno v: BMC Infectious Diseases. 2008, Vol. 8 Issue 1, Special section p1-12. 12p. 5 Graphs.

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