Zobrazeno 1 - 10
of 758
pro vyhledávání: '"Takeshi UEHARA"'
Autor:
Hisashi Tamada, Takeshi Uehara, Takahiro Yoshizawa, Mai Iwaya, Shiho Asaka, Tomoyuki Nakajima, Masato Kamakura, Hiroyoshi Ota
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-7 (2024)
Abstract Background Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) is a cancer stem cell (CSC) marker of colorectal cancer and may be a CSC marker of other cancer types. Few studies have been conducted on LGR5 expression in extrah
Externí odkaz:
https://doaj.org/article/d0025dad0aa5448b81a650dec4b7fcc4
Autor:
Shunichiro Matsuoka, Takashi Eguchi, Mai Iwaya, Maho Seshimoto, Shuji Mishima, Daisuke Hara, Hirotaka Kumeda, Kentaro Miura, Kazutoshi Hamanaka, Takeshi Uehara, Kimihiro Shimizu
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37412- (2024)
Objectives: Spread through air spaces (STAS) is a form of lung cancer invasion that extends beyond the tumor edge and is associated with a worse prognosis. Recent advances in immunotherapy highlight the importance of understanding the tumor microenvi
Externí odkaz:
https://doaj.org/article/e599bd0ccc994c238a52b550fac729a0
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background IgG4, which plays a pivotal role in the progression of phenotypically diverse tumors, serves as a prognostic marker because of its influence on cancer immunity. Nevertheless, the functions of IgG4 in tongue squamous cell carcinoma
Externí odkaz:
https://doaj.org/article/f37ed99742e44719a56a9ef63121379e
Autor:
Kenichi Takahashi, Hirosato Mashima, Masanari Sekine, Takeshi Uehara, Takeharu Asano, Ge-Hong Sun-Wada, Yoh Wada, Hirohide Ohnishi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Rab7 is known to function in the autophagy and endocytosis pathways in eukaryocytes and is related to various diseases. We recently reported that Rab7 plays a protective role against acute pancreatitis. However, its physiological function in
Externí odkaz:
https://doaj.org/article/ea377388f56c424c87751497e8ddbd0c
Autor:
Masatoshi Shimura, Kentaro Miura, Tomonobu Koizumi, Shintaro Kanda, Shuji Mishima, Daisuke Hara, Shunichiro Matsuoka, Takashi Eguchi, Kazutoshi Hamanaka, Takeshi Uehara, Kimihiro Shimizu
Publikováno v:
Thoracic Cancer, Vol 14, Iss 17, Pp 1640-1643 (2023)
Abstract Thymic carcinoma is a highly malignant tumor and treatment options are limited. Lenvatinib, a novel multitargeted kinase inhibitor, has recently been approved for the treatment of unresectable thymic carcinoma. There are no reports of comple
Externí odkaz:
https://doaj.org/article/d9aa1498de3a44ed8dc2a72d121d7ecb
Autor:
Ryo Kanai, Takeshi Uehara, Takahiro Yoshizawa, Masato Kamakura, Tomoyuki Nakajima, Yasuhiro Kinugawa, Mai Iwaya, Shiho Asaka, Masato Kitazawa, Tadanobu Nagaya, Hiroyoshi Ota
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-6 (2023)
Abstract Background ADP-ribosylation factor-like protein 4 C (ARL4C) is a member of the ARF small GTP-binding protein subfamily. The ARL4C gene is highly expressed in colorectal cancer (CRC). ARL4C protein promotes cell motility, invasion, and prolif
Externí odkaz:
https://doaj.org/article/621662534c324aca98a24906d9ba8f72
Autor:
Fumihito Ichinohe, Daisuke Komatsu, Akira Yamada, Takanori Aonuma, Ayumi Sakai, Marika Shimizu, Masahiro Kurozumi, Akira Shimizu, Yuji Soejima, Takeshi Uehara, Yasunari Fujinaga
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 8018-8026 (2023)
Abstract Aim Using classification tree analysis, we evaluated the most useful magnetic resonance (MR) image type in the differentiation between early and progressed hepatocellular carcinoma (eHCC and pHCC). Methods We included pathologically proven 2
Externí odkaz:
https://doaj.org/article/eea797777c3340f38b447d1c99b60acb
Autor:
Akira Takazawa, Yasuo Yoshimura, Masanori Okamoto, Atsushi Tanaka, Munehisa Kito, Kaoru Aoki, Takeshi Uehara, Jun Takahashi, Hiroyuki Kato, Jun Nakayama
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Myxoid liposarcoma (MLS) is a common subtype of liposarcoma. Although the prognosis is generally good, there are factors known to be associated with poor prognosis. Accurate indices are important to predict prognosis. We aimed to assess the
Externí odkaz:
https://doaj.org/article/a8e415856e964192bc4b604985ec2c05
Autor:
Futoshi Muranaka, Emiko Kise, Shigeo Tokumaru, Masato Kitazawa, Yusuke Miyagawa, Tomoaki Suga, Takeshi Uehara, Mai Iwaya, Shota Kobayashi, Midori Sato, Daisuke Gomi, Hidetaka Yamada, Haruhiko Sugimura, Tomoki Kosho, Yuji Soejima, Tomonobu Koizumi
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract Background Germline pathogenic variants in the E-cadherin gene CDH1 cause hereditary diffuse gastric cancer (HDGC), which is an autosomal dominant cancer syndrome, accounting for 1–3% of all gastric cancers. HDGC harboring a CDH 1 variant
Externí odkaz:
https://doaj.org/article/837be0e56d4e4432902cd92cf7a9deee
Autor:
Takanobu Iwadare, Takefumi Kimura, Naoki Tanaka, Tomoo Yamazaki, Shun-ichi Wakabayashi, Taiki Okumura, Hiroyuki Kobayashi, Yuki Yamashita, Sai P. Pydi, Tomoyuki Nakajima, Mai Iwaya, Ayumi Sugiura, Satoru Joshita, Takeshi Uehara, Takeji Umemura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Among several secreted glycoproteins belonging to the thrombospondin family, thrombospondin 2 (TSP2) is involved in various functions, including collagen/fibrin formation. Liver/serum TSP2 levels have been correlated to liver fibrosis stage
Externí odkaz:
https://doaj.org/article/cbb74aa4f06742c78b5d032babd3d074