Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Takeshi Tokuyama"'
Autor:
Chika Watanabe, Hitoshi Osaka, Miyuki Watanabe, Akihiko Miyauchi, Eriko F. Jimbo, Takeshi Tokuyama, Hideki Uosaki, Yoshihito Kishita, Yasushi Okazaki, Takanori Onuki, Tomohiro Ebihara, Kenichi Aizawa, Kei Murayama, Akira Ohtake, Takanori Yamagata
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 34, Iss , Pp 100951- (2023)
Coenzyme Q10 (CoQ10) is involved in ATP production through electron transfer in the mitochondrial respiratory chain complex. CoQ10 receives electrons from respiratory chain complex I and II to become the reduced form, and then transfers electrons at
Externí odkaz:
https://doaj.org/article/3d16e4198f7d49d399b9dffcfcdfd7dc
Autor:
Takeshi Tokuyama, Hideki Uosaki, Ayumu Sugiura, Gen Nishitai, Keisuke Takeda, Shun Nagashima, Isshin Shiiba, Naoki Ito, Taku Amo, Satoshi Mohri, Akiyuki Nishimura, Motohiro Nishida, Ayumu Konno, Hirokazu Hirai, Satoshi Ishido, Takahiro Yoshizawa, Takayuki Shindo, Shingo Takada, Shintaro Kinugawa, Ryoko Inatome, Shigeru Yanagi
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104582- (2022)
Summary: Abnormal mitochondrial fragmentation by dynamin-related protein1 (Drp1) is associated with the progression of aging-associated heart diseases, including heart failure and myocardial infarction (MI). Here, we report a protective role of outer
Externí odkaz:
https://doaj.org/article/eb77f74353bf4977b20163745c270eb9
Autor:
Takumi Kishimoto, Nobukazu Fujimoto, Takeshi Ebara, Toyonori Omori, Tetsuya Oguri, Akio Niimi, Takako Yokoyama, Munehiro Kato, Ikuji Usami, Masayuki Nishio, Kosho Yoshikawa, Takeshi Tokuyama, Mouka Tamura, Yoshifumi Yokoyama, Ken Tsuboi, Yoichi Matsuo, Jiegou Xu, Satoru Takahashi, Mohamed Abdelgied, William T. Alexander, David B. Alexander, Hiroyuki Tsuda
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Malignant pleural mesothelioma (MPM) is a debilitating disease of the pleural cavity. It is primarily associated with previous inhalation of asbestos fibers. These fibers initiate an oxidant coupled inflammatory response. Repeated
Externí odkaz:
https://doaj.org/article/b379711bdc804ece8a34a10fae9cd66a
Publikováno v:
Biology, Vol 10, Iss 10, p 981 (2021)
Mitochondrial cardiomyopathy (MCM) is characterized as an oxidative phosphorylation disorder of the heart. More than 100 genetic variants in nuclear or mitochondrial DNA have been associated with MCM. However, the underlying molecular mechanisms link
Externí odkaz:
https://doaj.org/article/ce482b90afa94cf3a6c88b4ae73a76eb
Autor:
Takeshi Tokuyama, Asei Hirai, Isshin Shiiba, Naoki Ito, Keigo Matsuno, Keisuke Takeda, Kanata Saito, Koki Mii, Nobuko Matsushita, Toshifumi Fukuda, Ryoko Inatome, Shigeru Yanagi
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 450 (2020)
Mitochondria are highly dynamic organelles that constantly fuse, divide, and move, and their function is regulated and maintained by their morphologic changes. Mitochondrial disease (MD) comprises a group of disorders involving mitochondrial dysfunct
Externí odkaz:
https://doaj.org/article/a726f7e98525417a83646675954ee59e
Sarcomere maturation: function acquisition, molecular mechanism, and interplay with other organelles
Publikováno v:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 377(1864)
During postnatal cardiac development, cardiomyocytes mature and turn into adult ones. Hence, all cellular properties, including morphology, structure, physiology and metabolism, are changed. One of the most important aspects is the contractile appara
Publikováno v:
Journal of The Japan Institute of Electronics Packaging. 24:107-114
Autor:
Takeshi Tokuyama, Shigeru Yanagi, Nobuko Matsushita, Shun Nagashima, Naoki Ito, Satoshi Ishido, Toshifumi Fukuda, Ryoko Inatome, Keigo Matsuno, Keito Taniwaka, Keisuke Takeda, Isshin Shiiba
Publikováno v:
The Journal of Biochemistry. 168:305-312
In mitochondrial disorders, short stature and growth failure are common symptoms, but their underlying mechanism remains unknown. In this study, we examined the cause of growth failure of mice induced by nestin promoter-driven knockout of the mitocho
We consider the problem of digitalizing Euclidean segments. Specifically, we look for a constructive method to connect any two points in $$\mathbb {Z}^d$$ Z d . The construction must be consistent (that is, satisfy the natural extension of the Euclid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef45f2ce68156a25e10e5c7c5070e71
Autor:
Nawin Chanthra, Razan E. Ahmed, Tatsuya Anzai, Takeshi Tokuyama, Kumiko A. Iwabuchi, Yutaka Hanazono, Hideki Uosaki
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:182