Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Takeshi Takayanagi"'
Autor:
Shinji Ueno, Yusuke Seino, Shihomi Hidaka, Masashi Nakatani, Keisuke Hitachi, Naoya Murao, Yasuhiro Maeda, Haruki Fujisawa, Megumi Shibata, Takeshi Takayanagi, Katsumi Iizuka, Daisuke Yabe, Yoshihisa Sugimura, Kunihiro Tsuchida, Yoshitaka Hayashi, Atsushi Suzuki
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 9, Pp 1045-1055 (2023)
ABSTRACT Aims/Introduction Glucagon is secreted from pancreatic α‐cells and plays an important role in amino acid metabolism in liver. Various animal models deficient in glucagon action show hyper‐amino acidemia and α‐cell hyperplasia, indica
Externí odkaz:
https://doaj.org/article/f41781e00b1a43f5ac0ed9f6d6341b45
Autor:
Koki Nishida, Shinji Ueno, Yusuke Seino, Shihomi Hidaka, Naoya Murao, Yuki Asano, Haruki Fujisawa, Megumi Shibata, Takeshi Takayanagi, Kento Ohbayashi, Yusaku Iwasaki, Katsumi Iizuka, Shoei Okuda, Mamoru Tanaka, Tadashi Fujii, Takumi Tochio, Daisuke Yabe, Yuuichiro Yamada, Yoshihisa Sugimura, Yoshiki Hirooka, Yoshitaka Hayashi, Atsushi Suzuki
Publikováno v:
Nutrients, Vol 16, Iss 14, p 2270 (2024)
(1) Background: Proglucagon-derived peptides (PDGPs) including glucagon (Gcg), GLP-1, and GLP-2 regulate lipid metabolism in the liver, adipocytes, and intestine. However, the mechanism by which PGDPs participate in alterations in lipid metabolism in
Externí odkaz:
https://doaj.org/article/1ca998ebc1094fd39d80593c666c1578
Autor:
Chika Fujisawa-Tanaka, Izumi Hiratsuka, Megumi Shibata, Kei Kurihara, Naohiro Aida, Takeshi Takayanagi, Yusuke Seino, Taihei Ito, Takashi Kenmochi, Atsushi Suzuki
Publikováno v:
Fujita Medical Journal, Vol 9, Iss 3, Pp 194-199 (2023)
Objectives: Type 1 diabetes mellitus (T1DM) patients with diabetic kidney disease-induced kidney failure have a significantly impaired quality of life (QOL), resulting in a high level of physical, mental, and social anxiety. In this study, we evaluat
Externí odkaz:
https://doaj.org/article/d9c0cb901f6e44cb93ad4e9ee1d32424
Autor:
Shinji Ueno, Yusuke Seino, Shihomi Hidaka, Ryuya Maekawa, Yuko Takano, Michiyo Yamamoto, Mika Hori, Kana Yokota, Atsushi Masuda, Tatsuhito Himeno, Shin Tsunekawa, Hideki Kamiya, Jiro Nakamura, Hitoshi Kuwata, Haruki Fujisawa, Megumi Shibata, Takeshi Takayanagi, Yoshihisa Sugimura, Daisuke Yabe, Yoshitaka Hayashi, Atsushi Suzuki
Publikováno v:
Nutrients, Vol 14, Iss 5, p 975 (2022)
(1) Background: Protein stimulates the secretion of glucagon (GCG), which can affect glucose metabolism. This study aimed to analyze the metabolic effect of a high-protein diet (HPD) in the presence or absence of proglucagon-derived peptides, includi
Externí odkaz:
https://doaj.org/article/550e85e150de4afcbdaf86ee0daed5df
Autor:
Eisuke Tomatsu, Megumi Shibata, Yasumasa Yoshino, Sahoko Sekiguchi-Ueda, Ayako Kakita, Takeshi Takayanagi, Masaki Makino, Nobuki Hayakawa, Atsushi Suzuki
Publikováno v:
Fujita Medical Journal, Vol 4, Iss 1, Pp 1-5 (2018)
Objective: The risk of fracture is higher in people with than without diabetes. Because bone mineral density is not a good predictive marker of bone strength in people with diabetes, another surrogate is needed. Sclerostin is an inhibitor of bone for
Externí odkaz:
https://doaj.org/article/1b45dbb520a041cc8feb9e65497961bf
Autor:
Megumi Shibata, Yoshiaki Ihara, Izumi Hiratsuka, Sahoko Sekiguchi-Ueda, Takeshi Takayanagi, Masaki Makino, Nobuki Hayakawa, Atsushi Suzuki
Publikováno v:
Fujita Medical Journal, Vol 3, Iss 2, Pp 44-47 (2017)
A 34-year-old woman with type 1 diabetes on hemodialysis was admitted to our hospital for simultaneous pancreas kidney transplantation received from her father. She had suffered from type 1 diabetes mellitus since age 13, and had complained of seriou
Externí odkaz:
https://doaj.org/article/38309fd4a5db44b6990e9f46672b5be1
Autor:
Yohei Asada, Takeshi Takayanagi, Tsukasa Kawakami, Eisuke Tomatsu, Atsushi Masuda, Yasumasa Yoshino, Sahoko Sekiguchi-Ueda, Megumi Shibata, Tomihiko Ide, Hajime Niimi, Eishin Yaoita, Yusuke Seino, Yoshihisa Sugimura, Atsushi Suzuki
Publikováno v:
International Journal of Endocrinology, Vol 2019 (2019)
Osteoporosis patients with chronic kidney disease (CKD) are becoming common in our superaging society. Renal dysfunction causes phosphorus accumulation in the circulating plasma and leads to the development of CKD-mineral bone disorder (MBD). We have
Externí odkaz:
https://doaj.org/article/e626e3d2dc784acd9c8a2bfc164e6bca
Autor:
Takeshi Takayanagi, Yoko Kaneko S., Hiroshi Nagasaki, Yu Kodani, Akira Nakashima, Keiji Mori, Atsushi Suzuki, Mitsuyasu Itoh, Kazunao Kondo, Toshiharu Nagatsu, Miyuki Ota, Akira Ota
Publikováno v:
Fujita Medical Journal, Vol 1, Iss 1, Pp 1-5 (2016)
Objectives: According to our previous work, aripiprazole exerted a protective effect on hydrogen peroxide (H2O2)-treated PC12 cells; haloperidol did not. Because aripiprazole has distinct affinities to a set of neurotransmitter receptor subtypes, thi
Externí odkaz:
https://doaj.org/article/eeb57ba85a9d4a5ea3bfd9bbd9855a6a
Autor:
Atsushi Masuda, Yusuke Seino, Masatoshi Murase, Shihomi Hidaka, Megumi Shibata, Takeshi Takayanagi, Yoshihisa Sugimura, Yoshitaka Hayashi, Atsushi Suzuki
Publikováno v:
Nutrients, Vol 11, Iss 5, p 1045 (2019)
Long-term exposure to a high starch, low-protein diet (HSTD) induces body weight gain and hyperinsulinemia concomitantly with an increase in β-cell mass (BCM) and pancreatic islets number in mice; however, the effect of short-term exposure to HSTD o
Externí odkaz:
https://doaj.org/article/5f5ac709a22c46da92513caa4d55dac2
Autor:
Takeshi Takayanagi, Hiroyuki Hirai, Yohei Asada, Takaaki Yamada, Seiji Hasegawa, Eisuke Tomatsu, Yoshiteru Maeda, Yasumasa Yoshino, Izumi Hiratsuka, Sahoko Sekiguchi-Ueda, Megumi Shibata, Yusuke Seino, Yoshihisa Sugimura, Hirohiko Akamatsu, Mitsuyasu Itoh, Atsushi Suzuki
Publikováno v:
Molecular Biology Reports. 49:5875-5882
Aims: Although skin manifestations are common in diabetic patients, its characteristics are poorly identified. This study explored the differentiation process of keratinocytes in type 2 diabetes mellitus (T2DM) in vivo.Methods: Back skin of T2DM mode