Zobrazeno 1 - 10
of 997
pro vyhledávání: '"Takeshi Sakurai"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Most organisms possess three biological oscillators, circadian clock, cell cycle, and redox rhythm, which are autonomous but interact each other. However, whether their interactions and autonomy are beneficial for organisms remains unclear.
Externí odkaz:
https://doaj.org/article/6df2fd3f4c1b48b18bf2c8f047e4334d
Autor:
Ayaka Nakai, Mitsuaki Kashiwagi, Tomoyuki Fujiyama, Kanako Iwasaki, Arisa Hirano, Hiromasa Funato, Masashi Yanagisawa, Takeshi Sakurai, Yu Hayashi
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-9 (2024)
Abstract The AP-2 transcription factors are crucial for regulating sleep in both vertebrate and invertebrate animals. In mice, loss of function of the transcription factor AP-2β (TFAP2B) reduces non-rapid eye movement (NREM) sleep. When and where TF
Externí odkaz:
https://doaj.org/article/15e816988fa64c9093a05a4e7b4ce5c6
Autor:
Akinori Kitsuki, Takeshi Sakurai
Publikováno v:
Agriculture & Food Security, Vol 12, Iss 1, Pp 1-13 (2023)
Abstract Background Seasonality is an important aspect of food security for subsistence households in developing countries. Among the multidimensional aspects of food security, this paper focuses on how unexpected negative harvest shocks would affect
Externí odkaz:
https://doaj.org/article/969dc706c3c24fb8a8d217dc64fdd235
Publikováno v:
Frontiers in Environmental Economics, Vol 3 (2024)
IntroductionIn Ghana and comparable developing countries, advancing farm investments and adopting innovative rice farming techniques encounters obstacles because of climate change. Smallholder farming households, affected by climate events, confront
Externí odkaz:
https://doaj.org/article/0f6b6690b4464b29b79838066a9fc1fc
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Entrainment is characterized by phase response curves (PRCs), which provide a summary of responses to perturbations at each circadian phase. The synchronization of mammalian circadian clocks is accomplished through the receipt of a variety o
Externí odkaz:
https://doaj.org/article/b8b7467d08a0458e861275bd23f1b53e
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Many patients with psychiatric conditions, such as bipolar disorder and major depressive disorder, frequently experience disruptions in their sleep–wake cycles. Several case studies and clinical trials have shown that the administration of aripipra
Externí odkaz:
https://doaj.org/article/c52e6fa4a08a458f876ab63e62267f20
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102321- (2023)
Summary: We present a protocol for inducing a hibernation-like state in free-moving mice using optogenetics. We have recently developed an optogenetic technique utilizing modified Opsin4, which is activated by weak blue light, resulting in prolonged
Externí odkaz:
https://doaj.org/article/e9506a191b334ea88410ae016defa07e
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Video game research predominantly uses a “one game-one function” approach—researchers deploy a constellation of task-like minigames to span multiple domains or consider a complex video game to essentially represent one cognitive constr
Externí odkaz:
https://doaj.org/article/c920b711632b49b08383fde2ea55a3a0
Autor:
Aki Takahashi, Romain Durand-de Cuttoli, Meghan E. Flanigan, Emi Hasegawa, Tomomi Tsunematsu, Hossein Aleyasin, Yoan Cherasse, Ken Miya, Takuya Okada, Kazuko Keino-Masu, Koshiro Mitsui, Long Li, Vishwendra Patel, Robert D. Blitzer, Michael Lazarus, Kenji F. Tanaka, Akihiro Yamanaka, Takeshi Sakurai, Sonoko Ogawa, Scott J. Russo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The dorsal raphe nucleus (DRN) is known to modulate aggressive behaviour in rodents. Here the authors show that glutamatergic projections from the lateral habenula to DRN modulate aggression between male mice.
Externí odkaz:
https://doaj.org/article/d04c343a8d9249c48d96d5f41f361fc1
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Aging disrupts circadian clocks, as evidenced by a reduction in the amplitude of circadian rhythms. Because the circadian clock strongly influences sleep–wake behavior in mammals, age-related alterations in sleep–wake patterns may be attributable
Externí odkaz:
https://doaj.org/article/0b872a620b484d8d89146aa23b9730ac