Zobrazeno 1 - 10
of 367
pro vyhledávání: '"Takeshi SUGAYA"'
Autor:
Hideki Kimura, Kazuko Kamiyama, Toru Imamoto, Izumi Takeda, Mamiko Kobayashi, Naoki Takahashi, Kenji Kasuno, Takeshi Sugaya, Masayuki Iwano
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Cisplatin-induced injury to renal proximal tubular cells stems from mitochondrial damage-induced apoptosis and inflammation. Dichloroacetate (DCA), a pyruvate dehydrogenase kinase (PDK) inhibitor, a potential generator of ROS and ATP, protec
Externí odkaz:
https://doaj.org/article/b817c57363ca4a61a060f910d74cccee
Autor:
Keiichi Tominaga, Mimari Kanazawa, Shoko Watanabe, Takanao Tanaka, Shunsuke Kojimahara, Satoshi Masuyama, Keiichiro Abe, Akira Kanamori, Akira Yamamiya, Takeshi Sugaya, Kenichi Goda, Yuji Fujita, Shigemi Yoshihara, Yasuo Haruyama, Atsushi Irisawa
Publikováno v:
JGH Open, Vol 8, Iss 7, Pp n/a-n/a (2024)
Abstract Background and aim Ulcerative colitis (UC) is characterized by repeated relapse and remission. Because no fundamental therapeutic strategy has been established, the treatment goal is generally to maintain the remission phase for a long perio
Externí odkaz:
https://doaj.org/article/4ea89626ba3d4d879efb76b164d05812
Autor:
Keisei Kosaki, Jiyeon Park, Masahiro Matsui, Takeshi Sugaya, Makoto Kuro-o, Chie Saito, Kunihiro Yamagata, Seiji Maeda
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Inappropriate activation of intrarenal renin–angiotensin system (RAS) may contribute to the pathogenesis of cardio-renal syndrome (CRS). We aimed to examine the cross-sectional associations of urinary angiotensinogen (AGT) excretion, a bio
Externí odkaz:
https://doaj.org/article/940e71416a5a4a7c9d455585b4bd8fb0
Autor:
Hitoshi Kotake, Yuji Ogura, Shohei Yamada, Kazuho Inoue, Shiika Watanabe, Daisuke Ichikawa, Takeshi Sugaya, Keiichi Ohata, Yasunori Natsuki, Seiko Hoshino, Minoru Watanabe, Kenjiro Kimura, Yugo Shibagaki, Atsuko Kamijo-Ikemori
Publikováno v:
Journal of Physiological Sciences, Vol 73, Iss 1, Pp 1-14 (2023)
Abstract We previously reported the significant increase in limb muscle strength and cross-sectional area of the type IIb muscle fibers in the extensor digitorum longus (EDL) muscle in a type 2 diabetic animal model, with Spontaneously Diabetic Torii
Externí odkaz:
https://doaj.org/article/23f1e23b899f41a9b01a07478fb467ce
Autor:
Mariko Kajiwara-Kubota, Kazuhiko Uchiyama, Kohei Asaeda, Reo Kobayashi, Hikaru Hashimoto, Takeshi Yasuda, Satoshi Sugino, Takeshi Sugaya, Yasuko Hirai, Katsura Mizushima, Toshifumi Doi, Ken Inoue, Osamu Dohi, Naohisa Yoshida, Takeshi Ishikawa, Tomohisa Takagi, Hideyuki Konishi, Ryo Inoue, Yoshito Itoh, Yuji Naito
Publikováno v:
npj Science of Food, Vol 7, Iss 1, Pp 1-7 (2023)
Abstract Colonic mucus layers protect intestinal tissues against intestinal bacteria. We investigated the effects of dietary fiber and its metabolites on mucus production in the colonic mucosa. Mice were fed a partially hydrolyzed guar gum (PHGG)-con
Externí odkaz:
https://doaj.org/article/ace04763e0f64302b9dbde9079fdcfa6
Autor:
Suguru Takayama, Kazuho Inoue, Yuji Ogura, Seiko Hoshino, Takeshi Sugaya, Keiichi Ohata, Hitoshi Kotake, Daisuke Ichikawa, Minoru Watanabe, Kenjiro Kimura, Yugo Shibagaki, Atsuko Kamijo-Ikemori
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract The study aim was to determine if suppressed activation of angiotensin II type 1 receptor (AT1) prevents severe muscle atrophy after denervation. The sciatic nerves in right and left inferior limbs were cut in AT1a knockout homo (AT1a−/−
Externí odkaz:
https://doaj.org/article/302eda8b533b4257b9fde85f7359276c
Autor:
Satoshi Takashima, Tomomi Nasu, Keiichi Ohata, Tsuyoshi Oikawa, Takeshi Sugaya, Yui Kobatake, Sanae Shibata, Naohito Nishii
Publikováno v:
Open Veterinary Journal, Vol 12, Iss 6, Pp 864-867 (2022)
Background: Fanconi syndrome (FS) is defined as multiple defects of the proximal tubules and is diagnosed by clinical symptoms. However, in dogs with FS, the damage in the proximal tubules that are responsible for the clinical symptoms has not been e
Externí odkaz:
https://doaj.org/article/049a1ad232484b6a8ee12325879ed9eb
Autor:
Natsumi Nishitani, Keisei Kosaki, Shoya Mori, Masahiro Matsui, Takeshi Sugaya, Makoto Kuro-o, Chie Saito, Kunihiro Yamagata, Seiji Maeda
Publikováno v:
Geriatrics, Vol 8, Iss 6, p 118 (2023)
Age-related loss of lower extremity muscle strength is pronounced in individuals with chronic kidney disease (CKD). In contrast, an increase in intrarenal flow pulsatility results in initial age-related changes in renal hemodynamics, leading to the d
Externí odkaz:
https://doaj.org/article/20244606f3d846f8bfeff949b9df4e78
Autor:
Yuka Suzuki, Koki Hoshi, Keiichi Tominaga, Yasunori Inaba, Tomonori Yoshinaga, Shunsuke Kojimahara, Ryuichi Maki, Rena Nemoto, Yugo Tetsuka, Yosuke Kawata, Akira Yamamiya, Takeshi Sugaya, Yukihiro Iso, Atsuko Takada‐Owada, Kazuyuki Ishida, Kenichi Goda, Atsushi Irisawa
Publikováno v:
DEN Open, Vol 3, Iss 1, Pp n/a-n/a (2023)
Abstract A 38‐year‐old woman was admitted to our hospital for a detailed examination of jaundice. Three years before, she had undergone a right total mastectomy and axillary lymph node dissection of her right breast because of cancer. Histopathol
Externí odkaz:
https://doaj.org/article/dc33c2e5b4204caba6013b702d62ebcf
Urinary L-Type Fatty Acid-Binding Protein Predicts Oxygen Demand of COVID-19 in Initially Mild Cases
Autor:
Daisuke Katagiri, MD, PhD, FASN, Yusuke Asai, PhD, Norio Ohmagari, MD, PhD, Masahiro Ishikane, MD, PhD, Sayaka Hikida, MD, PhD, Noriko Iwamoto, MD, PhD, Maki Nagashima, MT, Minami Suzuki, MD, PhD, Hideki Takano, MD, PhD, Jin Takasaki, MD, Masayuki Hojo, MD, PhD, Haruhito Sugiyama, MD, PhD, Katsushi Tokunaga, PhD, Yoshihiro Miyashita, MD, Masao Omata, MD, PhD, Keiichi Ohata, MS, Kevin P. Bliden, MBA, Udaya S. Tantry, PhD, Jeffrey R. Dahlen, PhD, Takeshi Sugaya, PhD, Paul A. Gurbel, MD, FACC, Eisei Noiri, MD, PhD, FASN
Publikováno v:
Critical Care Explorations, Vol 5, Iss 3, p e0873 (2023)
IMPORTANCE:. Early detection of illness trajectory in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients is crucial for patients and healthcare workers. An effective, noninvasive approach, with simple measurement for decis
Externí odkaz:
https://doaj.org/article/c441b337caae44d7ad8b8954bdd690ac