Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Takeshi Nara"'
Autor:
Matus Valach, Sandrine Moreira, Celine Petitjean, Corinna Benz, Anzhelika Butenko, Olga Flegontova, Anna Nenarokova, Galina Prokopchuk, Tom Batstone, Pascal Lapébie, Lionnel Lemogo, Matt Sarrasin, Paul Stretenowich, Pragya Tripathi, Euki Yazaki, Takeshi Nara, Bernard Henrissat, B. Franz Lang, Michael W. Gray, Tom A. Williams, Julius Lukeš, Gertraud Burger
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Diplonemid flagellates are among the most abundant and species-rich of known marine microeukaryotes, colonizing all habitats, depths, and geographic regions of the world ocean. However, little is known about their genomes, biology
Externí odkaz:
https://doaj.org/article/d52b66df69fd49b39786a1f81803704a
Autor:
Yuki Tayama, Shusaku Mizukami, Kazufumi Toume, Katsuko Komatsu, Tetsuo Yanagi, Takeshi Nara, Paul Tieu, Nguyen Tien Huy, Shinjiro Hamano, Kenji Hirayama
Publikováno v:
Tropical Medicine and Health, Vol 51, Iss 1, Pp 1-12 (2023)
Abstract Background Current therapeutic agents, including nifurtimox and benznidazole, are not sufficiently effective in the chronic phase of Trypanosoma cruzi infection and are accompanied by various side effects. In this study, 120 kinds of extract
Externí odkaz:
https://doaj.org/article/370c70bf44ab45399f76ef65c49a72ab
Autor:
Fariz Nurwidya, Fumiyuki Takahashi, Wira Winardi, Ken Tajima, Yoichiro Mitsuishi, Akiko Murakami, Isao Kobayashi, Takeshi Nara, Muneaki Hashimoto, Motoyasu Kato, Moulid Hidayat, Kentaro Suina, Daisuke Hayakawa, Tetsuhiko Asao, Ryo Ko, Takehito Shukuya, Toshifumi Yae, Naoko Shimada, Yasuko Yoshioka, Shinichi Sasaki, Kazuhisa Takahashi
Publikováno v:
Thoracic Cancer, Vol 12, Iss 10, Pp 1536-1548 (2021)
Abstract Background Zinc‐finger E‐box‐binding homeobox 1 (ZEB1) is an important regulator of epithelial‐mesenchymal transition (EMT) and is involved in the maintenance of cancer stem cells (CSCs) via miR‐200c and BMI1 pathway. Recent studie
Externí odkaz:
https://doaj.org/article/e0c295a0b0984d87948db725cae9d493
Autor:
Muneaki Hashimoto, Motomichi Doi, Nagomi Kurebayashi, Koji Furukawa, Hiroko Hirawake‐Mogi, Yoshihiro Ohmiya, Takashi Sakurai, Toshihiro Mita, Katsuhiko Mikoshiba, Takeshi Nara
Publikováno v:
FEBS Open Bio, Vol 6, Iss 12, Pp 1178-1185 (2016)
Regulation of intracellular Ca2+ concentration ([Ca2+]i) is vital for eukaryotic organisms. Recently, we identified a Ca2+ channel (TcIP3R) associated with intracellular Ca2+ stores in Trypanosoma cruzi, the parasitic protist that causes Chagas disea
Externí odkaz:
https://doaj.org/article/de8994074b064fe78e98f4c51fd4e836
Autor:
Daniel Ken Inaoka, Maiko Iida, Toshiyuki Tabuchi, Teruki Honma, Nayoung Lee, Satoshi Hashimoto, Shigeru Matsuoka, Takefumi Kuranaga, Kazuhito Sato, Tomoo Shiba, Kimitoshi Sakamoto, Emmanuel Oluwadare Balogun, Shigeo Suzuki, Takeshi Nara, Josmar Rodrigues da Rocha, Carlos Alberto Montanari, Akiko Tanaka, Masayuki Inoue, Kiyoshi Kita, Shigeharu Harada
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167078 (2016)
Many open form (OF) structures of drug targets were obtained a posteriori by analysis of co-crystals with inhibitors. Therefore, obtaining the OF structure of a drug target a priori will accelerate development of potent inhibitors. In addition to its
Externí odkaz:
https://doaj.org/article/3a23ea416020435288da3735a0f01c84
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135726 (2015)
Trypanosoma cruzi is a parasitic protist that causes Chagas disease, which is prevalent in Latin America. Because of the unavailability of an effective drug or vaccine, and because about 8 million people are infected with the parasite worldwide, the
Externí odkaz:
https://doaj.org/article/fe4bf65811534aa6bfff593fa2139d26
Autor:
Tu-Bin Chu, Chien-Wei Liao, Takeshi Nara, Ying-Chie Huang, Chia-Mei Chou, Yu-Hsin Liu, Chia-Kwung Fan
Publikováno v:
Revista da Sociedade Brasileira de Medicina Tropical, Vol 45, Iss 5, Pp 646-648 (2012)
INTRODUCTION: Whether Enterobius vermicularis (pinworm) infections among preschool children in Taipei City had truly declined was investigated. METHODS: A total of 6,661 preschool children from 28 nurseries were randomly selected from 4 major geograp
Externí odkaz:
https://doaj.org/article/2a1c95b3c571493f8bf2def5ed334c5f
Autor:
Akiko Murakami, Fumiyuki Takahashi, Fariz Nurwidya, Isao Kobayashi, Kunihiko Minakata, Muneaki Hashimoto, Takeshi Nara, Motoyasu Kato, Ken Tajima, Naoko Shimada, Shin-ichiro Iwakami, Mariko Moriyama, Hiroyuki Moriyama, Fumiaki Koizumi, Kazuhisa Takahashi
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86459 (2014)
Accumulating evidence indicates that a small population of cancer stem cells (CSCs) is involved in intrinsic resistance to cancer treatment. The hypoxic microenvironment is an important stem cell niche that promotes the persistence of CSCs in tumors.
Externí odkaz:
https://doaj.org/article/6fe64e8a410a4a28a601b63bfd11afbb
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37183 (2012)
BACKGROUND: The flagellate protozoan parasite, Trypanosoma cruzi, is a causative agent of Chagas disease that is transmitted by reduviid bugs to humans. The parasite exists in multiple morphological forms in both vector and host, and cell differentia
Externí odkaz:
https://doaj.org/article/e3b91397e1d54fc580c8c93e54bec7ac
Autor:
Ryo Ko, Ken Tajima, Isao Kobayashi, Toshifumi Yae, Muneaki Hashimoto, Yasuko Yoshioka, Yoichiro Mitsuishi, Naoko Shimada, Fariz Nurwidya, Fumiyuki Takahashi, Wira Winardi, Shinichi Sasaki, Takeshi Nara, Daisuke Hayakawa, Kentaro Suina, Akiko Murakami, Moulid Hidayat, Kazuhisa Takahashi, Motoyasu Kato, Takehito Shukuya, Tetsuhiko Asao
Publikováno v:
Thoracic Cancer, Vol 12, Iss 10, Pp 1536-1548 (2021)
Thoracic Cancer
Thoracic Cancer
Background Zinc‐finger E‐box‐binding homeobox 1 (ZEB1) is an important regulator of epithelial‐mesenchymal transition (EMT) and is involved in the maintenance of cancer stem cells (CSCs) via miR‐200c and BMI1 pathway. Recent studies reveale