Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Takeshi MURAKAWA"'
Autor:
Takeshi Murakawa, Kazuo Kurihara, Motoyasu Adachi, Katsuhiro Kusaka, Katsuyuki Tanizawa, Toshihide Okajima
Publikováno v:
IUCrJ, Vol 9, Iss 3, Pp 342-348 (2022)
Protein neutron crystallography is a powerful technique to determine the positions of H atoms, providing crucial biochemical information such as the protonation states of catalytic groups and the geometry of hydrogen bonds. Recently, the crystal stru
Externí odkaz:
https://doaj.org/article/1a3bcf7b297c49efaa0359172fcaa394
Autor:
Youichi Suzuki, Takeshi Murakawa
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12619 (2022)
Flaviviruses (the genus Flavivirus of the Flaviviridae family) include many arthropod-borne viruses, often causing life-threatening diseases in humans, such as hemorrhaging and encephalitis. Although the flaviviruses have a significant clinical impac
Externí odkaz:
https://doaj.org/article/8481cc7d693c407aa04c6f03315bbaa1
Autor:
Seiki BABA, Takeshi MURAKAWA
Publikováno v:
Nihon Kessho Gakkaishi. 64:285-289
Autor:
Yasuo Watanabe, Youichi Suzuki, Akino Emi, Takeshi Murakawa, Takayuki Hishiki, Fumihiro Kato, Shoichi Sakaguchi, Hong Wu, Takato Yano, Chang-Kweng Lim, Tomohiko Takasaki, Takashi Nakano
Publikováno v:
Biochemical and Biophysical Research Communications. 637:181-188
The Chikungunya virus (CHIKV), an enveloped RNA virus that has been identified in over 40 countries and is considered a growing threat to public health worldwide. However, there is no preventive vaccine or specific therapeutic drug for CHIKV infectio
Publikováno v:
Life Science Alliance; Oct2023, Vol. 6 Issue 10, p1-11, 11p
Autor:
Mitsuo Shoji, Takeshi Murakawa, Shota Nakanishi, Mauro Boero, Yasuteru Shigeta, Hideyuki Hayashi, Toshihide Okajima
Publikováno v:
Chemical Science
Chemical Science, 2022, 13 (36), pp.10923-10938. ⟨10.1039/D2SC01356H⟩
Chemical Science, 2022, 13 (36), pp.10923-10938. ⟨10.1039/D2SC01356H⟩
International audience; Copper amine oxidase from Arthrobacter globiformis (AGAO) catalyses the oxidative deamination of primary amines via a large conformational change of a topaquinone (TPQ) cofactor during the semiquinone formation step. This conf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281de9fa6dd4fc2b498674cf01e27ac0
https://hal.science/hal-03782770/document
https://hal.science/hal-03782770/document
Autor:
Takeshi Murakawa, Mamoru Suzuki, Kenji Fukui, Tetsuya Masuda, Michihiro Sugahara, Kensuke Tono, Tomoyuki Tanaka, So Iwata, Eriko Nango, Takato Yano, Katsuyuki Tanizawa, Toshihide Okajima
Publikováno v:
Acta crystallographica. Section D, Structural biology. 78(Pt 12)
The mechanisms by which enzymes promote catalytic reactions efficiently through their structural changes remain to be fully elucidated. Recent progress in serial femtosecond X-ray crystallography (SFX) using X-ray free-electron lasers (XFELs) has mad
Autor:
Tomoko Sunami, Motoyasu Adachi, Ryota Kuroki, Taro Tamada, Toshihide Okajima, Taro Yamada, Yasuteru Shigeta, Takato Yano, Mitsuo Shoji, Katsuhiro Kusaka, Hideyuki Hayashi, Katsuyuki Tanizawa, Chie Shibazaki, Mamoru Suzuki, Naomine Yano, Takeshi Murakawa, Kazuo Kurihara
Publikováno v:
Proc Natl Acad Sci U S A
Recent advances in neutron crystallographic studies have provided structural bases for quantum behaviors of protons observed in enzymatic reactions. Thus, we resolved the neutron crystal structure of a bacterial copper (Cu) amine oxidase (CAO), which
Publikováno v:
Structure (London, England : 1993). 30(7)
MutS family proteins are classified into MutS-I and -II lineages: MutS-I recognizes mismatched DNA and initiates mismatch repair, whereas MutS-II recognizes DNA junctions to modulate recombination. MutS-I forms dimeric clamp-like structures enclosing
Autor:
Maya Nakatani, Shun-ya Nakahara, Kenji Fukui, Momoka Urano, Yuki Fujii, Takeshi Murakawa, Seiki Baba, Takashi Kumasaka, Hiroki Okanishi, Yoshikatsu Kanai, Takato Yano, Ryoji Masui
Publikováno v:
Journal of Structural Biology. 214:107904
Fatty acid kinase is necessary for the incorporation of exogenous fatty acids into membrane phospholipids. Fatty acid kinase consists of two components: a kinase component, FakA, that phosphorylates a fatty acid bound to a fatty acid-binding componen