Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Takeshi Katafuchi"'
Autor:
Takeshi Katafuchi, Makoto Makishima
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6046 (2022)
Bile acids (BAs) are a group of amphiphilic molecules consisting of a rigid steroid core attached to a hydroxyl group with a varying number, position, and orientation, and a hydrophilic side chain. While BAs act as detergents to solubilize lipophilic
Externí odkaz:
https://doaj.org/article/cab38bf128eb43f9a6229843be0d4c58
Autor:
Yuan Zhang, Yang Xie, Eric D Berglund, Katie Colbert Coate, Tian Teng He, Takeshi Katafuchi, Guanghua Xiao, Matthew J Potthoff, Wei Wei, Yihong Wan, Ruth T Yu, Ronald M Evans, Steven A Kliewer, David J Mangelsdorf
Publikováno v:
eLife, Vol 1 (2012)
Fibroblast growth factor-21 (FGF21) is a hormone secreted by the liver during fasting that elicits diverse aspects of the adaptive starvation response. Among its effects, FGF21 induces hepatic fatty acid oxidation and ketogenesis, increases insulin s
Externí odkaz:
https://doaj.org/article/4b4ce4845cdd40c5b506669b2962b9ef
Autor:
Takeshi Katafuchi, Makoto Makishima
Publikováno v:
Journal of Nihon University Medical Association. 80:15-19
Autor:
Ulrich Beuers, Takeshi Katafuchi, Davor Slijepcevic, Reinout L.P. Roscam Abbing, Joanne M. Donkers, Jonathan H. M. van der Meer, Alfred H. Schinkel, Stéphanie van Hoppe, Ronald P.J. Oude Elferink, Manon E. Wildenberg, Stan F.J. van de Graaf, Dagmar Tolenaars, Antje Blank, Dirk R. de Waart
Publikováno v:
Hepatology (Baltimore, Md.)
Hepatology (Baltimore, Md.), 66(5), 1631-1643. John Wiley and Sons Ltd
Hepatology (Baltimore, Md.), 66(5), 1631-1643. John Wiley and Sons Ltd
The Na+ -taurocholate cotransporting polypeptide (NTCP/SLC10A1) is believed to be pivotal for hepatic uptake of conjugated bile acids. However, plasma bile acid levels are normal in a subset of NTCP knockout mice and in mice treated with myrcludex B,
Autor:
Rahul K. Kollipara, Steven A. Kliewer, Ralf Kittler, David J. Mangelsdorf, Takeshi Katafuchi, William L. Holland
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Covalent attachment of small ubiquitin-related modifier (SUMOylation) is a posttranslational modification that regulates the activity of many transcription factors. The nuclear receptor peroxisome proliferator-activated receptor gamma (P
Autor:
Xunshan Ding, Takeshi Katafuchi, Andrew Lemoff, Hamid Mirzaei, Varun Sondhi, Daria Esterházy, Steven A. Kliewer, David J. Mangelsdorf
Publikováno v:
Cell metabolism
SummaryFibroblast growth factor 15 (FGF15) has been proposed as a postprandial hormone that signals from intestine to liver to regulate bile acid and carbohydrate homeostasis. However, detecting FGF15 in blood using conventional techniques has proven
Publikováno v:
Peptides. 31:1906-1911
Adipogenesis is regulated by a wide variety of compounds. An adipogenic cocktail containing insulin (INS), dexamethasone (DEX) and 3-isobutyl-1-methyl xanthine (IBMX) is routinely used to induce adipogenesis in 3T3-L1 preadipocytes, but the biochemic
Publikováno v:
Peptides. 30:1753-1762
This review focuses on the evolutionary and functional relationship of calcitonin receptor-stimulating peptide (CRSP) with calcitonin (CT)/calcitonin gene-related peptide (CGRP) in mammals. CRSP shows high sequence identity with CGRP, but distinct bi
Publikováno v:
Journal of Endocrinology. 198:429-437
We have recently reported the isolation of three new members of the calcitonin (CT) gene-related peptide family of peptides, the CT receptor (CT-R)-stimulating peptides (CRSPs). We now report the sequencing and characterization of ovine/caprine CRSP-
Autor:
Noriko Hiraiwa, Abdol Hossein Rezaeian, Midori Yoshizawa, T. Saito, Kazumasa Hamano, Takeshi Katafuchi, Masahide Nishibori, Naoto Minamino, H. Yasue
Publikováno v:
Cytogenetic and Genome Research. 121:41-49
Recently we identified and characterized porcine calcitonin receptor-stimulating peptide (CRSP) 1, CRSP2 and CRSP3 as members of the calcitonin/calcitonin gene-related peptide (CT/CGRP) family. In the present study, the genomic sequences and organiza