Zobrazeno 1 - 10
of 341
pro vyhledávání: '"Takeshi Izawa"'
Publikováno v:
Open Veterinary Journal, Vol 13, Iss 6, Pp 742-752 (2023)
Background: Hypertrophic cardiomyopathy (HCM) is considered rare in dogs, and there is a lack of clinical data. Cardiac troponin I (cTnI) is a biomarker of cardiomyocyte damage and necrosis and can be used to diagnose cat and human HCM. Aim: We inves
Externí odkaz:
https://doaj.org/article/996e5a2834274f8f94cb7c422aeb05c7
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Moso bamboo (Phyllostachys edulis) is a typical East Asian bamboo that does not flower for > 60 years and propagates without seed reproduction. Thus, Moso bamboo can be propagated vegetatively, possibly resulting in highly heteroz
Externí odkaz:
https://doaj.org/article/c54f108504204718a53c0da8533a04ab
Autor:
Jinying Cui, Noriko Nishide, Kiyoshi Mashiguchi, Kana Kuroha, Masayuki Miya, Kazuhiko Sugimoto, Jun-Ichi Itoh, Shinjiro Yamaguchi, Takeshi Izawa
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Fertilization controls various aspects of cereal growth such as tiller number, leaf size, and panicle size. However, despite such benefits, global chemical fertilizer use must be reduced to achieve sustainable agriculture. Here, based on fie
Externí odkaz:
https://doaj.org/article/012c7f41b9f44ca680ef1f12827a2407
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Hepatic iron overload is often concurrent with nonalcoholic fatty liver disease (NAFLD). Dysmetabolic iron overload syndrome (DIOS) is characterized by an increase in the liver and body iron stores and metabolic syndrome components. Increasi
Externí odkaz:
https://doaj.org/article/eaf9eaa5909e45a2aa1f20f0d8133e84
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Mutations in the cell proliferation regulator K-Ras are found with a variety of cancer types, so drugs targeting these mutant proteins could hold great clinical potential. Very recently, a drug targeting the K-Ras(G12C) mutant observed in lu
Externí odkaz:
https://doaj.org/article/56478475c00642258083c3d1b2b3db27
Autor:
Naoshige Ono, Takashi Fujita, Mariko Miki, Kazuhiro Nishiyama, Takeshi Izawa, Tomoko Aoyama, Mitsuru Kuwamura, Hideki Fujii, Yasu-Taka Azuma
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 2064 (2023)
IL-19 is a cytokine discovered by homologous searching with IL-10 and is produced by non-immune cells, such as keratinocytes, in addition to immune cells, such as macrophages. Liver fibrosis results from the inflammation and activation of hepatic ste
Externí odkaz:
https://doaj.org/article/0762a9cd455949bd85adecfa121e2d8f
Autor:
Hayato Yoshioka, Keiko Kimura, Yuko Ogo, Namie Ohtsuki, Ayako Nishizawa-Yokoi, Hironori Itoh, Seiichi Toki, Takeshi Izawa
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Flowering is an important biological process through which plants determine the timing of reproduction. In rice, florigen mRNA is induced more strongly when the day length is shorter than the critical day length through recognition of 30-min differen
Externí odkaz:
https://doaj.org/article/12cdc3abd6104fcd8dd75a3b62304255
Autor:
Daluthgamage Patsy Himali Wijesekera, Eiji Yuba, Nadeeka Harshini De Silva, Shun‐ichi Watanabe, Masaya Tsukamoto, Chihiro Ichida, Takeshi Izawa, Kazuyuki Itoh, Ryoji Kanegi, Shingo Hatoya, Jyoji Yamate, Toshio Inaba, Kikuya Sugiura
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 1, Pp 5-17 (2020)
Abstract The tumor microenvironment strongly influences clinical outcomes of immunotherapy. By transfecting genes of relevant cytokines into tumor cells, we sought to manipulate the microenvironment so as to elicit activation of T helper type 1 (Th1)
Externí odkaz:
https://doaj.org/article/f401c6ebf60e42a7b26d020a66ede3de
Autor:
Naoki Harada, Yukari Minami, Kazuki Hanada, Ryo Hanaoka, Yasuyuki Kobayashi, Takeshi Izawa, Takashi Sato, Shigeaki Kato, Hiroshi Inui, Ryoichi Yamaji
Publikováno v:
Gut Microbes, Vol 12, Iss 1 (2020)
Androgen action generates sex-related differences that include changes in the gut microbiota composition. Hypoandrogenism and hyperandrogenism in males and females, respectively, are associated with the prevalence of metabolic disorders. Our recent w
Externí odkaz:
https://doaj.org/article/a5c9440d90c84487acbf93ebf6b4b7ba
Autor:
Yasu-Taka Azuma, Takashi Fujita, Takeshi Izawa, Kana Hirota, Kazuhiro Nishiyama, Airi Ikegami, Tomoko Aoyama, Mikihito Ike, Yumi Ushikai, Mitsuru Kuwamura, Hideki Fujii, Koichi Tsuneyama
Publikováno v:
Cells, Vol 10, Iss 12, p 3513 (2021)
Interleukin (IL)-19, a member of the IL-10 family, is an anti-inflammatory cytokine produced primarily by macrophages. Nonalcoholic steatohepatitis (NASH) is a disease that has progressed from nonalcoholic fatty liver disease (NAFLD) and is character
Externí odkaz:
https://doaj.org/article/473f955a8b6547389d1442ab0e570335