Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Takeshi Inde"'
Publikováno v:
Organic & Biomolecular Chemistry. 17:859-866
To systematically determine the effect of N2-heteroaryl modification on the stability of G-quadruplex structures, six types of N2-heteroarylated deoxyguanosines were incorporated into oligonucleotides with intramolecular quadruplex-forming sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::637b6b2a989aedd0f36a4c9fde56adb5
https://doi.org/10.1039/c8ob03100b
https://doi.org/10.1039/c8ob03100b
Autor:
Jun Tanihata, Keishi Yamamoto, Kohji Seio, Shin'ichi Takeda, Tetsuya Nagata, Keita Yoshida, Atsuya Maruyama, Takeshi Inde, Yoshiaki Masaki, Mitsuo Sekine
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:160-163
The effect of 2'-O-(N-methylcarbamoyl)ethyl (MCE) modification on splice-switching oligonucleotides (SSO) was systematically evaluated. The incorporation of five MCE nucleotides at the 5'-termini of SSOs effectively improved the splice switching effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c963e4f11018ff85a1e966b5aaeb58e
https://doi.org/10.1016/j.bmcl.2018.12.005
https://doi.org/10.1016/j.bmcl.2018.12.005
Autor:
Shuhei Nishizawa, Takashi Kanamori, Takeshi Inde, Akihiro Ohkubo, Kohji Seio, Yuusaku Hattori, Hideya Yuasa, Mitsuo Sekine
Publikováno v:
Bioorganic & Medicinal Chemistry. 26(No. 13):3785-3790
This study aimed to synthesize triplex-forming oligonucleotides (TFOs) containing 2'-deoxy-6-thioxanthosine (s6X) and 2'-deoxy-6-thioguanosine (s6Gs) residues and examined their triplex-forming ability. Consecutive arrangement of s6X and s6Gs residue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ad8214b1ca3b156cbf28c420c9d46f
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100786561
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100786561
Autor:
Kohji Seio, Mitsuo Sekine, Yoshiaki Masaki, Yuya Miyatake, Takahito Tomori, Yu Ito, Naoaki Makio, Takeshi Inde, Atsuya Maruyama
Publikováno v:
Organic & Biomolecular Chemistry. 15:8371-8383
To systematically understand the effect of 2-N-heteroarylguanine (GHA) modification on the stability of higher-order DNA structures, nucleoside derivatives and oligodeoxyribonucleotides containing guanine residues modified with four kinds of hereroar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506673ef8f563bfdbe20026cc2c19b92
https://doi.org/10.1039/c7ob01875d
https://doi.org/10.1039/c7ob01875d
Publikováno v:
Organicbiomolecular chemistry. 17(4)
To systematically determine the effect of N2-heteroaryl modification on the stability of G-quadruplex structures, six types of N2-heteroarylated deoxyguanosines were incorporated into oligonucleotides with intramolecular quadruplex-forming sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ef5ca81cb63d22fc22dbfd9654e057d
https://pubmed.ncbi.nlm.nih.gov/30627713
https://pubmed.ncbi.nlm.nih.gov/30627713
Autor:
Shin'ichi Takeda, Tetsuya Nagata, Mitsuo Sekine, Takashi Kanamori, Yoshiaki Masaki, Takeshi Inde, Jun Tanihata, Kohji Seio
Publikováno v:
Med. Chem. Commun.. 6:630-633
Incorporation of 2′-O-methyl-2-thioribothymidine (s2Tm) into antisense oligoribonucleotides significantly enhanced the exon skipping activity in Duchenne muscular dystrophy model mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfe83afc06759685facafc3788e53b2
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100724912
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100724912
Autor:
Kohji Seio, Yusaku Hattori, Akihiro Ohkubo, Mitsuo Sekine, Kenji Yamada, Takashi Kanamori, Takeshi Inde
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(3)
The consecutive arrangement of 2'-deoxy-6-thioguanosines (s(6)Gs) and 4-thiothymidines (s(4)Ts) in antiparallel triplex-forming oligonucleotides (TFOs) considerably stabilized the resulting antiparallel triplexes with high base recognition ability by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23888a006ffd88f0444f44ed3c810ea9
https://pubmed.ncbi.nlm.nih.gov/23287737
https://pubmed.ncbi.nlm.nih.gov/23287737