Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Takeshi Ikeya"'
Publikováno v:
Cell Transplantation, Vol 18 (2009)
Three-dimensional culture procedures have attracted attention in various fields of cell biology. A newly developed cell array assisted in the formation of hepatocyte spheroids by two innovations: 1) micropatterning by a hydrophilic polymer, and 2) th
Externí odkaz:
https://doaj.org/article/a75e9d7834ab48b2bb304bdcbb2fa939
Autor:
Yoshitaka Miyamoto, Yumie Koshidaka, Katsutoshi Murase, Shoichiro Kanno, Hirofumi Noguchi, Kenji Miyado, Takeshi Ikeya, Satoshi Suzuki, Tohru Yagi, Naozumi Teramoto, Shuji Hayashi
Publikováno v:
Materials; Volume 15; Issue 21; Pages: 7823
Establishing a rapid in vitro evaluation system for drug screening is essential for the development of new drugs. To reproduce tissues/organs with functions closer to living organisms, in vitro three-dimensional (3D) culture evaluation using microfab
Publikováno v:
European Cells & Materials, Vol 12, Pp 36-43 (2006)
This study demonstrates that boronic acid-containing polymers coated onto solid support function as synthetic mitogens for mouse lymphocytes. The polymer was synthesized by radical copolymerization of 3-acrylamidophenylboronic acid with dimethylacryl
Autor:
Tadayoshi Ueda, Hisakazu Iwai, Takeshi Ikeya, Takuo Ogihara, Takuya Nagao, Naoki Takahashi, Yukiko Inoue, Hiroshi Arakawa, Kumiko Kusumoto, Kazushi Naitoh, Emiko Ozeki, Kunihiro Ohta, Takako Ohkura, Kazuki Wada, Akiko Koeda, Tomoko Jomura
Publikováno v:
Drug metabolism and pharmacokinetics. 29(5)
We investigated the utility of three-dimensional (3D) spheroid cultures of human hepatocytes in discovering drug metabolites. Metabolites of acetaminophen, diclofenac, lamotrigine, midazolam, propranolol and salbutamol were analyzed by liquid chromat
Publikováno v:
Reactive and Functional Polymers. 37:251-261
Interaction of rat lymphocyte subpopulations (B cells and T cells) with surfaces of poly ( N,N -dimethylacryl-amide- co -3-acrylamidophenylboronic acid) (DB copolymers) with varying composition was evaluated under a controlled shear stress by using a
Autor:
Hisashi Iwata, Yoshitaka Miyamoto, Yoshinobu Baba, Yumie Koshidaka, Hirofumi Noguchi, Takeshi Ikeya, Shuji Hayashi, Satoshi Suzuki, Hiroaki Saito, Koichi Oishi, Hiroshi Yukawa, Katsutoshi Murase, Noritada Kaji
Magnetic resonance imaging (MRI) using magnetic nanoparticles has been used to diagnose vascular diseases as well as to monitor transplanted cells and tissues. In this study, we synthesized magnetic iron oxide nanoparticles (TMADM-03), electrically c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa777ec480ad41c21576127e458fcb8
https://europepmc.org/articles/PMC4733861/
https://europepmc.org/articles/PMC4733861/
One major purpose of cell culture is the reconstruction of physiological structures. Using bovine aortic epithelium cell line HH (JCRB0099) as feeder cells and rat primary hepatocytes, we constructed hepatic lobule-like spheroids on a cell array plat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d667c80ee20d9423665627aadb59b38a
https://europepmc.org/articles/PMC5196923/
https://europepmc.org/articles/PMC5196923/
Autor:
Hirofumi Noguchi, Katsutoshi Murase, Hiroaki Saito, Noritada Kaji, Hiroshi Yukawa, V. Y. Koshidaka, Takeshi Ikeya, Shuji Hayashi, Yoshinobu Baba, Yoshitaka Miyamoto, Hisashi Iwata, Koichi Oishi
Publikováno v:
ACS Symposium Series ISBN: 9780841227187
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77926de335b1cdfd715507a7d00e8563
https://doi.org/10.1021/bk-2012-1119.ch009
https://doi.org/10.1021/bk-2012-1119.ch009
Publikováno v:
Cell Transplantation, Vol 18 (2009)
Three-dimensional culture procedures have attracted attention in various fields of cell biology. A newly developed cell array assisted in the formation of hepatocyte spheroids by two innovations: 1) micropatterning by a hydrophilic polymer, and 2) th
Publikováno v:
Cancer Research. 73:3838-3838
Recently, the cell biology field has come to appreciate the dissimilarity between two- (2D) and three-dimensional (3D) environments in which cells routinely operate in vivo. Efficacy of most anti-cancer drugs have been evaluated in 2D environment but