Zobrazeno 1 - 10
of 328
pro vyhledávání: '"Takeshi HORI"'
Autor:
Tomoko Kodama, Takashi Imajima, Mototsugu Shimokawa, Taiga Otsuka, Masahiro Kawahira, Junichi Nakazawa, Takeshi Hori, Taro Shibuki, Shiho Arima, Akio Ido, Keisuke Miwa, Yoshinobu Okabe, Futa Koga, Yujiro Ueda, Yoshihito Kubotsu, Hozumi Shimokawa, Shigeyuki Takeshita, Kazuo Nishikawa, Azusa Komori, Satoshi Otsu, Ayumu Hosokawa, Tatsunori Sakai, Kenji Sakai, Hisanobu Oda, Machiko Kawahira, Shuji Arita, Takuya Honda, Hiroki Taguchi, Kengo Tsuneyoshi, Yasunori Kawaguchi, Toshihiro Fujita, Takahiro Sakae, Tsuyoshi Shirakawa, Toshihiko Mizuta, Kenji Mitsugi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Nanoliposomal irinotecan with fluorouracil and folinic acid (NFF) is a standard regimen after gemcitabine-based therapy for patients with unresectable or recurrent pancreatic cancer. However, there are limited clinical data on its efficacy a
Externí odkaz:
https://doaj.org/article/eebc9af936314345b048057f5416b5fd
Autor:
Takeshi Hori, Hiroaki Okae, Shun Shibata, Norio Kobayashi, Eri H. Kobayashi, Akira Oike, Asato Sekiya, Takahiro Arima, Hirokazu Kaji
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Human placental villi have essential roles in producing hormones, mediating nutrient and waste exchange, and protecting the fetus from exposure to xenobiotics. Human trophoblast organoids that recapitulate the structure of villi could provid
Externí odkaz:
https://doaj.org/article/7db0c6cab236464e932226adada7bb27
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Phenobarbital (PB) is an archetypal substance used as a mouse hepatocellular carcinoma (HCC) promotor in established experimental protocols. Our previous results showed CAR is the essential factor for PB induced HCC promotion. Subsequent studies sugg
Externí odkaz:
https://doaj.org/article/dedd1b54740847bab9640658a3ba00f5
Autor:
Kouji Ishikawa, Tomohisa Kuroda, Takeshi Hori, Daisuke Iwata, Seijiro Matsuzawa, Jun Nakabayashi, Akira Sasaki, Taketo Ashizawa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Combining genetic heterogeneity and crop homogeneity serves a dual purpose: disease control and maintaining harvest quality. Multilines, which consist of a genetically uniform mixture of plants, have the potential to suppress disease while m
Externí odkaz:
https://doaj.org/article/0edf09b6b1de429194b8d02f7b048e44
Autor:
Norio Kobayashi, Hiroaki Okae, Hitoshi Hiura, Naoto Kubota, Eri H. Kobayashi, Shun Shibata, Akira Oike, Takeshi Hori, Chie Kikutake, Hirotaka Hamada, Hirokazu Kaji, Mikita Suyama, Marie-Line Bortolin-Cavaillé, Jérôme Cavaillé, Takahiro Arima
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Little is known about the epigenetic mechanisms of the first cell fate commitment in humans. Here, the authors show that activation of the miRNA cluster C19MC confers differentiation potential into trophoblast lineages on human embryonic stem cells.
Externí odkaz:
https://doaj.org/article/47848882019749ae9389af9828de45cb
Autor:
Kazuya Yamashita, Serge Ostrovidov, Bibek Raut, Takeshi Hori, Yuji Nashimoto, Nobuhiro Nagai, Toshiaki Abe, Hirokazu Kaji
Publikováno v:
Cell Transplantation, Vol 32 (2023)
Retinal cells are irreparably damaged by diseases such as age-related macular degeneration (AMD). A promising method to restore partial or whole vision is through cell-based transplantation to the damaged location. However, cell transplantation using
Externí odkaz:
https://doaj.org/article/a2d9ea03f3b54b129c23cfeb2cb9364e
Autor:
Serge Ostrovidov, Murugan Ramalingam, Hojae Bae, Gorka Orive, Toshinori Fujie, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji
Publikováno v:
Sensors, Vol 23, Iss 12, p 5625 (2023)
Molecularly imprinted polymers (MIPs) are synthetic polymers with specific binding sites that present high affinity and spatial and chemical complementarities to a targeted analyte. They mimic the molecular recognition seen naturally in the antibody/
Externí odkaz:
https://doaj.org/article/04c3c66193ea40ccbbfc2e2a66cba504
Autor:
Seiichi Mawatari, Kotaro Kumagai, Kohei Oda, Kazuaki Tabu, Sho Ijuin, Kunio Fujisaki, Shuzo Tashima, Yukiko Inada, Hirofumi Uto, Akiko Saisyoji, Yasunari Hiramine, Masafumi Hashiguchi, Tsutomu Tamai, Takeshi Hori, Ohki Taniyama, Ai Toyodome, Haruka Sakae, Takeshi Kure, Kazuhiro Sakurai, Akihiro Moriuchi, Shuji Kanmura, Akio Ido
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
Background The features of hepatitis C virus patients with a sustained virologic response (SVR) who developed hepatocellular carcinoma (HCC) after direct-acting antiviral (DAA) therapy are unclear. Methods The study population included 1494 DAA-SVR p
Externí odkaz:
https://doaj.org/article/a9d631c3572b48d2b03ea489655c1018
Autor:
Kazuaki Tabu, Seiichi Mawatari, Kohei Oda, Kotaro Kumagai, Yukiko Inada, Hirofumi Uto, Akiko Saisyoji, Yasunari Hiramine, Masafumi Hashiguchi, Tsutomu Tamai, Takeshi Hori, Kunio Fujisaki, Dai Imanaka, Takeshi Kure, Ohki Taniyama, Ai Toyodome, Sho Ijuin, Haruka Sakae, Kazuhiro Sakurai, Akihiro Moriuchi, Shuji Kanmura, Akio Ido
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237475 (2020)
Background and aimsDirect-acting antivirals (DAAs) against hepatitis C virus (HCV) exert high anti-HCV activity and are expected to show anti-inflammatory effects associated with HCV elimination. Furthermore, hepatocellular carcinoma (HCC) is known t
Externí odkaz:
https://doaj.org/article/77e19cc7fd2f44569864b15ba39951ef
Autor:
Taketoshi Yasuda, Kayo Suzuki, Yoshiharu Kawaguchi, Shoji Seki, Hiroto Makino, Kenta Watanabe, Takeshi Hori, Tohru Yamagami, Masahiko Kanamori, Tomoatsu Kimura
Publikováno v:
BMC Musculoskeletal Disorders, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Lumbar epidural lipomatosis (LEL) is characterized by abnormal accumulation of unencapsulated adipose tissue in the spinal epidural space. Such accumulation compresses the dural sac and nerve roots, and results in various neurolog
Externí odkaz:
https://doaj.org/article/df63e7cab54c4114baf05eb0d42c2bd1