Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Takeshi Fugono"'
Publikováno v:
The Journal of Antibiotics. 34:1476-1485
The renal excretory mechanism of cefmenoxime in rabbits was compared with that of 6 other cephalosporins (cefotaxime, deacetylcefotaxime, cefotiam, cefazolin, cephaloridine, and cefsulodin). The clearance ratios (Cf-Drug/CInulin=CRf) of cefmenoxime (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003faa9b729daaf14205417c98c1f7f1
https://doi.org/10.7164/antibiotics.34.1476
https://doi.org/10.7164/antibiotics.34.1476
Publikováno v:
The Journal of Antibiotics. 29:928-936
Synthesis and in vitro activity of a number of cephalosporins having alpha-sulfoacyl- or other acyl groups, e.g., alpha-carboxyacyl- and alpha-sulfoaminoacyl- at the 7-position and bearing a variety of heterocyclic thioether or pyridinium moieties at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e4ec24e80602620181b1c153b62a7e
https://doi.org/10.7164/antibiotics.29.928
https://doi.org/10.7164/antibiotics.29.928
Semisynthetic .beta.-lactam antibiotics. 6. Sulfocephalosporins and their antipseudomonal activities
Autor:
Shiro Morimoto, Isao Minami, Takenori Hitaka, Hiroaki Nomura, Toru Masuda, Takeshi Fugono, T. Azuma
Publikováno v:
Journal of Medicinal Chemistry. 17:1312-1315
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::267756fe505114857fc58a6ef7bdf4a0
https://doi.org/10.1021/jm00258a017
https://doi.org/10.1021/jm00258a017
Publikováno v:
The Journal of Antibiotics. 33:1532-1544
The levels of cefmenoxime (SCE-1365) [7 beta-[2-(2-aminothiazol-4-yl)-[Z]-2-methoxyiminoacetamido]-3-[(1-methyl-1H-tetr azol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid] and cefotaxime [7 beta-[2-(2-aminothiazol-4-yl)-[Z]-2-methoxyiminoacetamido]-3-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7fd49926469bd1d227b49d5969afc2
https://doi.org/10.7164/antibiotics.33.1532
https://doi.org/10.7164/antibiotics.33.1532
Publikováno v:
The Journal of Antibiotics. 25:336-342
The plasma level and tissue distribution of sulfocillin administered by intravenous, intraperitoneal, intramuscular or subcutaneous routes into mice, rats, rabbits and dogs, were compared with those of carbenicillin. The drug level was measured as ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::651e269e216d822aadb4eae6299d898d
https://doi.org/10.7164/antibiotics.25.336
https://doi.org/10.7164/antibiotics.25.336
Publikováno v:
The Journal of Antibiotics. 26:146-152
Structure-activity relationships were examined for a number of α-sulfopenicillins and related compounds. Among the α-sulfopenicillins tested, the α-thienyl and α-(p-aminophenyl) homologues showed the greatest activity against Pseudomonas aerugino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70a93764ed1e156147feaf4bd6a55ad1
https://doi.org/10.7164/antibiotics.26.146
https://doi.org/10.7164/antibiotics.26.146
Publikováno v:
Xenobiotica. 2:147-157
1. After intramuscular injection of a new semi-synthetic penicillin, disodium [14C]α-sulphobenzylpenicillin, to rats radioactivity in blood reached a peak at 5 min with a half life of 26 min. Most of the blood radioactivity was not bound to plasma p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9cdc75d886026c98aa5a7c7dcee4e88
https://doi.org/10.3109/00498257209111046
https://doi.org/10.3109/00498257209111046
Publikováno v:
Journal of Medicinal Chemistry. 15:1105-1108
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989298ac9183cf4b044e036a950d1258
https://doi.org/10.1021/jm00281a004
https://doi.org/10.1021/jm00281a004
Autor:
Masahiro Kondo, Toyokazu Kishi, Jisaburo Ueyanagi, Masayuki Muroi, Tai Matsuzawa, Setsuo Harada, Kanji Tsuchiya, Takeshi Fugono
Publikováno v:
Antimicrobial Agents and Chemotherapy. 4:140-148
Maridomycin, a new macrolide antibiotic, and tetrahydromaridomycin were acylated into their mono, di, and tri acyl derivatives. These derivatives were compared with the parent antibiotic, maridomycin, for their (i) in vitro antimicrobial activities,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b62aa83f6bc708cd66b95cb448bc01
https://doi.org/10.1128/aac.4.2.140
https://doi.org/10.1128/aac.4.2.140
Autor:
Shiro Morimoto, Hiroaki Nomura, Takeshi Fugono, Toshiyuki Azuma, Isao Minami, Masatake Hori, Toru Masuda
Publikováno v:
Journal of Medicinal Chemistry. 15:1108-1111
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04a3a987d99f64bc0685e0c3162413df
https://doi.org/10.1021/jm00281a005
https://doi.org/10.1021/jm00281a005