Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Takeshi Annoura"'
Publikováno v:
Saudi Pharmaceutical Journal, Vol 32, Iss 6, Pp 102085- (2024)
This review discusses the potential of liposomes as drug delivery systems for antimalarial therapies. Malaria continues to be a significant cause of mortality and morbidity, particularly among children and pregnant women. Drug resistance due to patie
Externí odkaz:
https://doaj.org/article/fc3ce310ec7e492b9ba3c310270c2f69
Autor:
Sayuri Nakamae, Satoshi Miyagawa, Koki Ogawa, Mariko Kamiya, Mayumi Taniguchi, Akari Ono, Maho Kawaguchi, Awet Alem Teklemichael, Jiun-Yu Jian, Tamasa Araki, Yukimi Katagami, Hidefumi Mukai, Takeshi Annoura, Katsuyuki Yui, Kenji Hirayama, Shigeru Kawakami, Shusaku Mizukami
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Recent studies have suggested that CD8+ liver-resident memory T (TRM) cells are crucial in the protection against liver-stage malaria. We used liver-directed mRNA-containing lipid nanoparticles (mRNA-LNPs) to induce liver TRM cells in a murine model.
Externí odkaz:
https://doaj.org/article/1b09044e3da34316bfd14951a1d5b2ae
Autor:
Nguyen Quang Thieu, Vu Duc Chinh, Truong Van Hanh, Nguyen Van Dung, Hidekazu Takagi, Takeshi Annoura, Satoru Kawai, Gaku Masuda, Nguyen Van Tuan, Vu Viet Hung, Shusuke Nakazawa, Richard Culleton, Nguyen Thi Huong Binh, Yoshimasa Maeno
Publikováno v:
Tropical Medicine and Health, Vol 50, Iss 1, Pp 1-7 (2022)
Abstract Background Plasmodium falciparum has acquired resistance to artemisinin in Southeast Asia, with mutations in the P. falciparum Kelch-13 (Pfk13) gene associated with the resistance phenotype. The widespread use of Artemisinin-based combinatio
Externí odkaz:
https://doaj.org/article/117e6812b15c4be3ae29c9e7728e3220
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Externí odkaz:
https://doaj.org/article/b5829483cf31443c82f8212001734b59
Autor:
Vu Duc Chinh, Gaku Masuda, Vu Viet Hung, Hidekazu Takagi, Satoru Kawai, Takeshi Annoura, Yoshimasa Maeno
Publikováno v:
Tropical Medicine and Health, Vol 47, Iss 1, Pp 1-6 (2019)
Abstract Background Human malaria is a major threat in rural communities of central Vietnam. Anopheles dirus and Anopheles minimus species are critical malaria vectors in Vietnam, which transmit Plasmodium parasites. However, the entomological aspect
Externí odkaz:
https://doaj.org/article/795a4879c23b44b898eb47d0ccc21892
Autor:
Arif Nurkanto, Ghulam Jeelani, Herbert J. Santos, Yulia Rahmawati, Mihoko Mori, Yumi Nakamura, Kana Goto, Yoko Saikawa, Takeshi Annoura, Yuzuru Tozawa, Takaya Sakura, Daniel Ken Inaoka, Kazuro Shiomi, Tomoyoshi Nozaki
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Coenzyme A (CoA) is a well-known cofactor that plays an essential role in many metabolic reactions in all organisms. In Plasmodium falciparum, the most deadly among Plasmodium species that cause malaria, CoA and its biosynthetic pathway have been pro
Externí odkaz:
https://doaj.org/article/27764de5f3c2464089e06478fbe753a2
Autor:
Izumi Taku, Tomohiro Hirai, Takashi Makiuchi, Naoaki Shinzawa, Shiroh Iwanaga, Takeshi Annoura, Kisaburo Nagamune, Tomoyoshi Nozaki, Yumiko Saito-Nakano
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2021)
Plasmodium falciparum extensively remodels human erythrocytes by exporting hundreds of parasite proteins. This remodeling is closely linked to the Plasmodium virulence-related functions and immune evasion. The N-terminal export signal named PEXEL (Pl
Externí odkaz:
https://doaj.org/article/1c417b4a961643819c12368416d5d7c7
Autor:
Surendra Kumar, Kolli, Alvaro, Molina-Cruz, Tamasa, Araki, Fiona J A, Geurten, Jai, Ramesar, Severine, Chevalley-Maurel, Hans J, Kroeze, Sascha, Bezemer, Clarize, de Korne, Roxanne, Withers, Nadia, Raytselis, Angela F, El Hebieshy, Robbert Q, Kim, Matthew A, Child, Soichiro, Kakuta, Hajime, Hisaeda, Hirotaka, Kobayashi, Takeshi, Annoura, Paul J, Hensbergen, Blandine M, Franke-Fayard, Carolina, Barillas-Mury, Ferenc A, Scheeren, Chris J, Janse
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(35)
Glutaminyl cyclase (QC) modifies N-terminal glutamine or glutamic acid residues of target proteins into cyclic pyroglutamic acid (pGlu). Here, we report the biochemical and functional analysis of
Publikováno v:
ACS Infectious Diseases. 8:457-462
Autor:
Arif Nurkanto, Riyo Imamura, Yulia Rahmawati, Erwahyuni Endang Prabandari, Danang Waluyo, Takeshi Annoura, Kazuki Yamamoto, Masakazu Sekijima, Yuki Nishimura, Takayoshi Okabe, Tomoo Shiba, Norio Shibata, Hirotatsu Kojima, James Duffy, Tomoyoshi Nozaki
Publikováno v:
Antimicrobial Agents and Chemotherapy. 66
Malaria is a mosquito-borne fatal infectious disease that affects humans and is caused by Plasmodium parasites, primarily Plasmodium falciparum . Widespread drug resistance compels us to discover novel compounds and alternative drug discovery targets