Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Takeshi, Tominaga"'
Publikováno v:
Practica Oto-Rhino-Laryngologica. 111:93-99
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55c32684da241894c28465363f58c104
https://doi.org/10.5631/jibirin.111.93
https://doi.org/10.5631/jibirin.111.93
Autor:
Dai Miyazaki, Yoshitsugu Inoue, Waka Ishida, Koudai Inata, Atsuki Fukushima, Shin-ichi Sasaki, Takeshi Tominaga, Sachiko Mihara, Keiko Yakura
Publikováno v:
The American Journal of Pathology. 183:96-107
Pharmacologic inhibitors of IκB kinase (IKK), especially IKK-β, have been developed to treat inflammatory diseases. However, their interactions with components of the NF-κB pathways are not fully known in allergic diseases. To examine whether IKK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6075054d3707514853099bab6113aad
https://doi.org/10.1016/j.ajpath.2013.04.006
https://doi.org/10.1016/j.ajpath.2013.04.006
Autor:
Chika Nakamura, Koichiro Nojiri, Yoshiharu Sunaga, Tsuyoshi Yoshikawa, Yasuharu Nakanishi, Kazuhide Iwasaki, Hiroyuki Yamashita, Yasuhiro Uno, Takeshi Tominaga, Hiroshi Yamazaki, Atsunobu Muneoka, Masahiro Utoh
Publikováno v:
Drug Metabolism and Pharmacokinetics. 28:510-513
Cynomolgus macaques, used in drug metabolism studies due to their evolutionary closeness to humans, are mainly bred in Asian countries, including Cambodia, China, and Indonesia. Cytochromes P450 (P450s) are important drug-metabolizing enzymes, presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c906e3fc02aadb42745b3a2b6429fced
https://doi.org/10.2133/dmpk.dmpk-13-nt-031
https://doi.org/10.2133/dmpk.dmpk-13-nt-031
Publikováno v:
Japanese Journal of Ophthalmology. 54:476-480
To investigate whether Staphylococcus enterotoxin B (SEB) affects the early-phase reaction (EPR) in experimental conjunctivitis. Nc/Nga mice were sensitized to ragweed (RW) or phosphate-buffered saline (PBS) in alum. The mice were subsequently treate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66c4abb3995780b398e6f2d04cea98c
https://doi.org/10.1007/s10384-010-0837-6
https://doi.org/10.1007/s10384-010-0837-6
Autor:
Yoshitsugu Inoue, Fu-Tong Liu, Dai Miyazaki, Atsuki Fukushima, Marc E. Rothenberg, Takeshi Tominaga, Takao Nakamura, Masaharu Ohbayashi, Hidemitsu Higashi, Chuan Hui Kuo, Santa Jeremy Ono, Meguru Murata, Shuzo Takeda, Naoki Komatsu, Keiko Yakura
Publikováno v:
International Immunology. 21:187-201
The immune response is regulated, in part, by effector cells whose activation requires multiple signals. For example, T cells require signals emanating from the T cell antigen receptor and co-stimulatory molecules for full activation. Here, we presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2941d56df0cde624a85acbb8170b60d
https://doi.org/10.1093/intimm/dxn137
https://doi.org/10.1093/intimm/dxn137
Autor:
Yasuo Ohashi, Takashi Takahashi, Takeshi Tominaga, Susumu Kodaira, Masayuki Yasutomi, Masahiko Watanabe, Tomoyuki Kato, Kazufumi Kunitomo, Hiroharu Isomoto, Keiichi Hojo
Publikováno v:
Langenbeck's Archives of Surgery. 391:330-337
The purpose of the present trial was to clarify the efficacy of postoperative adjuvant chemotherapy including an oral fluoropyrimidine anticancer drug, the 1-hexylcarbamoyl-5-fluorouracil (HCFU), for the treatment of colon cancer. Patients with clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41f3c2fc83788329cc4a67a55ad9e2a
https://doi.org/10.1007/s00423-006-0044-6
https://doi.org/10.1007/s00423-006-0044-6
Publikováno v:
British Journal of Surgery. 91:38-43
Background In addition to mastectomy, level II and level III axillary node dissection procedures are performed widely in Japan. A randomized clinical trial was performed to determine which procedure was more effective. Methods One group of women had
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc3af4561a120219580f41f2e201238
https://doi.org/10.1002/bjs.4372
https://doi.org/10.1002/bjs.4372
Autor:
Tomohisa Sekine, Nobuyuki Yamamoto, Masakazu Toi, Gyo Asai, Takeshi Tominaga, Morihiko Kimura, Yasuo Nomura, Shigemitsu Takashima, Kiyoshi Nishiyama, Eisei Shin
Publikováno v:
Cancer Chemotherapy and Pharmacology. 49:468-472
The aim of this study was to analyze the pharmacokinetics and pharmacodynamics (PK/PD) of 6- O-(3-ethoxypropionyl)-3',4'- O-exo-benzylidene-chartreusin (IST-622) and its metabolites, and to develop limited sampling models (LSM). Based on the data fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069134eb3f0fe9526437625d90785686
https://doi.org/10.1007/s00280-002-0455-1
https://doi.org/10.1007/s00280-002-0455-1
Autor:
Takeshi Tominaga, Morihiko Kimura
Publikováno v:
Breast Cancer. 9:153-159
In 1999 European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States and National Cancer Institute of Canada published Response Evaluation Criteria in Solid Tumors (RECIST) as a revision of the WHO criter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6664b19f3662c894962a965224c746c0
https://doi.org/10.1007/bf02967580
https://doi.org/10.1007/bf02967580
Autor:
Takeshi Tominaga, Atsushi Yokota, Hideki Tachibana, Daisuke Horii, Yasuo Noda, Shin-ichi Segawa, Yoshiaki Tanisaka
Publikováno v:
Biochemistry. 41:2130-2139
The 15N-labeled recombinant hen lysozyme and two species of two-disulfide variants, denoted as 2SS[6-127, 30-115] and 2SS[64-80, 76-94], were studied by means of NMR spectroscopy. The former variant contains two disulfide bridges in the alpha-domain,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d2bd2960dcdaeac7942672211a934f
https://doi.org/10.1021/bi0113418
https://doi.org/10.1021/bi0113418