Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Takeo, TANAKA"'
Autor:
Saori Shimoyama‐Ibuki, Satoshi Iyama, Yoshiya Ohashi, Kento Ono, Yusuke Sugama, Chisa Fujita, Akari Goto, Hiroto Horiguchi, Akihito Fujimi, Takeo Tanaka, Kohichi Takada, Koh‐Ichi Sakata, Masayoshi Kobune
Publikováno v:
eJHaem, Vol 5, Iss 5, Pp 1038-1042 (2024)
Abstract Introduction To diagnose sinusoidal obstruction syndrome/veno‐occlusive disease (SOS/VOD), transabdominal ultrasonography is usually used to detect hemodynamic changes, but we tried to detect the changes using four‐dimensional computed t
Externí odkaz:
https://doaj.org/article/634b98b1fa63486386efaf1281b81428
Autor:
Yumie Takeshita, Takeo Tanaka, Hiroaki Takayama, Yuki Kita, Hisanori Goto, Yujiro Nakano, Yoshiro Saito, Toshinari Takamura
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 2, Pp 230-235 (2023)
Abstract Aims/Introduction Selenoprotein P (SeP; encoded by SEPP1 in humans) is a hepatokine that causes impaired insulin secretion and insulin resistance. Metformin downregulates SELENOP promoter activity through an adenosine monophosphate‐activat
Externí odkaz:
https://doaj.org/article/f11bd1d0f77a406c927decd1223b8bb0
Autor:
Yumie Takeshita, Yuki Kita, Takeo Tanaka, Hisanori Goto, Yujiro Nakano, Chisato Teramura, Yasufumi Enyama, Toshinari Takamura, the Establishment of Rationale for Antiaging Diabetic Medicine (ERA‐DM) Study Group
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 6, Pp 965-974 (2022)
Abstract Aims/Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) might be less effective in patients with severe hyperglycemia, because hyperglycemia downregulated the GLP‐1 receptor in an animal study. To examine this hypothes
Externí odkaz:
https://doaj.org/article/eaedd379a2fb4663bf3d9039c36984f1
Autor:
Yumie Takeshita, Chisato Teramura, Kyoko Kamoshita, Hiroaki Takayama, Hiromi Nakagawa, Yasufumi Enyama, Kiyo‐Aki Ishii, Takeo Tanaka, Hisanori Goto, Yujiro Nakano, Sachie Osada, Yoshiaki Tanaka, Kumpei Tokuyama, Toshinari Takamura
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 3, Pp 532-542 (2022)
ABSTRACT Aim Selenoprotein P (SeP, encoded by SELENOP in humans) is a hepatokine that causes insulin resistance in the liver and skeletal muscle. It was found that polyunsaturated fatty acid eicosapentaenoic acid (EPA) downregulates Selenop expressio
Externí odkaz:
https://doaj.org/article/2291939474354f1ba9a6bcaefcac3fa8
Autor:
Yumie Takeshita, Takeo Tanaka, Hitomi Wakakuri, Yuki Kita, Takehiro Kanamori, Toshinari Takamura
Publikováno v:
Journal of Diabetes Investigation, Vol 12, Iss 7, Pp 1193-1201 (2021)
Abstract Aims/Introduction This study compares the effects of two different insulin regimens – basal versus bolus insulin – on metabolic and cardiovascular autonomic function in Japanese participants with type 2 diabetes. Materials and Methods Pa
Externí odkaz:
https://doaj.org/article/b92b3bf1d58b433baac98da2c62214a7
Autor:
Noboru Takata, Kiyo-aki Ishii, Hiroaki Takayama, Mayumi Nagashimada, Kyoko Kamoshita, Takeo Tanaka, Akihiro Kikuchi, Yumie Takeshita, Yukako Matsumoto, Tsuguhito Ota, Yasuhiko Yamamoto, Satoshi Yamagoe, Akihiro Seki, Yoshio Sakai, Shuichi Kaneko, Toshinari Takamura
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract It remains unclear how hepatic steatosis links to inflammation. Leukocyte cell-derived chemotaxin 2 (LECT2) is a hepatokine that senses fat in the liver and is upregulated prior to weight gain. The aim of this study was to investigate the si
Externí odkaz:
https://doaj.org/article/e247c50a13e443be9ca0d4e1e98cbdad
Autor:
Kohei Harada, Tomohiro Ishinuki, Yoshiya Ohashi, Takeo Tanaka, Ayaka Chiba, Kanako Numasawa, Tatsuya Imai, Shun Hayasaka, Takahito Tsugiki, Koji Miyanishi, Minoru Nagayama, Ichiro Takemasa, Junji Kato, Toru Mizuguchi
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
Although the liver is a regenerating organ, excessive loss of liver volume (LV) can cause fatal liver failure. It is unclear whether LV is correlated with age; however, it is known that liver function decreases with age. In addition, the gender-relat
Externí odkaz:
https://doaj.org/article/f796d32426874c939024e274e4483dc8
Autor:
Chiaki, Nomura, Yujiro, Nakano, Takeo, Tanaka, Kosuke Robert, Shima, Mitsuhiro, Kometani, Takehiro, Kanamori, Hiroko, Ikeda, Yumie, Takeshita, Takashi, Yoneda, Toshinari, Takamura
Publikováno v:
Internal Medicine. 61:3693-3698
Localization of ectopic cyclic Cushing's syndrome, which causes life-threatening complications, is challenging. A 70-year-old woman showed cyclic hypokalemia and hyperglycemia and was diagnosed with cyclic ectopic Cushing's syndrome. Although somatos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a39dc11771130619595c3e10ac88a3e5
https://doi.org/10.2169/internalmedicine.9238-21
https://doi.org/10.2169/internalmedicine.9238-21
Autor:
Yumie Takeshita, Masao Honda, Kenichi Harada, Yuki Kita, Noboru Takata, Hiromasa Tsujiguchi, Takeo Tanaka, Hisanori Goto, Yujiro Nakano, Noriho Iida, Kuniaki Arai, Tatsuya Yamashita, Eishiro Mizukoshi, Hiroyuki Nakamura, Shuichi Kaneko, Toshinari Takamura
Publikováno v:
Diabetes Care. 45:2064-2075
OBJECTIVE Nonalcoholic fatty liver disease (NAFLD) is a liver phenotype of type 2 diabetes and obesity. Currently, the efficacy of sodium–glucose cotransporter 2 (SGLT2) inhibitors and sulfonylureas in liver pathology and hepatic gene expression pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b17d01751e39383eea473ea85a4c74
https://doi.org/10.2337/dc21-2049
https://doi.org/10.2337/dc21-2049
Autor:
Kyoko Kamoshita, Yumie Takeshita, Hiromi Nakagawa, Kiyo-aki Ishii, Sachie Osada, Chisato Teramura, Hiroaki Takayama, Yujiro Nakano, Hisanori Goto, Toshinari Takamura, Yasufumi Enyama, Takeo Tanaka, Yoshiaki Tanaka, Kumpei Tokuyama
Publikováno v:
Journal of Diabetes Investigation. 13:532-542
AIM Selenoprotein P (SeP, encoded by SELENOP in humans) is a hepatokine that causes insulin resistance in the liver and skeletal muscle. It was found that polyunsaturated fatty acid eicosapentaenoic acid (EPA) downregulates Selenop expression by inac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8abb6db5d32a9df88fdaa13b8153dc
https://doi.org/10.1111/jdi.13699
https://doi.org/10.1111/jdi.13699