Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Takeo, Nakaya"'
Autor:
Yuki Taguchi, Takeo Nakaya, Kenichi Aizawa, Yoshiyuki Noguchi, Nobuhiko Maiya, Chisako Iwamoto, Kenichi Ohba, Minoru Sugawara, Masayuki Murata, Ryozo Nagai, Fumi Kano
Publikováno v:
FEBS Open Bio, Vol 14, Iss 4, Pp 695-720 (2024)
The peptide mimetic, NC114, is a promising anticancer compound that specifically kills colorectal cancer cells without affecting normal colon epithelial cells. In our previous study, we observed that NC114 inhibited the Wnt/β‐catenin pathway, with
Externí odkaz:
https://doaj.org/article/2ffa86450f6b42db85fe0bbacf267b30
Autor:
Yuma Horii, Shoichi Matsuda, Chikashi Toyota, Takumi Morinaga, Takeo Nakaya, Soken Tsuchiya, Masaki Ohmuraya, Takanori Hironaka, Ryo Yoshiki, Kotaro Kasai, Yuto Yamauchi, Noburo Takizawa, Akiomi Nagasaka, Akira Tanaka, Hidetaka Kosako, Michio Nakaya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Heart fibrosis involves a feedback loop where stiffening increases fibrosis-related gene expression in myofibroblasts. Here authors reveal the mechanosensitive nuclear translocation of VGLL3, where it phase separates and promotes collagen production,
Externí odkaz:
https://doaj.org/article/3d91cd5901fb4a358a83f06efa607833
Autor:
Kiyokuni Tanabe, Kensuke Yokoyama, Atsushi Kanno, Eriko Ikeda, Kozue Ando, Hiroki Nagai, Takahiro Koyanagi, Mio Sakaguchi, Takeo Nakaya, Kiichi Tamada, Toshiro Niki, Noriyoshi Fukushima, Lefor, Alan Kawarai, Hironori Yamamoto
Publikováno v:
Internal Medicine; 2024, Vol. 63 Issue 6, p791-798, 8p
Autor:
Yoko Fujimoto, Hironori Takahashi, Kenji Horie, Takeo Nakaya, Toshiro Niki, Hiroyuki Fujiwara, Shigeki Matsubara
Publikováno v:
Case Reports in Obstetrics and Gynecology, Vol 2019 (2019)
We describe a patient with bilateral cystic tumors of the pelvis. The left one rapidly grew during pregnancy and combined with the right one, whose clinical course made diagnosis difficult. A pregnant woman with a history of laparotomy was referred t
Externí odkaz:
https://doaj.org/article/f16108b2b7ac4279bde68c017739e189
Autor:
Ryozo Nagai, Masahiko Kuroda, Masashi Fukayama, Hans Clevers, Kazuki Nakao, Makoto M. Taketo, Toshiro Sato, Masashi Sanada, Masami Tanaka, Ichiro Manabe, Seishi Ogawa, Takeo Nakaya
PDF file - 674KB, Experimental design for the sorting of stem cells and TA cells from the duodenum of Lgr5-GFP-IRES-CreERT mice (Lgr5 Cre+ Catnb+/lox(ex3) Klf5flox/flox, Lgr5 Cre+ Catnb+/lox(ex3) Klf5+/+, and Lgr5 Cre+ Klf5flox/flox) for mRNA express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e57ac84f1254226ac5bef2811aeec00e
https://doi.org/10.1158/0008-5472.22400132
https://doi.org/10.1158/0008-5472.22400132
Autor:
Masashi Fukayama, Kenzo Takada, Takashi Sakatani, Takeo Nakaya, Teppei Morikawa, Shumpei Ishikawa, Aya Shinozaki, Tetsuo Ushiku, Noriko Murakami, Hiroshi Uozaki, Rumi Hino
Supplementary Table 1 from Activation of DNA Methyltransferase 1 by EBV Latent Membrane Protein 2A Leads to Promoter Hypermethylation of PTEN Gene in Gastric Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021bd343c895ee955230d734eb8ceb3e
https://doi.org/10.1158/0008-5472.22381038
https://doi.org/10.1158/0008-5472.22381038
Autor:
Ryozo Nagai, Masahiko Kuroda, Masashi Fukayama, Hans Clevers, Kazuki Nakao, Makoto M. Taketo, Toshiro Sato, Masashi Sanada, Masami Tanaka, Ichiro Manabe, Seishi Ogawa, Takeo Nakaya
The intestinal epithelium maintains homeostasis by a self-renewal process involving resident stem cells, including Lgr5+ crypt-base columnar cells, but core mechanisms and their contributions to intestinal cancer are not fully defined. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b45759ca3a30b6d923edf178ed51238
https://doi.org/10.1158/0008-5472.c.6505502
https://doi.org/10.1158/0008-5472.c.6505502
Autor:
Ryozo Nagai, Masahiko Kuroda, Masashi Fukayama, Hans Clevers, Kazuki Nakao, Makoto M. Taketo, Toshiro Sato, Masashi Sanada, Masami Tanaka, Ichiro Manabe, Seishi Ogawa, Takeo Nakaya
XLS file - 1363KB, Supplementary Table 1. Genes downregulated following the inducible deletion of Klf5 in the duodenal stem cells of Lgr5-EGFP-ires-CreERT2 Catnblox(deltaex3) Klfflox/flox mice, compared with Lgr5-EGFPires-CreERT2 atnblox(deltaex3) Kl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8c8d6ceecd3b4332273df68e705fbe
https://doi.org/10.1158/0008-5472.22400114
https://doi.org/10.1158/0008-5472.22400114
Autor:
Masashi Fukayama, Kenzo Takada, Takashi Sakatani, Takeo Nakaya, Teppei Morikawa, Shumpei Ishikawa, Aya Shinozaki, Tetsuo Ushiku, Noriko Murakami, Hiroshi Uozaki, Rumi Hino
CpG island promoter methylation of tumor suppressor genes is one of the most characteristic abnormalities in EBV-associated gastric carcinoma (GC). Aberrant promoter methylation and expression loss of PTEN were evaluated in cancer tissues of GC by me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13db4e49098228da6ebcf9d82949a5ee
https://doi.org/10.1158/0008-5472.c.6499740.v1
https://doi.org/10.1158/0008-5472.c.6499740.v1
Autor:
Ryozo Nagai, Masahiko Kuroda, Masashi Fukayama, Hans Clevers, Kazuki Nakao, Makoto M. Taketo, Toshiro Sato, Masashi Sanada, Masami Tanaka, Ichiro Manabe, Seishi Ogawa, Takeo Nakaya
PDF file - 123KB, mRNA expression signal intensities in stem cells of the duodenum of Lgr5 Cre+ Klf5flox/flox mice without Klf5 deletion (x-axis, log) and Lgr5 Cre+ Klf5delta/delta mice (with Klf5 2 deletion) (y-axis, log).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16fa91d3876446371306838e497e702
https://doi.org/10.1158/0008-5472.22400129
https://doi.org/10.1158/0008-5472.22400129