Phase II trial evaluating the long-term efficacy and peripheral sensory neuropathy of capecitabine plus oxaliplatin (XELOX) as adjuvant therapy in Japanese patients with operated stage III colon cancer.

Autor: Hata T; Department of Surgery, Japan Organization of Occupational Health and Safety, Kansai Rosai Hospital, 3-1-69 Inabaso, Amagasaki, Hyogo, 660-8511, Japan. hata-taishi@kansaih.johas.go.jp., Uemura M; Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan., Danno K; Department of Surgery, Minoh City Hospital, Mino, Osaka, Japan., Yoshioka S; Department of Surgery, Yao Municipal Hospital, Osaka, Japan., Matsuda C; Department of Surgery, Osaka Police Hospital, Osaka, Japan., Kagawa Y; Department of Surgery, Osaka General Medical Center, Osaka, Japan., Shingai T; Department of Surgery, Saiseikai Senri Hospital, Suita, Japan., Suzuki Y; Department of Surgery, Toyonaka Municipal Hospital, Toyonaka, Japan., Tei M; Department of Surgery, Osaka Rosai Hospital, Sakai, Japan., Tanida T; Department of Surgery, Higashiosaka City Medical Center, Higashiosaka , Japan., Komori T; Department of Surgery, Hyogo Prefectural Nishinomiya Hospital, Nishinomiya, Japan., Okamura S; Department of Gastroenterological Surgery, Suita Municipal Hospital, Suita, Japan., Ota H; Department of Surgery, Ikeda City Hospital, Ikeda, Japan., Takemoto H; Department of Surgery, Kinki Central Hospital of the Mutual Aid Association of Public School Teachers, Itami, Japan., Ogino T; Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan., Miyoshi N; Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan., Yamamoto H; Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan., Murata K; Department of Surgery, Japan Organization of Occupational Health and Safety, Kansai Rosai Hospital, 3-1-69 Inabaso, Amagasaki, Hyogo, 660-8511, Japan., Doki Y; Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan., Eguchi H; Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.

Publikováno v: Scientific reports [Sci Rep] 2024 Nov 02; Vol. 14 (1), pp. 26434. Date of Electronic Publication: 2024 Nov 02.

Soluble form of Lingo2, an autism spectrum disorder-associated molecule, functions as an excitatory synapse organizer in neurons.

Autor: Yoshida F; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Nagatomo R; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Utsunomiya S; Neuroscience 2, Laboratory for Drug Discovery and Disease Research, Shionogi & Co. Ltd, Osaka, Japan., Kimura M; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Shun S; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Kono R; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Kato Y; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Nao Y; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Maeda K; Neuroscience 2, Laboratory for Drug Discovery and Disease Research, Shionogi & Co. Ltd, Osaka, Japan., Koyama R; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.; Institute for AI and Beyond, The University of Tokyo, Tokyo, Japan.; 5Department of Translational Neurobiology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan., Ikegaya Y; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.; Institute for AI and Beyond, The University of Tokyo, Tokyo, Japan.; Center for Information and Neural Networks, National Institute of Information and Communications Technology, Osaka, Japan., Lichtenthaler SF; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Takatori S; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Takemoto H; Neuroscience 2, Laboratory for Drug Discovery and Disease Research, Shionogi & Co. Ltd, Osaka, Japan.; Business-Academia Collaborative Laboratory (Shionogi), Graduate School of Pharmaceutical Science, The University of Tokyo, Tokyo, Japan., Ogawa K; Neuroscience 2, Laboratory for Drug Discovery and Disease Research, Shionogi & Co. Ltd, Osaka, Japan., Ito G; Department of Biomolecular Chemistry, Faculty of Pharma-Science, Teikyo University, Tokyo, Japan.; Social Cooperation Program of Brain and Neurological Disorders, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Tomita T; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan. taisuke@mol.f.u-tokyo.ac.jp.; Social Cooperation Program of Brain and Neurological Disorders, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan. taisuke@mol.f.u-tokyo.ac.jp.

Publikováno v: Translational psychiatry [Transl Psychiatry] 2024 Oct 23; Vol. 14 (1), pp. 448. Date of Electronic Publication: 2024 Oct 23.

Verrucous gastritis-like lesion in intramucosal Helicobacter pylori-uninfected signet ring cell carcinoma with poorly differentiated adenocarcinoma.

Autor: Takemoto H; Department of Gastroenterology, Hiroshima University Hospital, 1-2-3 Kasumi, Minamiku, Hiroshima, 734-8553, Japan., Kotachi T; Department of Gastroenterology, Hiroshima University Hospital, 1-2-3 Kasumi, Minamiku, Hiroshima, 734-8553, Japan. ooi0926yuyu@gmail.com., Teshima H; Department of Gastroenterology, Hiroshima University Hospital, 1-2-3 Kasumi, Minamiku, Hiroshima, 734-8553, Japan., Tamari H; Department of Gastroenterology, Hiroshima University Hospital, 1-2-3 Kasumi, Minamiku, Hiroshima, 734-8553, Japan., Tsuboi A; Department of Gastroenterology, Hiroshima University Hospital, 1-2-3 Kasumi, Minamiku, Hiroshima, 734-8553, Japan., Tanaka H; Department of Gastroenterology, Hiroshima University Hospital, 1-2-3 Kasumi, Minamiku, Hiroshima, 734-8553, Japan., Yamashita K; Department of Gastroenterology, Hiroshima University Hospital, 1-2-3 Kasumi, Minamiku, Hiroshima, 734-8553, Japan., Urabe Y; Department of Gastrointestinal Endoscopy and Medicine, Hiroshima University Hospital, Hiroshima, Japan., Ishikawa A; Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan., Oka S; Department of Gastroenterology, Hiroshima University Hospital, 1-2-3 Kasumi, Minamiku, Hiroshima, 734-8553, Japan.

Publikováno v: Clinical journal of gastroenterology [Clin J Gastroenterol] 2024 Jun; Vol. 17 (3), pp. 412-418. Date of Electronic Publication: 2024 Mar 23.

Thermo-Responsive Polymer-siRNA Conjugates Enabling Artificial Control of Gene Silencing around Body Temperature.

Autor: Honda Y; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan.; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan.; Innovation Center of Nanomedicine (iCONM), Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-0821, Japan., Onodera S; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan.; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan., Takemoto H; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan.; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan., Harun NFC; Universiti Kuala Lumpur - Branch Campus Malaysian Institute of Chemical and Bioengineering Technology, Lot 1988, Vendor City, Taboh Naning, 78000, Alor Gajah, Melaka, Malaysia., Nomoto T; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan.; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan., Matsui M; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan., Tomoda K; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan., Sun Y; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan.; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan., Miura Y; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan.; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan., Nishiyama N; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan. nishiyama.n.ad@m.titech.ac.jp.; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa, 226-8503, Japan. nishiyama.n.ad@m.titech.ac.jp.; Innovation Center of Nanomedicine (iCONM), Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-0821, Japan. nishiyama.n.ad@m.titech.ac.jp.

Publikováno v: Pharmaceutical research [Pharm Res] 2023 Jan; Vol. 40 (1), pp. 157-165. Date of Electronic Publication: 2022 Oct 28.

Programmed immobilization of living cells using independent click pairs.

Autor: Zhu C; Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-8501, Japan., Takemoto H; Medical Chemistry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, 606-0823, Japan., Higuchi Y; Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-8501, Japan. Electronic address: higuchi.yuriko.6v@kyoto-u.ac.jp., Yamashita F; Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-8501, Japan; Department of Applied Pharmaceutics and Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-8501, Japan.

Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Mar 05; Vol. 699, pp. 149556. Date of Electronic Publication: 2024 Jan 22.