Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Takemi Kinouchi"'
Autor:
Keiko Kataoka, Tomomi Kuwahara, Usanee Vinitketkumnuen, Masami Yamada, Shigeru Akimoto, Takemi Kinouchi, Yoshinari Ohnishi, Takehiko Nohmi, Masanori Mazaki
Publikováno v:
The journal of medical investigation : JMI. 53(1-2):123-133
To elucidate the mechanism of antimutagenicity of caraway, weexaminedtheeffects of caraway seed extract on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced mutagenesis in DNA methyltransferase-deficient Salmonella typhimurium strains, O 6 ‑methy
Autor:
Hisanori Uehara, Takamasa Yamada, Yoshifumi Chone, Keisuke Kitaura, Takanori Minami, Yoshimi Bando, Zhongxian Jiao, Yoshinari Ohnishi, Masataka Mochizuki, Keisuke Izumi, Yasuo Suzuki, Takemi Kinouchi
Publikováno v:
Japanese Journal of Cancer Research : Gann
We studied the susceptibilities to N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine (BBN)‐induced urinary bladder carcinogenesis of male Long‐Evans Cinnamon (LEC), F344 and Long‐Evans Agouti (LEA) rats. Male rats (n=21) were given 0.1% BBN in thei
Autor:
Tomomi Kuwahara, Takemi Kinouchi, Minoru Higashimoto, Yoshinari Ohnishi, Y. Akada, Masao Sato
Publikováno v:
Food and Chemical Toxicology. 38:7-13
It has been shown that the mutagenicity of 1-methyl-1,2,3, 4-tetrahydro-beta-carboline-3-carboxylic acid (MTCCA), a major mutagen precursor in soy sauce on treatment with nitrite and ethanol, was strongly decreased by the addition of hot water extrac
Autor:
Isao Hiraoka, Tomomi Kuwahara, Yoshinari Ohnishi, Shan Ruo Bing, Motoo Uejima, Takemi Kinouchi, Shigeru Akimoto, Haruyuki Nakayama, Keiko Kataoka, Kazuyuki Shimono
Publikováno v:
Microbiology and Immunology. 42:347-355
A nonsteroidal antiinflammatory drug, 5-bromo-2-(4-fluorophenyl)-3-(4-methylsulfonylphenyl) thiophene (BFMeT), induced ileal ulcers in rats after oral administration, while no ulcers were observed after subcutaneous injection. The ileal ulcer formati
Autor:
Takashi Kuhara, Kaname Okada, Takemi Kinouchi, Yoshinari Ohnishi, Shoji Kagami, Masao Hirose, Yuri Tominaga
Publikováno v:
Journal of the Japanese Association for Infectious Diseases. 72:162-166
Autor:
Yasumasa Monden, Aiichiro Kajikawa, Takemi Kinouchi, Mohammed Jabed Seraj, Atsushi Umemoto, Seiji Mimura, Yoshinari Ohnishi
Publikováno v:
Cancer Letters. 115:97-103
The present study has demonstrated the influence of bile acids (BAs) on the development and growth of azoxymethane (AOM)-induced aberrant crypt foci (ACF). Male F344 rats were treated with two doses of AOM (15 mg/kg) at 7 days apart and fed either ba
Autor:
Takemi Kinouchi, Hideki Arimochi, Usanee Vinitketkumnuen, Ratchada Suaeyun, Yoshinari Ohnishi
Publikováno v:
Carcinogenesis. 18:949-955
The 80%-ethanol extract of lemon grass (Cymbopogon citratus Stapf), a medicinal plant in Thailand, has been reported to be antimutagenic against various known mutagens in the Salmonella mutation assay. To investigate chemoprevention in an animal carc
Autor:
Yoshiko Matsuda, Haruyuki Nakayama, Yoshinari Ohnishi, Takemi Kinouchi, Keiko Kataoka, Shigeru Akimoto
Publikováno v:
Pharmacogenetics. 7:35-43
Sorivudine, 1-beta-D-arabinofuranosyl-5-(E)-(2-bromovinyl)uracil, is a potent antiviral agent against varicella-zoster virus and herpes simplex virus type 1. However, sorivudine should not be used in combination with anticancer drugs such as 5-fluoro
Publikováno v:
Microbiology and Immunology. 40:553-560
The role of intestinal bacteria in induction and repression of ulcer formation in the ileum of rats treated with one of the nonsteroidal antiinflammatory drugs (NSAIDs), 5-bromo-2-(4-fluorophenyl)-3-(4-methylsulfonylphenyl) thiophene (BFMeT), was exa
Autor:
Takemi Kinouchi, Takehito Yamamoto, Yasomi Handa, Minoru Higashimoto, Yoshinari Ohnishi, Hisao Matsumoto
Publikováno v:
Mutation Research/Genetic Toxicology. 345:155-166
The mutagenicity induced by soy sauce after reaction with 50 mM nitrite at pH 3, 37 degrees C, for 60 min in the presence of 1.25-10% ethanol was reduced in proportion to the ethanol concentration. The mutagenicity of soy sauce treated with nitrite w