Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Takeji Takamura"'
Publikováno v:
Genes and Environment, Vol 46, Iss 1, Pp 1-13 (2024)
Abstract Background An in vitro micronucleus assay is a standard genotoxicity test. Although the technique and interpretation of the results are simple, manual counting of the total and micronucleus-containing cells in a microscopic field is tedious.
Externí odkaz:
https://doaj.org/article/23e86f25788044859da58719d1203b97
Autor:
Akira Sassa, Takayuki Fukuda, Akiko Ukai, Maki Nakamura, Michihito Takabe, Takeji Takamura-Enya, Masamitsu Honma, Manabu Yasui
Publikováno v:
Genes and Environment, Vol 41, Iss 1, Pp 1-8 (2019)
Abstract Background The human genome is constantly exposed to numerous environmental genotoxicants. To prevent the detrimental consequences induced by the expansion of damaged cells, cellular protective systems such as nucleotide excision repair (NER
Externí odkaz:
https://doaj.org/article/8fb7428c7d7241948edf555c8675a1da
Autor:
Kentaro Misaki, Nguyen Minh Tue, Takeji Takamura-Enya, Hidetaka Takigami, Go Suzuki, Le Huu Tuyen, Shin Takahashi, Shinsuke Tanabe
Publikováno v:
International Journal of Environmental Research and Public Health; Volume 20; Issue 1; Pages: 80
To establish the risk of the endocrine disrupting activity of polycyclic aromatic compounds, especially oxygenated and nitrated polycyclic aromatic hydrocarbons (oxy-PAHs and nitro-PAHs, respectively), antiandrogenic and estrogenic activities were de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87fe6e943030a1b98ee57b71c1ad10b7
https://pubmed.ncbi.nlm.nih.gov/36612408
https://pubmed.ncbi.nlm.nih.gov/36612408
Publikováno v:
Entomological Research. 51:238-250
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8da527d4ee268a73f4d01905aac2608c
https://doi.org/10.1111/1748-5967.12498
https://doi.org/10.1111/1748-5967.12498
Autor:
Shuichi Masuda, Masako Ochiai, Kumiko Ogawa, Michio Sato, Yuko Shimamura, Yukari Totsuka, Takuma Kobayashi, Shinji Kishimoto, Kenji Watanabe, Yuta Tsunematsu, Yuya Tajima, Noriyuki Miyoshi, Keiji Wakabayashi, Kohei Matsushita, Takeshi Toyoda, Takanori Yamada, Takeji Takamura-Enya
Publikováno v:
Chemical Research in Toxicology. 34:912-919
Monocyclic aromatic amines, o-toluidine (o-Tol) and its structural analog o-anisidine (o-Ans), are IARC Group 1 and Group 2A urinary bladder carcinogens, respectively, and are involved in metabolic activation and DNA damage. Our recent study revealed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f66e45aa97e56d9f3755e1b97d120f81
https://doi.org/10.1021/acs.chemrestox.0c00536
https://doi.org/10.1021/acs.chemrestox.0c00536
Autor:
Sohachi Nanjo, Masanobu Abe, Naoko Iida, Tohru Niwa, Mika Wakabayashi, Takeji Takamura-Enya, Toshikazu Ushijima, Young Joon Kim, Satoshi Yamashita, Hideyuki Takeshima, Toshiro Sugiyama
Publikováno v:
J Clin Invest
Chronic inflammation is deeply involved in various human disorders, such as cancer, neurodegenerative disorders, and metabolic disorders. Induction of epigenetic alterations, especially aberrant DNA methylation, is one of the major mechanisms, but ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b21825f8e68f9890a0b233db07d07b
https://doi.org/10.1172/jci124070
https://doi.org/10.1172/jci124070
Autor:
Keiji Wakabayashi, Yukari Totsuka, Yuichiro Hirayama, Kumiko Ogawa, Takeji Takamura-Enya, Takeshi Toyoda, Kohei Matsushita, Yuya Tajima, Takanori Yamada, Kenji Watanabe, Noriyuki Miyoshi
Publikováno v:
Chemical Research in Toxicology. 33:1907-1914
o-Toluidine (o-Tol), a monocyclic aromatic amine, causes bladder cancer in humans and experimental animals and is therefore classified as a Group 1 carcinogen (IARC) in which the carcinogenicity of o-Tol is involved in metabolic activation, DNA damag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c14f2c5ed33aa36dfd1f32411101331b
https://doi.org/10.1021/acs.chemrestox.0c00098
https://doi.org/10.1021/acs.chemrestox.0c00098
Publikováno v:
Journal of Asia-Pacific Entomology. 25:101996
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9a7203eee3b2b2d2fb047526bcdf1d0
https://doi.org/10.1016/j.aspen.2022.101996
https://doi.org/10.1016/j.aspen.2022.101996
Publikováno v:
Journal of Environmental Protection. 11:610-621
The genotoxic activities of effluents from drainage water treatment plants were examined by using the novel umu tester strain NM8001, which lacks MutMst genes. To enhance the sensitivity of the LacZ assay, a BugBuster mix protein extraction reagent a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fc2c80461035036c8c55348a79960e1
https://doi.org/10.4236/jep.2020.118036
https://doi.org/10.4236/jep.2020.118036
Autor:
Soichiro Yamanaka, Yohko Kitagawa, Hiroko Nakatsukasa, Jinghua Yin, Mayumi Oda, Shimon Sakaguchi, Mana Koga-Iizuka, Yu Ichi Tsukada, Akihiko Yoshimura, Qianjin Lu, Naganari Ohkura, Jun Kohyama, Minako Ito, Ikuko Koya, Takeji Takamura-Enya, Shunsuke Chikuma, Tsukasa Sanosaka, Kazue Someya
Publikováno v:
International Immunology. 31:335-347
Ten-eleven translocation (TET) proteins regulate DNA methylation and gene expression by converting 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). Although Tet2/Tet3 deficiency has been reported to lead to myeloid cell, B-cell and invariant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3871579bf43e1df526b1cc45a4c80e98
https://doi.org/10.1093/intimm/dxz008
https://doi.org/10.1093/intimm/dxz008