Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Takehisa Watanabe"'
Autor:
Naotaka Kugiyama, Shunpei Hashigo, Katsuya Nagaoka, Takehisa Watanabe, Shinya Ushijima, Yukiko Uramoto, Motohiro Yoshinari, Jun Morinaga, Ryosuke Gushima, Masakuni Tateyama, Motohiko Tanaka, Hideaki Naoe, Yasuhiko Sugawara, Taizo Hibi, Yasuhito Tanaka
Publikováno v:
DEN Open, Vol 4, Iss 1, Pp n/a-n/a (2024)
Abstract Background Endoscopic biliary stenting is a standard treatment for biliary strictures after liver transplantation. Plastic stents are often replaced before stent dysfunction to prevent the development of cholangitis and jaundice. Therefore,
Externí odkaz:
https://doaj.org/article/4c02b4924f2e4c69b15bff0e4937ef30
Publikováno v:
Clinical and Molecular Hepatology, Vol 29, Iss 4, Pp 851-868 (2023)
The current requirement for biomarkers to detect hepatitis B virus (HBV) infection is polarized. One is a fully-automated and highly sensitive measurement system; the other is a simple system for point-of-care testing (POCT) in resource-limited areas
Externí odkaz:
https://doaj.org/article/3a36fde220dd447b8885c9d466a98452
Autor:
Satoshi Narahara, Takehisa Watanabe, Katsuya Nagaoka, Nahoko Fujimoto, Yoki Furuta, Kentaro Tanaka, Takayuki Tokunaga, Takeshi Kawasaki, Yoko Yoshimaru, Hiroko Setoyama, Kentaro Oniki, Junji Saruwatari, Masakuni Tateyama, Hideaki Naoe, Motohiko Tanaka, Yasuhito Tanaka, Yutaka Sasaki
Publikováno v:
Hepatology Communications, Vol 6, Iss 5, Pp 1198-1212 (2022)
Advanced hepatocellular carcinoma (HCC) remains a highly lethal malignancy, although several systemic therapeutic options are available, including sorafenib (SFN), which has been one of the standard treatment agents for almost a decade. As early pred
Externí odkaz:
https://doaj.org/article/45aa45a8d48f45b7b7adf065cdba44de
Autor:
Sanae Hayashi, Masanori Isogawa, Keigo Kawashima, Kyoko Ito, Natthaya Chuaypen, Yuji Morine, Mitsuo Shimada, Nobuyo Higashi-Kuwata, Takehisa Watanabe, Pisit Tangkijvanich, Hiroaki Mitsuya, Yasuhito Tanaka
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The persistence of covalently closed circular DNA (cccDNA) poses a major obstacle to curing chronic hepatitis B (CHB). Here, we used droplet digital PCR (ddPCR) for cccDNA quantitation. The cccDNA-specific ddPCR showed high accuracy with the
Externí odkaz:
https://doaj.org/article/469f5c0a15814112a295c48478b14baf
Autor:
Jun Kido, Hiroshi Mitsubuchi, Takehisa Watanabe, Keishin Sugawara, Hideo Sasai, Toshiyuki Fukao, Kimitoshi Nakamura
Publikováno v:
Human Genome Variation, Vol 8, Iss 1, Pp 1-6 (2021)
Glycogen storage disease type IX (GSD IX), the most common form of GSD, is caused by a defect in phosphorylase kinase (PhK). We describe the case of a female patient with GSD IXc harboring a homozygous mutation in PHKG2 (NM_000294.3; PHKG2 (c.280_282
Externí odkaz:
https://doaj.org/article/d64176232cbc4801ae1c3344a570e6f4
Autor:
Masakuni Tateyama, Hideaki Naoe, Motohiko Tanaka, Kentaro Tanaka, Satoshi Narahara, Takayuki Tokunaga, Takeshi Kawasaki, Yoko Yoshimaru, Katsuya Nagaoka, Takehisa Watanabe, Hiroko Setoyama, Yutaka Sasaki, Yasuhito Tanaka
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Sarcopenia is a syndrome characterized by progressive and systemic decreases in skeletal muscle mass and muscle strength. The influence or prognosis of various liver diseases in this condition have been widely investigated, but li
Externí odkaz:
https://doaj.org/article/96b8a32139ea4f7fb47b104a680e4c34
Publikováno v:
Viruses, Vol 14, Iss 7, p 1393 (2022)
Hepatitis B virus (HBV) causes acute and, most importantly, chronic hepatitis B worldwide. Antiviral treatments have been developed to reduce viral loads but few patients with chronic hepatitis B (CHB) achieve a functional cure. The development of ne
Externí odkaz:
https://doaj.org/article/5e49cbcb9d7148ffab13d28bc6710b0d
Publikováno v:
Asian Journal of Atmospheric Environment, Vol 12, Iss 3, Pp 274-288 (2018)
Quantitative data of 50 non-polar organic compounds constituting PM2.5 were continuously collected and analyzed from June 2016 to October 2017 (approximately 17 months) at Ichihara, one of the largest industrial areas in Japan. Target nonpolar organi
Externí odkaz:
https://doaj.org/article/82df8d84df6d42c6bdfdfb70e6f3a26a
Publikováno v:
Microorganisms, Vol 9, Iss 10, p 2083 (2021)
The hepatitis B core-related antigen (HBcrAg) is an unprecedented novel HBV biomarker that plays an essential role in reflecting covalently closed circular DNA (cccDNA) in chronic hepatitis B (CHB) because its levels correlate with intrahepatic cccDN
Externí odkaz:
https://doaj.org/article/96134693c0da4ba9a69e4f01393e06b5
Autor:
Masafumi Nakamoto, Ko Ishihara, Takehisa Watanabe, Akiyuki Hirosue, Shinjiro Hino, Masanori Shinohara, Hideki Nakayama, Mitsuyoshi Nakao
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169225 (2017)
Glucocorticoid signaling through the glucocorticoid receptor (GR) plays essential roles in the response to stress and in energy metabolism. This hormonal action is integrated to the transcriptional control of GR-target genes in a cell type-specific a
Externí odkaz:
https://doaj.org/article/113535f6c4924d959a67ec0ebee02c4c