Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Takehiro Yamaguchi"'
Autor:
Yuriko Ozeki, Akira Yokoyama, Akihito Nishiyama, Yutaka Yoshida, Yukiko Ohara, Tsukasa Mashima, Chikako Tomiyama, Amina K. Shaban, Atsuki Takeishi, Mayuko Osada-Oka, Takehiro Yamaguchi, Yoshitaka Tateishi, Jun-ichi Maeyama, Mariko Hakamata, Hiroshi Moro, Toshiaki Kikuchi, Daisuke Hayashi, Fumiko Suzuki, Toshiko Yamamoto, Sumiko Iho, Masato Katahira, Saburo Yamamoto, Sohkichi Matsumoto
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Tuberculosis remains a large health threat, despite the availability of the tuberculosis vaccine, BCG. As BCG efficacy gradually decreases from adolescence, BCG-Prime and antigen-booster may be an efficient strategy to confer vaccine efficac
Externí odkaz:
https://doaj.org/article/a10feaf842bd44689e7b9167914db0a3
Autor:
Hiroki Uchiyama, Toshifumi Kudo, Takehiro Yamaguchi, Nozomu Obana, Kenji Watanabe, Kimihiro Abe, Hidetaka Miyazaki, Masanori Toyofuku, Nobuhiko Nomura, Yukihiro Akeda, Ryoma Nakao
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTThere is a growing interest in development of novel vaccines against respiratory tract infections, due to COVID-19 pandemic. Here, we examined mucosal adjuvanticity and the mucosal booster effect of membrane vesicles (MVs) of a novel probioti
Externí odkaz:
https://doaj.org/article/f9ac0a5cea9a47029ede47ea185d23ea
Autor:
Amina K. Shaban, Gebremichal Gebretsadik, Mariko Hakamata, Hayato Takihara, Erina Inouchi, Akihito Nishiyama, Yuriko Ozeki, Yoshitaka Tateishi, Yukiko Nishiuchi, Takehiro Yamaguchi, Naoya Ohara, Shujiro Okuda, Sohkichi Matsumoto
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Survival of the live attenuated Bacillus Calmette-Guérin (BCG) vaccine amidst harsh host environments is key for BCG effectiveness as it allows continuous immune response induction and protection against tuberculosis. Mycobacterial DNA bind
Externí odkaz:
https://doaj.org/article/61dd04c5205849a3bb027beab3339312
Autor:
Risa Imamiya, Akari Shinohara, Daisuke Yakura, Takehiro Yamaguchi, Koji Ueda, Ami Oguro, Yukiko Minamiyama, Hiroshi Ichikawa, Yasuhiko Horiguchi, Mayuko Osada-Oka
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Extracellular vesicles are considered to be an inflammatory factor in several acute and chronic inflammatory diseases. The present study shows that exosomes from macrophages (Mφ) infected with live Escherichia coli induced secretion of proi
Externí odkaz:
https://doaj.org/article/042618eeaf5546eea14393108ff87fa2
Autor:
Yukiko Nishiuchi, Yoshitaka Tateishi, Hiroshi Hirano, Yuriko Ozeki, Takehiro Yamaguchi, Mari Miki, Seigo Kitada, Fumito Maruyama, Sohkichi Matsumoto
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Pathogenic intracellular mycobacteria, such as Mycobacterium tuberculosis and Mycobacterium avium, which cause lung diseases, can grow in macrophages. Extracellular mycobacteria have been reported in the lungs, blood, and sputum of patients,
Externí odkaz:
https://doaj.org/article/2836573465234ae789ba940bf79b33e4
Autor:
Shunji Nishide, Junji Uchida, Shinji Matsunaga, Kentaro Tokudome, Takehiro Yamaguchi, Kazuya Kabei, Taiki Moriya, Katsuyuki Miura, Tatsuya Nakatani, Shuhei Tomita
Publikováno v:
Journal of Pharmacological Sciences, Vol 143, Iss 2, Pp 122-126 (2020)
Tumor blood vessels have leaky and low blood flow properties, which lead to hypoxia and low nutrient levels in the tumor tissue area known as the tumor microenvironment (TME). We reported that the prolyl-hydroxylase (PHD) inhibitor Roxadustat normali
Externí odkaz:
https://doaj.org/article/710a0948a85942fbbe28c400d0dc2919
Autor:
Kazuya Kabei, Yu Tateishi, Masayuki Shiota, Mayuko Osada-Oka, Shunji Nishide, Junji Uchida, Tatsuya Nakatani, Shinji Matsunaga, Takehiro Yamaguchi, Shuhei Tomita, Katsuyuki Miura
Publikováno v:
Journal of Pharmacological Sciences, Vol 142, Iss 3, Pp 93-100 (2020)
Orally active hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitors that stabilize HIF protein and stimulate the production of erythropoietin have been approved to treat renal anemia. Our previous report suggested that HIF-1α dependent fibrog
Externí odkaz:
https://doaj.org/article/17c0ded9287f4256853a60340d7e9d8f
Autor:
Shunji Nishide, Shinji Matsunaga, Masayuki Shiota, Takehiro Yamaguchi, Shojiro Kitajima, Yoichi Maekawa, Norihiko Takeda, Michio Tomura, Junji Uchida, Katsuyuki Miura, Tatsuya Nakatani, Shuhei Tomita
Publikováno v:
iScience, Vol 19, Iss , Pp 940-954 (2019)
Summary: The tumor microenvironment (TME) polarizes tumor-infiltrating macrophages toward tumor support. Macrophage-abundant tumors are highly malignant and are the cause of poor prognosis and therapeutic resistance. In this study, we show that the p
Externí odkaz:
https://doaj.org/article/aed9b1b9ca424045a5ae836419c33aa8
Autor:
Takehiro Yamaguchi, Ayano Watanabe, Masako Tanaka, Masayuki Shiota, Mayuko Osada-Oka, Soichi Sano, Minoru Yoshiyama, Katsuyuki Miura, Shojiro Kitajima, Shinji Matsunaga, Shuhei Tomita, Hiroshi Iwao, Yasukatsu Izumi
Publikováno v:
Journal of Pharmacological Sciences, Vol 139, Iss 2, Pp 112-119 (2019)
Dipeptidyl peptidase-4 (DPP-4) inhibitors not only improve impaired glucose tolerance in diabetes, but also have pleiotropic extra-pancreatic effects such as preconditioning effect for myocardial ischemia-reperfusion injury. Here, we investigated the
Externí odkaz:
https://doaj.org/article/aedde71edce74b8aab104d5a56d50bef
Autor:
Manabu Inoue, Mamiko Niki, Yuriko Ozeki, Sachiyo Nagi, Evans Asena Chadeka, Takehiro Yamaguchi, Mayuko Osada-Oka, Kenji Ono, Tetsuya Oda, Faith Mwende, Yukihiro Kaneko, Makoto Matsumoto, Satoshi Kaneko, Yoshio Ichinose, Sammy M. Njenga, Shinjiro Hamano, Sohkichi Matsumoto
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Immune responses to parasitic pathogens are affected by the host physiological condition. High-density lipoprotein (HDL) and low-density lipoprotein (LDL) are transporters of lipids between the liver and peripheral tissues, and modulate pro-
Externí odkaz:
https://doaj.org/article/24ac1e4da1684968ba9bb16119a34aa4