Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Takehiro Uchibori"'
Autor:
Takashi Konno, Akira Murakami, Takehiro Uchibori, Akihiko Nagai, Kentaro Kogi, Norimichi Nakahata
Publikováno v:
Journal of Pharmacological Sciences, Vol 97, Iss 4, Pp 501-509 (2005)
The aim of the present study is to clarify the mechanism for the decrease in intraocular pressure by 2-alkynyladenosine derivatives in rabbits. The receptor binding analysis revealed that 2-(1-octyn-1-yl)adenosine (2-O-Ado) and 2-(6-cyano-1-hexyn-1-y
Externí odkaz:
https://doaj.org/article/14fbc00fb5114c08b9413ee949a43791
Autor:
Yoichi Manome, Yohei Abe, Kouichi Tanonaka, Tetsuro Marunouchi, Takehiro Uchibori, Jun Sasamori
Publikováno v:
Biologicalpharmaceutical bulletin. 38(12)
This study investigated the effects of an adenosine receptor agonist, 2-octynyladenosine (YT-146), on mitochondrial function in ischemic and ischemic/reperfused hearts. Isolated rat hearts were perfused in the Langendorff manner with a constant flow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb965c6f34ac261b4ad4944ee30a1d4
https://pubmed.ncbi.nlm.nih.gov/26632185
https://pubmed.ncbi.nlm.nih.gov/26632185
Autor:
Takehiro Uchibori, Kentaro Kogi, Mizuo Miyazaki, Tsunehiko Ikeda, Tetsuya Sugiyama, Midori Maruichi, Hidehiro Oku, Shinji Takai, Akihiko Nagai, Takashi Konno
Publikováno v:
European Journal of Pharmacology. 524:132-137
Chymase is a chymotrypsin-like serine protease that is stored exclusively in the secretory granules of mast cells and converts big endothelins to endothelin-1 (1-31). The aim of this study was to evaluate the effect of chymase on intraocular pressure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181df8a9a7ab6509520bd9ae29cf5942
https://doi.org/10.1016/j.ejphar.2005.09.048
https://doi.org/10.1016/j.ejphar.2005.09.048
Autor:
Satoshi Takeo, Takehiro Uchibori, Atsuo Takahashi, Jun Sasamori, Kazuyuki Aihara, Kouichi Tanonaka
Publikováno v:
Journal of cardiovascular pharmacology. 57(2)
The present study was aimed at investigating the cardiac receptor subtypes involved in the cardioprotective effects of 2-octynyladenosine (YT-146), a novel adenosine receptor (AR) agonist. Isolated rat hearts were perfused in the Langendorff manner,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d37d3d75ab98a3ebbe95d817807eeb
https://pubmed.ncbi.nlm.nih.gov/21052018
https://pubmed.ncbi.nlm.nih.gov/21052018
Publikováno v:
Japanese Journal of Pharmacology. 57:153-165
We investigated the cardiovascular effects of 2-octynyladenosine (YT-146), an adenosine A2 agonist, in various mammalian preparations in comparison with adenosine and 2-chloroadenosine. YT-146, when intravenously administered, caused a dose-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72184c3dec1e4bb421bcf88eea8aff4b
https://doi.org/10.1254/jjp.57.153
https://doi.org/10.1254/jjp.57.153
Autor:
Kentaro Kogi, Akira Murakami, Takehiro Uchibori, Takashi Konno, Norimichi Nakahata, Akihiko Nagai
Publikováno v:
Journal of Pharmacological Sciences, Vol 97, Iss 4, Pp 501-509 (2005)
The aim of the present study is to clarify the mechanism for the decrease in intraocular pressure by 2-alkynyladenosine derivatives in rabbits. The receptor binding analysis revealed that 2-(1-octyn-1-yl)adenosine (2-O-Ado) and 2-(6-cyano-1-hexyn-1-y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eadbf7fd0a2231f04b2ae64b47dfd2b4
https://pubmed.ncbi.nlm.nih.gov/15821340
https://pubmed.ncbi.nlm.nih.gov/15821340
Publikováno v:
European journal of pharmacology. 518(2-3)
The present study was performed to clarify the mechanism of change in intraocular pressure by 2-(1-hexyn-1-yl)adenosine (2-H-Ado), a selective adenosine A2 receptor agonist, in rabbits. 2-H-Ado (0.1%, 50 microl)-induced ocular hypertension (E(max): 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df475cb87de26c08ab2181198d29df02
https://pubmed.ncbi.nlm.nih.gov/16023100
https://pubmed.ncbi.nlm.nih.gov/16023100
Autor:
Takehiro Uchibori, Kazuki Endo, Kentaro Kogi, Takashi Konno, Norimichi Nakahata, Akihiko Nagai, Kazuhiro Uemoto, Tomokazu Hosokawa, Shinya Ohnuma
Publikováno v:
European journal of pharmacology. 486(3)
We evaluated the activities of 2-alkynyladenosine derivatives, relatively selective adenosine A2 receptor agonists, in the intraocular pressure regulation in rabbits. An adenosine A2 receptor agonist 2-[p-(2-carboxyethyl)phenylethylamino]-5′-N-ethy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640e10d6ad9759638117d529fec029a3
https://pubmed.ncbi.nlm.nih.gov/14985053
https://pubmed.ncbi.nlm.nih.gov/14985053
Publikováno v:
Japanese Journal of Pharmacology. 36:177
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14180e5f6d9409c83d508ffa8a702017
https://doi.org/10.1016/s0021-5198(19)62561-8
https://doi.org/10.1016/s0021-5198(19)62561-8